A5049820421- Medical Imaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Adipose Tissue and Metabolism
- Thyroid Cancer Diagnosis and Treatment
- Cardiac Imaging and Diagnostics
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Diet and metabolism studies
- Neuroendocrine Tumor Research Advances
- Radiomics and Machine Learning in Medical Imaging
- Adipokines, Inflammation, and Metabolic Diseases
- Infectious Diseases and Tuberculosis
- Radiopharmaceutical Chemistry and Applications
- Thyroid and Parathyroid Surgery
- Cancer Immunotherapy and Biomarkers
- Prostate Cancer Treatment and Research
- Exercise and Physiological Responses
- Musculoskeletal synovial abnormalities and treatments
- Dementia and Cognitive Impairment Research
- Head and Neck Anomalies
- Urologic and reproductive health conditions
- Sarcoidosis and Beryllium Toxicity Research
- Cardiovascular Function and Risk Factors
- Orthopedic Infections and Treatments
- Prostate Cancer Diagnosis and Treatment
- Hematological disorders and diagnostics
The Alfred Hospital
2012-2025
Monash University
2012-2025
Alfred Health
2013-2025
Peter MacCallum Cancer Centre
2018
Baker Heart and Diabetes Institute
2013
Austin Health
2007
Austin Hospital
2006
The University of Melbourne
2006
Amyloid-β (Aβ) imaging with <i>N</i>-methyl-<sup>11</sup>C-2-(4′-methylamino-phenyl)-6-hydroxy-benzothiazole (<sup>11</sup>C-6-OH-BTA-1; also known as <sup>11</sup>C-PIB) shows a robust increase in cortical binding Alzheimer9s disease (AD). The aim of this study was to explore the clinical potential Aβ for diagnosis AD by comparison accuracy visual reading <sup>11</sup>C-PIB images quantitative analysis and <sup>18</sup>F-FDG. <b>Methods:</b> Fifteen patients (age, 71.1 ± 11.3 y [mean SD];...
Objective To compare the accuracy of 68 gallium prostate‐specific membrane antigen positron emission tomography/computed tomography ( Ga‐PSMA PET/CT) with multiparametric MRI (mpMRI) in detecting and localising primary prostate cancer when compared radical prostatectomy (RP) specimen pathology. Patients methods Retrospective review men who underwent PET/CT mpMRI for before RP across four centres between 2015 2018. undergoing imaging recurrent disease or non‐surgical treatment were excluded....
To evaluate the effects of long-acting somatostatin analogue (SSA) therapy on 68Ga-DOTA-octreotate (GaTate) uptake at physiological and metastatic sites in neuroendocrine tumour (NET) patients.Twenty-one patients who underwent GaTate PET/CT before after commencement SSA were reviewed. Maximum standardized values (SUVmax) measured normal organs. Changes 49 lesions 12 with stable disease also compared. Serum chromogranin-A (CgA) levels available for correlation between scans 17/21...
18 F-FDG PET/CT scanning is routinely performed to stage and evaluate the treatment response in many malignancies. Immunotherapy a rapidly growing option for cancers, both clinicians imaging specialists need be familiar with characteristics unique patients on this type of treatment. In particular, immune-related adverse events (irAEs) can detected early accurate identification critical reduce related morbidity incorrect interpretation malignant disease status. This pictorial essay reviews...
A 42-year-old woman presented with a rapidly enlarging right-sided thyroid mass and underwent hemithyroidectomy. Riedel's thyroiditis was only diagnosed upon surgical decompression of the right carotid artery 2 years later. She became more symptomatic as progressed, mediastinal fibrosclerosis developed over next 12 months. Oral prednisolone failed to improve her condition, she commenced on tamoxifen. Despite initial improvement, symptoms recurred later, mainly arising from compression...
Abstract There have been several case reports of COVID-19 “BNT162b2” (Pfizer-BioNTech) and “mRNA-1273” (Moderna) vaccination associated small medium vessel vasculitis described in the literature however none had 18 F-FDG Positron Emission Tomography scans (PET/CT) performed for diagnosis. We report a 57-year-old Caucasian male patient from Australia where PET/CT scanning facilitated early detection medium-vessel following Moderna (mRNA-1273) vaccination. The diagnosis would otherwise...
