A5065159678- Plant Stress Responses and Tolerance
- Plant responses to water stress
- Polyamine Metabolism and Applications
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Plant nutrient uptake and metabolism
- Glycosylation and Glycoproteins Research
- Blood Coagulation and Thrombosis Mechanisms
- Immunotherapy and Immune Responses
- Bacterial Genetics and Biotechnology
- Cancer Immunotherapy and Biomarkers
- Immune cells in cancer
- Photosynthetic Processes and Mechanisms
- Parkinson's Disease Mechanisms and Treatments
- Spectroscopy Techniques in Biomedical and Chemical Research
- Amino Acid Enzymes and Metabolism
- Protease and Inhibitor Mechanisms
- Plant-Microbe Interactions and Immunity
- Peptidase Inhibition and Analysis
- Microbial Metabolism and Applications
- Meat and Animal Product Quality
- Plant responses to elevated CO2
- Chemokine receptors and signaling
- Plant tissue culture and regeneration
- Cancer Research and Treatments
- Molecular Biology Techniques and Applications
Teesside University
2019-2025
Aristotle University of Thessaloniki
2007-2025
Health & Life (Taiwan)
2025
University of Toronto
2017-2022
University Health Network
2017-2022
Health Net
2022
Cyprus University of Technology
2011-2021
Albert Einstein College of Medicine
2020
Vrije Universiteit Brussel
2018
Mount Sinai Hospital
2016
Reactive oxygen and nitrogen species are involved in a plethora of cellular responses plants; however, our knowledge on the outcomes oxidative nitrosative signaling is still unclear. To better understand how signals integrated to regulate adjustments external conditions, local systemic were investigated roots leaves sour orange plants (Citrus aurantium L.) after root treatment with hydrogen peroxide (H(2) O(2) ) or sodium nitroprusside (a nitric oxide donor), followed by NaCl stress for 8...
The interplay among polyamines (PAs) and reactive oxygen nitrogen species (RNS ROS) is emerging as a key issue in plant responses to salinity. To address this question, we analysed the impact of exogenous PAs [putrescine (Put), spermidine (Spd) spermine (Spm)] on oxidative nitrosative status citrus plants exposed partially reversed NaCl-induced phenotypic physiological disturbances. expression PA biosynthesis (ADC, SAMDC, SPDS SPMS) catabolism (DAO PAO) genes was systematically up-regulated...
Temperature extremes represent an important limiting factor to plant growth and productivity. The present study evaluated the effect of hydroponic pretreatment strawberry (Fragaria x ananassa cv. 'Camarosa') roots with H2S donor, sodium hydrosulfide (NaHS; 100 μM for 48 h), on response plants acute heat shock treatment (42°C, 8 h). Heat stress-induced phenotypic damage was ameliorated in NaHS-pretreated plants, which managed preserve higher maximum photochemical PSII quantum yields than...
Effects of water stress on plants have been well-documented. However, the combined responses to drought and rewatering their underlying mechanisms are relatively unknown. The present study attempts describe spatiotemporal alterations in physiology cellular status Medicago truncatula tissues that result from subsequently follow a period moderate deficit. Physiological processes damage levels were monitored roots leaves by determining lipid peroxidation levels, as well nitric oxide hydrogen...
Gliomas are the most common brain tumours with high-grade glioblastoma representing aggressive and lethal form. Currently, there is a lack of specific glioma biomarkers that would aid tumour subtyping minimally invasive early diagnosis. Aberrant glycosylation an important post-translational modification in cancer implicated progression. Raman spectroscopy (RS), vibrational spectroscopic label-free technique, has already shown promise diagnostics.RS was combined machine learning to...
Melanoma, the most lethal skin cancer type, occurs more frequently in Parkinson's disease (PD), and PD is frequent melanoma patients, suggesting mechanisms overlap. α-synuclein, a protein that accumulates brain, oncogene DJ-1, which associated with autosomal recessive forms, are both elevated cells. Whether this indicates progression or constitutes protective response remains unclear. We hereby investigated molecular through α-synuclein DJ-1 interact, novel biomarkers targets melanoma.
Nitric oxide (NO) is a bioactive molecule involved in numerous biological events that has been reported to display both pro-oxidant and antioxidant properties plants. Several reports exist which demonstrate the protective action of sodium nitroprusside (SNP), widely used NO donor, acts as signal plants responsible for expression regulation many enzymes. This study attempts provide novel insight into effect application low (100 μΜ) high (2.5 mM) concentrations SNP on nitrosative status...
Salinity constitutes one of the most important causes leading to severe reduction in plant yield. Several reports correlate accumulation polyamines plants with tolerance abiotic stress cues. The present study examined three Medicago truncatula genotypes differing sensitivities salinity (TN1.11, tolerant; Jemalong A17, moderately sensitive; TN6.18, sensitive), aim examining genotype-specific involvement polyamine metabolic pathway response salinity. was carried out leaves harvested 48 h after...
Biotic and abiotic stresses, such as fungal infection drought, cause major yield losses in modern agriculture. Kresoxim-methyl (KM) belongs to the strobilurins, one of most important classes agricultural fungicides displaying a direct effect on several plant physiological developmental processes. However, impact KM treatment salt drought stress tolerance is unknown. In this study we demonstrate that pre-treatment Medicago truncatula plants results increased protection stress. Foliar...
ABSTRACT Cancer and neurodegeneration are two major leading causes of morbidity death worldwide. At first sight, the fields do not seem to share much in common and, if anything, might be placed on opposite ends a spectrum. Although results excessive neuronal cell death, cancer emerges from increased proliferation resistance death. Therefore, one expect significant differences underlying pathophysiological mechanisms. However, more we deepen our understanding these types diseases, appreciate...
The aggregation of α-synuclein is crucial to the development Lewy body diseases, including Parkinson's disease and dementia with bodies. pathway typically involves a defined sequence nucleation, elongation, secondary exhibiting prion-like spreading. This study employed Raman spectroscopy machine learning analysis, alongside complementary techniques, characterize biomolecular changes during fibrillation purified recombinant wild-type protein. Monomeric was produced, purified, subjected 7-day...