A5079111898- Commutative Algebra and Its Applications
- Diabetes Management and Research
- RNA modifications and cancer
- Hormonal Regulation and Hypertension
- Liver Disease Diagnosis and Treatment
- Lipid metabolism and disorders
- Cancer-related molecular mechanisms research
- Effects and risks of endocrine disrupting chemicals
- Diabetes Treatment and Management
- Animal testing and alternatives
- Advanced Mathematical Identities
- Nutrition, Genetics, and Disease
- Polynomial and algebraic computation
- RNA Research and Splicing
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2023
Beijing Hospital
2022
Glucocorticoids are essential participants in the regulation of lipid metabolism.On a tissue-specific level, glucocorticoid signal is controlled by 11β-Hydroxysteroid dehydrogenase 1 (11β-HSD1).Up-regulation 11β-HSD1 expression during non-alcoholic fatty liver disease (NAFLD) has been previously shown, while inhibition shown to reduce hepatic lipids NAFLD, but underlying mechanisms remain unclear.Here, this study, we created vitro cell culture and vivo transgenic hepatocyte-specific mouse...
In 2008, Chebikin considered the $cd$-index of $\mathfrak{S}_n$ with respect to alternating descent statistic and asked for a combinatorial interpretation its coefficients. this paper, we provide an answer Chebikin's open problem in terms permutations without double descents ending ascent, new defined on these permutations. Additionally, demonstrate approach proving gamma-expansions Eulerian polynomials. Furthermore, offer direct their gamma-coefficients.
Background Infertility is recognized as a common and worrisome problem of human reproduction worldwide. Based on previous studies, male factors account for about half all infertility cases. Exposure to environmental toxicants an important contributor infertility. Bisphenol A (BPA) the most prominent toxic contaminant worldwide affecting reproductive system. BPA can impair function Golgi apparatus which in spermatogenesis. GGA1 known Golgi-localized, gamma adaptin ear-containing, ARF-binding...