Abstract Objectives To evaluate the relationship between total lesion PSMA (PSMA TL ), serum PSA, histopathological findings and biochemical recurrence (BCR) in patients with localised prostate cancer (PCa). Patients methods This retrospective study assessed men undergoing 68 Ga‐PSMA‐11 PET/CT for newly diagnosed or treatment‐naïve PCa to gland. Volumes of interest were manually mapped derive SUV max , mean PSMA‐avid tumour volume . was defined as product primary Spearman correlation tests...
Background: Accurate pre-operative clinical staging is vital for guiding treatment decisions in resectable non-small cell lung cancer (NSCLC). Discrepancies between and pathological stages raise concerns about appropriateness. Objective: The objective of the study to determine accuracy stage (cTN) with post-operative (pTN), examine factors predictive inaccurate explore impacts on survival. Patient Methods: This retrospective cohort Melbourne, Australia, analyzed I-IIIA NSCLC patients...
To evaluate the incidence and clinical implications of a positive whole-body I-131 scan but negative stimulated serum Tg/TgAb level following an ablative or diagnostic dose in patients with well-differentiated thyroid cancer whether there is difference if prepared hormone withdrawal compared rhTSH stimulation.I-131 findings, levels, TNM stage method tissue stimulation 193 consecutive (138F, 55M) undergoing postoperative therapy 121 (94F, 27M) surveillance scans were retrospectively reviewed....
Aim To evaluate clinical response rates, duration of and complication rates yttrium radiosynovectomy (RSV) in an era improved disease modifying antirheumatic drugs (DMARDS) increased access to replacement therapy for clotting factor deficiencies introduced the mid 2000s. Methods A retrospective review 167 consecutive joints treated with RSV between 2000 2010 was conducted. Clinical (119 patients: 45 female,74 male, mean age 52 years) rheumatoid, psoriatic, hemophilic, large joint...
To evaluate the relationships between thyroid remnant (131)I uptake, radiation thyroiditis and ablation success rate lower (1110 MBq) higher (3700 initial ablative dose for post-surgical therapy differentiated cancer.Patients having administration of 1110 MBq (68 patients) or 3700 (115 were retrospectively reviewed. Thyroid uptake on a 48 h post-administration scan was correlated with neck symptoms experienced. Patients classified as insignificant, mild severe based symptoms. Absent bed...
The aims of this study were (i) to assess and validate the incremental information positron emission tomography/computed tomography (PET/CT) over conventional staging investigations (CSI) (ii) management impact PET/CT in patients with known or suspected pancreatic cancer.Between October 2007 September 2008, 22 scans performed using a dedicated scanner 21 cancer. Follow up was used reconcile discordance between CSI. pre-PET/CT plan and/or intent prospectively recorded all scans. post-PET/CT...
Metastatic malignancy to the thyroid gland is generally uncommon due an unfavourable local micro-environment which impairs ability of metastatic cells settle and thrive. Metastases have however been reported occur occasionally particularly if there has disruption normal tissue architecture. We report a patient with history surgically resected rectal adenocarcinoma who presents rising serum CEA level 18F-FDG PET scan positive nodule was subsequently confirmed at surgery be focus within...
Abstract Introduction The aim of this study is to compare the results positron emission tomography ( PET )/ CT with bremsstrahlung imaging following Y ‐90 radiation synovectomy. Methods All patients referred our institution for synovectomy between J uly 2011 and F ebruary 2012 underwent both / planar (± single photon computed SPECT ) or at 4 24 h administration silicate colloid. image acquisition was performed 15 20 min. In who , side‐by‐side comparison quality/resolution scored using a...
The occurrence of granulomatous disease in the setting Hodgkin's is rare; however, when it occurs can pose significant clinical and diagnostic challenges for physicians treating these patients.We report case a 33-year-old Caucasian woman Mediterranean descent with newly diagnosed 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/computed (CT) scan-positive, early-stage involving cervical nodes who, despite having an excellent response to chemotherapy, had persistent 18F-FDG...
Abstract Introduction There is limited data on the effect of posture LVEF . The study aim was to determine any difference in using gated cardiac blood pool scanning ( GCBPS ) and T l ‐201 myocardial perfusion MPS prone or supine positions. Method In 50 patients undergoing evaluation for varying heart conditions, automated , end diastolic volume EDV ), systolic ESV measurements were obtained at rest during D iscovery NM 530 c GE H ealthcare). another patients, semi‐automated dual‐headed gamma...