A5022597358- Plant Molecular Biology Research
- Plant tissue culture and regeneration
- CRISPR and Genetic Engineering
- Chromosomal and Genetic Variations
- Plant Reproductive Biology
- Microplastics and Plastic Pollution
- Plant Parasitism and Resistance
- Plant nutrient uptake and metabolism
- Plant Virus Research Studies
- Legume Nitrogen Fixing Symbiosis
- Food and Agricultural Sciences
- Plant Stress Responses and Tolerance
- Plant and fungal interactions
- Coconut Research and Applications
- Light effects on plants
- Microbial Community Ecology and Physiology
- Plant Diversity and Evolution
- Heavy Metal Exposure and Toxicity
- Probiotics and Fermented Foods
- Medicinal Plant Research
- Phytochemicals and Antioxidant Activities
- Heavy metals in environment
- Recycling and Waste Management Techniques
- Plant Genetic and Mutation Studies
- Plant and Fungal Species Descriptions
Airlangga University
2019-2024
University of Warwick
2012-2022
Max Planck Institute for Developmental Biology
2018-2022
Universitas 17 Agustus 1945 Surabaya
2018
Universitas Gadjah Mada
2016
King Abdullah University of Science and Technology
2011-2012
University of Oxford
2012
Site-specific and rare cutting nucleases are valuable tools for genome engineering. The generation of double-strand DNA breaks (DSBs) promotes homologous recombination in eukaryotes can facilitate gene targeting, additions, deletions, inactivation. Zinc finger have been used to generate DSBs subsequently, editing but with low efficiency reproducibility. transcription activator-like family type III effectors (TALEs) contains a central domain tandem repeats that could be engineered bind...
Inducible epigenetic changes in eukaryotes are believed to enable rapid adaptation environmental fluctuations. We have found distinct regions of the Arabidopsis genome that susceptible DNA (de)methylation response hyperosmotic stress. The stress-induced associated with conditionally heritable adaptive phenotypic stress responses. However, these responses primarily transmitted next generation through female lineage due widespread glycosylase activity male germline, and extensively reset...
Approximately 381 million tons of plastic are produced globally every year, and the majority it ends up as pollutants. In environment, waste is fragmented into microplastic particles less than 5 mm in size; owing to their small size, durability, abundance, they can easily be dispersed, incorporated food chains, enter human body. The extent exposure body has become a major concern many countries, including Indonesia, second largest contributor world. Here, we report detection microplastics...
Ionizing radiation has long been known to induce heritable mutagenic change in DNA sequence. However, the genome-wide effect of is not well understood. Here we report molecular properties and frequency mutations phenotypically selected mutant lines isolated following exposure genetic model flowering plant Arabidopsis thaliana fast neutrons (FNs). Previous studies suggested that FNs predominantly deletions longer than a kilobase A. . found higher single base substitution deletion mutations....
Plants differ from animals in their capability to easily regenerate fertile adult individuals terminally differentiated cells. This unique developmental plasticity is commonly observed nature, where many species can reproduce asexually through the ectopic initiation of organogenic or embryogenic programs. While organ-specific epigenetic marks are not passed on during sexual reproduction, fate asexual reproduction and implications for clonal progeny remain unclear. Here we report that...
Plastic is one of the most abundant pollutants in environment. As a result natural physical processes, large plastic waste degraded into microsized particles (<5 mm) called microplastics. Because their size, abundance, and durability, microplastics are widely distributed environment, contaminating food water intended for human consumption. The extent microplastic contamination body still unclear because there few studies concerning specimens and, studies, data were collected from city...
Histone modifications deposited by the Polycomb repressive complex 2 (PRC2) play a critical role in control of growth, development, and adaptation to environmental fluctuations most multicellular eukaryotes. The catalytic activity PRC2 is counteracted Jumonji-type (JMJ) histone demethylases, which shapes genomic distribution H3K27me3. Here, we show that two JMJ demethylases Arabidopsis , EARLY FLOWERING 6 (ELF6) RELATIVE OF (REF6), distinct roles H3K27me3 H3K27me1 homeostasis. We failure...
Microplastics are major pollutants in the environment, and it is currently established that microplastics have already entered human food chains been incorporated into body through ingestion inhalation. Several works animal models reported adverse effect of microplastic exposure on biological systems; however, contamination health still far from understood. In previous work, we digestive tract Indonesian coastal highland population. Using same stool samples, extended our work by...
Jamaican cherry (Muntinga calabura Linn.) is tropical tree that known to produce edible fruit with high nutritional and antioxidant properties. However, its use as functional food still limited. Previous studies suggest fermentation probiotic bacteria could enhance the properties of non-dairy products, such juices. In this study, we analyze metabolite composition activity juice following Lactobacillus plantarum FNCC 0027 in various substrate compositions. The profile after was analyzed using...
