- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Liver physiology and pathology
- Pediatric Hepatobiliary Diseases and Treatments
- Cardiac Ischemia and Reperfusion
- Mitochondrial Function and Pathology
- Metabolism and Genetic Disorders
- Organ Donation and Transplantation
- Photodynamic Therapy Research Studies
- Clinical Nutrition and Gastroenterology
- Palliative and Oncologic Care
- Congenital Anomalies and Fetal Surgery
- Spectroscopy Techniques in Biomedical and Chemical Research
- Nanoplatforms for cancer theranostics
- Gallbladder and Bile Duct Disorders
- Hepatocellular Carcinoma Treatment and Prognosis
- Drug-Induced Hepatotoxicity and Protection
- Health, Nursing, Elderly Care
- Laser Applications in Dentistry and Medicine
- Pancreatic function and diabetes
- Diet and metabolism studies
- Bariatric Surgery and Outcomes
- Renal Transplantation Outcomes and Treatments
- Eosinophilic Esophagitis
University of Colombo
2024
Universidade de São Paulo
2013-2023
Universidade de Ribeirão Preto
2011-2022
Fundação Hospitalar do Estado de Minas Gerais
2019
Directorate-General for Interpretation
2018
Clinics Hospital of Ribeirão Preto
2009-2018
Universidade Brasil
2007-2018
Hospitais da Universidade de Coimbra
2018
Cincinnati Children's Hospital Medical Center
2016
Respons
2014
A isquemia tem papel fundamental em muitas situações clínicas perioperatórias . Apesar da revascularização sanguínea a um órgão isquêmico seja essencial para prevenir irreversibilidade lesão celular, reperfusão pode agravar as lesões produzidas na fase isquêmica isolada. Assim, o dano celular induzido após de é denominado isquemia-reperfusão (I/R). Aspectos básicos I/R, são revisados neste artigo.
The efficacy of photodynamic therapy (PDT) depends on a variety parameters: concentration the photosensitizer at time treatment, light wavelength, fluence, fluence rate, availability oxygen within illuminated volume, and distribution in tissue. Dosimetry PDT requires congregation adequate amounts light, drug, tissue oxygen. dosimetry should be able to predict extension damage. Photosensitizer photobleaching rate molecular Based photosensitizers models, high has associated with production...
Abstract Human leukocyte antigen‐G ( HLA ‐G) is a nonclassical class I molecule involved in tumor escape mechanisms. Considering that the ‐G 14bp insertion/deletion polymorphism located at 3′ untranslated region (3′ UTR ) exon 8, and since it has been associated with magnitude of production, we studied association risk developing hepatocellular carcinoma HCC ). A total 109 patients followed University Hospital, Faculty Medicine Ribeirão Preto, São Paulo, Brazil, 202 healthy controls from...
Objective: The goal of this study is to determine the optical properties different rat tissues with respect spatial intensity variation and light distribution. We are interested mainly in wavelength 630 nm. Nevertheless, for liver tissue we have used 514 nm 670 as well. Background Data: In past, many articles been written about interaction lasers tissues. However, technique imaging distribution allows us obtain scattering well an effective attenuation coefficient intensity. Methods: Slices...
The use of medicinal plants for the treatment human diseases has increased worldwide. Many them are used by oral administration and, after absorption, may affect many organs. Therefore, this study aimed at assessing effects aqueous extract Sida cordifolia leaves, popularly known in Brazil as "malva-branca", on liver regeneration.Twenty rats were divided into four groups: control, Sida100, Sida200 and Sida400 groups. All animals submitted to distilled water, 100, 200 400 mg/kg cordifolia,...
Liver transplantation represents the most effective therapy for patients suffering from chronic end-stage liver disease. Until very recently, in Brazil, allocation was based on Child-Turcotte-Pugh score and waiting list followed a chronological criterion. In February 2002 Model End-stage Disease (MELD) adopted of donor livers US. After that change, an increased number with more severe disease observed, although there no difference 1-year patient graft survival. A reduction waiting-list...
We have investigated a possible correlation between the photostability and photodynamic efficacy for different photosensitizers; hematoporphyrin derivatives chlorines. To perform such analysis, we combined depth of necrosis (d nec) measurement, expressed by light threshold dose photodegradation parameter, measured from investigation photosensitizer degradation in solution. The d nec analysis allows us to determine compare its value with existent results literature. use simple models...
Background Data: Photodynamic therapy (PDT) involves the photoinduction of cytotoxicity using a photosensitizer agent, light source proper wavelength, and presence molecular oxygen. A model for tissue response to PDT based on photodynamic threshold dose (Dth) has been widely used. In this cells exposed doses below Dth survive while at above necrosis takes place. Objective: This study evaluated values by two different methods determination. One concerns depth other width superficial necrosis....
Abstract Background and Objectives The low intensity laser therapy (LILT) has been widely used in all medical fields due to its therapeutic effects reparative process, pain relief, biostimulation. Even though there is a window of wavelengths for clinical application, little done concerning the frequency spectrum response biological effects. In this work, we investigate dependence different irradiation enhancement tissue regeneration after partial hepatectomy Wistar rats. Study...
To evaluate the accuracy of different parameters in predicting early (one-month) mortality patients submitted to orthotopic liver transplantation (OLT).This is a retrospective study forty-four (38 males and 10 females, mean age 52.2 ± 8.9 years) admitted Intensive Care Unit tertiary hospital. Serial lactate blood levels, APACHE II, MELD post-OLT, creatinine, bilirubin INR were analyzed by receiver-operator characteristic (ROC) curves as evidenced area under curve (AUC). The level...