Increase in life expectancy is among the most significant achievements of modern medicine. Currently, majority patients are elderly, being characterised by multimorbidity and frailty. Sarcopenia, a progressive generalized loss skeletal muscle mass strength, associated with reduced quality high risk adverse outcomes including disability death these patients. Age-related neuromuscular degeneration, decline circulating anabolic hormones, chronic inflammation oxidative stress considerably affect...

. The aim of the study was a quantitative assessment abdominal and epicardial depot visceral adipose tissue with use modern methods tomography in patients stable coronary heart disease (CHD). Material 88 were examined multislice computed magnetic resonance tomography. Results According to survey obesity observed 70.4% sample only 35.2% identified BMI. In CHD severity is not dependent on sex. Separating under standard boundary values fat area (130sm²) revealed significant differences layer...

One of the processes that accompany aging body and decline in quality life older people is sarcopenia or loss muscle tissue associated restriction mobility. The identification this condition patients at stage when there only an initial decrease mass without a strength great importance for determining cause disease timely start treatment. This review describes capabilities methods radiation diagnosis assessing quantity their shortcomings from standpoint verification dynamic observation...

Highlights . Taking into account the connection between increase in volume of myocardial adipose tissue and vessels with massive calcification coronary arteries heart disease, morphometry epicardial perivascular during routine tomographic examinations can be considered as a non-invasive technique for determining surrogate marker severe lesion. Aim To evaluate relationship artery (CA) morphometric parameters local fat depots patients disease (CHD). Methods 125 stable aged 59±8.9 years were...

Aim. To study the prevalence of musculoskeletal disorders in patients with stable coronary artery disease (CAD). Material and methods. Patients CAD (n=387) were included study. The subjects admitted to hospital for planned myocardial revascularization (ages 50-82). median age was 65 [59;69] years. Most sample consisted males - 283 (73.1%). 323 (83.5%) had arterial hypertension (AH), 57.1% history infarction, a quarter type 2 diabetes mellitus (DM). system identification sarcopenia accordance...

Measurement of neopterin in biological fluids is a sensitive and specific tool for detecting activation the T cell/macrophage system. Serum level, detected by radioimmunoassay, data from morphological investigations myocardium were compared 29 patients with clinical diagnosis dilated heart muscle disease. According to results endomyocardial biopsy (22 cases) autopsy (seven cases), 14 had features myocarditis, 13 cardiomyopathy two fibrotic subtype (DCMP). The mean level all (12 +/- 9 nM l-1)...

Highlights. Patients with coronary artery disease and age-related disorders (sarcopenia, osteopenic syndrome, osteosarcopenia) who underwent elective on-pump bypass grafting are at higher risk of developing cardiovascular complications, non-infectious death.Musculoskeletal in combination traditional predictors (age, diabetes mellitus, prior myocardial infarction stroke, cancer) factors for unfavorable prognosis postoperative period grafting. Aim. To assess patients (CAD) undergoing grafting,...

Aim. To assess the prevalence of frailty and describe clinical features frail patients with stable coronary artery disease (CAD). Methods. 387 admitted to hospital for elective primary bypass grafting (CABG) were recruited in study. Clinical data, demographic results instrumental examinations collected each subject. The screening prefrailty before surgery was performed using ’Age is not a hindrance’ questionnaire. processed IBM SPSS Statistics 26.0.0 software package. A value p ≤ 0.050...

Objective. To examine the relationships between measures of bone mineral density (BMD), coronary atherosclerosis, and artery calcification among men with ischemic heart disease (IHD). Materials Methods. Seventy-four angiographically documented IHD were assessed. BMD was measured by dual-energy absorptiometry defining T-score, radiopaque selective angiography analysis severity lesions using SYNTAX score, evaluating calcium score according to Agatston method. Depending on patients divided into...

Aim. To assess the relationship between prevalence of visceral obesity (VO) and severity coronary calcification (CC) in patients with verified artery disease (CAD). Materials methods. 125 CAD were examined. Assessment morphometric characteristics adipose tissue (VAT) CC was perform using multislice computed tomography (MSCT). The calcium index (CI) arteries (CA) determine by Agatston method. Statistical analysis Statistica 10.0. Results. VO detect 82 (65.6%) CAD. In presence VO, higher...