Antibiotic resistance is a global public health concern that has been exacerbated by the overuse and misuse of antibiotics, leading to emergence resistant bacteria. The gut microbiota, often influenced antibiotic usage, plays crucial role in overall health. Therefore, this study aimed investigate prevalence genes microbiota Indonesian coastal highland populations, as well identify vancomycin-resistant bacteria their genes.
The environmental microbiome plays an important role in various ecosystems around the world, influencing nutrient cycling, disease dynamics and ecosystem stability. This bibliometric analysis provides a comprehensive overview of current state future directions research from global perspective 2009–2024. Through systematic examination Scopus publications, 2154 documents were found. results show significant increase number publications since 2017 peak 2024. most cited document was "The hidden...
Soil salinity and mineral deficiency are major problems in agriculture. Many studies have reported that plant-associated microbiota, particularly rhizosphere root play a crucial role tolerance against deficiency. Nevertheless, there still many unknown parts of plant-microbe interaction, especially regarding their halophyte adaptation to coastal ecosystems. Here, we report the bacterial community associated with roots sand dune halophytes Spinifex littoreus Calotropis gigantea, soil...
This study aimed to determine the prevalence of multidrug-resistant (MDR) bacterial isolates in urinary tract infections (UTI) patients Indonesia, where access appropriate antibiotic treatment may be limited. A cross-sectional was conducted from January 2020 December 2022, with 308 UTIs cultured and tested for antimicrobial susceptibility. The most identified isolate Escherichia coli (39.6 %), followed by Klebsiella pneumoniae (11.6 %) Staphylococcus spp. (11.03 %). overall MDR 35 %, highest...
Abstract Background Cymbopogon is a member of the family Poaceae and has been explored for its phytochemicals bioactivities. Although antimicrobial activities spp . extracts have extensively studied, comprehensive analyses are required to identify promising compounds treatment resistance. Therefore, this study investigated antioxidant properties spp. ethanolic in every single organ. Methods Ethanolic were obtained from three Indonesian commercial species , namely citratus (L.) Rendle nardus...
Clonal propagation is frequently used in commercial plant breeding and biotechnology programs because it minimizes genetic variation, yet not uncommon to observe clonal plants with stable phenotypic changes, a phenomenon known as somaclonal variation. Several studies have linked epigenetic modifications induced during regeneration this newly acquired However, the factors that determine extent of variation molecular changes underpinning process remain poorly understood. To address gap our...
Exposure to cadmium (Cd) could increase of reactive oxygen species (ROS) and changes in expression antioxidant genes. Gynura procumbens is a medicinal plant that rich phenolic flavonoid compounds. The aimed study evaluate the hepatoprotective effect G. adventitious root (GAR) extract against Cd toxicity, especially rate hepatic Twenty-five male mice were treated as follows: P1 (control), P2 (Cd100mg/L), P3 (GAR100mg/L + Cd100mg/L), P4 (GAR200mg/L P5 (GAR300mg/L Cd100mg/L). samples (blood...
Abstract Despite being valuable for producing a natural sweetener Curculin, Curculigo latifolia has low growth and difficult to domestificate. So, solve this problem, propagation on in vitro culture will be an alternative method propagated spesies under different cytokinins light condition. Cytokinins major role organogenesis, gene expression of many species. Thus, study, we aimed improve the condition curculin by combining addition exposure. Four weeks seedlings were sub-cultured into...
Abstract Background: Lead exposure is a growing concern in recent public health because lead acts as an oxidant, causing oxidative stress. In this context, the administration of exogenous antioxidants imperative. Our preliminary study revealed that Gynura procumbens leaf and root contain phenolics flavonoids. The current aims to determine potency G. adventitious (ARGp) preventing stress caused by potential anti-cancer agent. Methods: ARGp was induced from explant, propagated inside...
Abstract. Geraldi A, Clement C, Pertiwi MD, Lestari Y, Parinnata DH, Arsad RN, Sadikin RA, Luqman Santoso H, Kristanti AN, Manuhara YSW, Wibowo AT. 2024. Isolation and characterization of plant growth-promoting bacteria from medicinal plants Java cardamom (Amomum compactum) bitter ginger (Zingiber zerumbet). Biodiversitas 25: 2556-2564. zerumbet) are valuable native to Indonesia with significant economic pharmacological importance. While their properties have been extensively studied, little...
Common carp (Cyprinus carpio Linnaeus 1758) is grouped into Family Cyprinidae and Order Cypriniformes. One of Indonesian common which commonly domesticated in Indonesia to fulfil consumer needs animal protein “Majalaya”. Even though the “Majalaya” extensively meet market demands, any comprehensive study on fish chromosomes has not been investigated. Chromosome quite important related breeding program including certification process. The objective this was karyotype collected from UKBAT...