A5068686902- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- IL-33, ST2, and ILC Pathways
- Cardiac Ischemia and Reperfusion
- Ultrasound and Hyperthermia Applications
- Adipokines, Inflammation, and Metabolic Diseases
- Hydrogen's biological and therapeutic effects
- Xenotransplantation and immune response
- 3D Printing in Biomedical Research
- Diabetes and associated disorders
- Advanced Glycation End Products research
Kyungpook National University Hospital
2021
Abstract BACKGROUND: High-fat diet-induced obesity is one of the major cause chronic renal failure. This obesity-related failure mainly caused by inflammatory processes. However, role anti-inflammatory cytokine interleukin (IL)-10 has not been researched intensively. METHODS: To evaluate effect IL-10 deficiency on failure, in vivo study was carried with four animal groups; (1) Low-fat dieted C57BL/6 mice, (2) knockout (KO) (3) High‐fat mice and (4) KO group. The analysis blood/urine...
Human adipose tissue includes useful substrates for regenerative medicine such as the extracellular matrix (ECM), but most perirenal fat is wasted after kidney surgery. Since a lot of can be procured kidney, we extracted ECM from human and optimized extraction process. To verify efficacy extraction, compared products in several steps. Perirenal was either finely homogenized or underwent crude manual dissection. The amount quantified with ELISA verification initial downsizing effect. validate...
Abstract The objective of this study was to select the optimal delipidation solvent for preparation human perirenal adipose tissue‐derived extracellular matrix (ECM). Human tissue can be obtained in large amounts during surgery, and it an alternative source ECM. Delipidation is essential procedure ECM preparation, because lipid strongly inhibits regeneration target tissue. Isopropanol has been widely used as a However, mostly composed nonpolar lipid, might more effective delipidation. We...
Background and Aim . Ischemia/reperfusion (I/R) injury, caused by acute kidney damage, causes histopathological alterations, tubule cell apoptosis, inflammation, oxidation, the loss of renal function. We evaluated protective effects against I/R injury beluga lentil pretreatment. Materials Methods Mice were divided into four groups: normal, untreated, low‐ (2 mg), high‐dose (8 mg) treatment groups. Beluga was orally administered for 2 weeks, followed bilateral ischemia 20 min reperfusion 30...