The most commonly atherosclerosis affects the aorta, coronary, iliac and extracranial arter ies . C alcification is a pathological manifestation o f vascular changes in atherosclerosis. At pathologic development of atherosclerotic plaques increasing proportion calcium compounds, included its composition. Study on relationship calcification coronary carotid arteries subject many studies. deposits found arterial wall proteins specific to bone matrix. No one was surprised by deterioration...

Objective . To estimate the density of calcium deposits atherosclerotic plaques coronary and carotid arteries in patients with diabetes mellitus (DM) type 2 using multislice computed tomography (MSCT). Material methods 251 multifocal atherosclerosis (MA) were examined MSCT. Determined equivalent (EDCD) plaque arteries. Results According to data MSCT MA irrespective concomitant was a high incidence calcification In Group 1 EDCD 0.235 (0.214; 0.254) mg/mm 3 , group - 0,219 (0,192; 0,242) 0.183...

The article provides a review of data on the use cardiac magnetic resonance imaging (CMRI) heart with contrast enhancement in determination structural and functional changes myocardium before revascularization procedures patients after infarct. possibility using results MRI assessment depth extent postinfarction cardiosclerosis forecast for recovery regional global left ventricular contractility restoration coronary blood flow. Determine value late to address appropriateness procedures....

See “Inflammaging in the pathogenesis of chronic non-communicable diseases”, Kim O. T. Opinion invited editor, pp. 54-55. The study osteosarcopenic obesity (OSO) patients with cardiovascular diseases (CVDs) recent years has caused a dis-cussion on common atherosclerosis, obesity, progressive loss skeletal and muscle mass. Are these processes independent age-related conditions or comorbidities links pathogenesis? aim this review was to analyze studies OSO CVDs. We used following electronic...

Objective. To assess the density of calcified substrate atherosclerotic plaques carotid arteries using data from computed tomography patients with multifocal atherosclerosis. Material and methods. In 251 verified atherosclerosis coronary arteries, a high prevalence angina pectoris, history myocardial infarction modifiable cardiovascular risk factors, multislice (MSCT) was performed to calcium index determine equivalent deposits (EDCD). A morphological sub-study material removed carried out...

<h3>Background:</h3> Thanks to the tactics of early myocardial revascularization and active secondary prevention, there is a tendency increase average age patients with atherosclerotic coronary lesions. At same time, muscle tissue deficiency in multivessel disease can affect both choice surgical tactics, considering possible complications, possibilities pre- rehabilitation. <h3>Objectives:</h3> To determine clinical portrait patient stable artery (CHD) concomitant impaired status using data...

Aim. Determination of the clinical and prognostic value equivalent density calcium deposits (EDCD) coronary arteries in patients with stable heart disease (CHD) concomitant osteopenic syndrome (OS) after artery bypass grafting (CABG), based on five-year follow-up. Materials methods. A prospective study included 393 CHD hospitalized for CABG. All underwent multispiral computed tomography to assess degree calcification EDCD, Х-ray absorptiometry. During observation we studied mortality adverse...

Th e aim of the research. To analyse structure complications in patients with coronary artery disease and different musculoskeletal disorders (MSD) undergoing elective bypass graft surgery (CABG) cardiopulmonary bypass. Material methods. From 2019 to 2020, a single-centre cohort study was conducted on 387 stable aged over 50 before CABG. The following MSD were assessed: sarcopenia, osteopenia, osteosarcopenia. Patients divided into four groups according type: group I included 52 (13.4 %) II...

<h3>Objectives</h3> To estimate parameters of calcium-phosphorus metabolism depending on the presence osteoporosis in patients with chronic ischemic heart disease. <h3>Methods</h3> The study included 66 male documented coronary disease and artery calcification. Average age: 59.8 (55; 70) years. Tacna bone mineral density (BMD) was measured by dual-energy x-ray absorptiometry at densitometere (g/cm³) indicators T-score femoral neck lumbar spine (vertebral bodies LI-LIV). determine...