Dechen Zhang

ORCID: 0000-0003-3984-7674
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Research Areas
  • Heat shock proteins research
  • Nanoplatforms for cancer theranostics
  • Endoplasmic Reticulum Stress and Disease
  • Advanced Nanomaterials in Catalysis
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Extracellular vesicles in disease
  • Nanopore and Nanochannel Transport Studies
  • Nanocluster Synthesis and Applications
  • Evacuation and Crowd Dynamics
  • Simulation and Modeling Applications
  • Nanoparticles: synthesis and applications
  • Smart Materials for Construction
  • Advanced Memory and Neural Computing
  • Quantum Dots Synthesis And Properties
  • Civil and Geotechnical Engineering Research
  • Wireless Power Transfer Systems
  • Safety and Risk Management
  • Coal Combustion and Slurry Processing
  • Immune Cell Function and Interaction
  • Peroxisome Proliferator-Activated Receptors
  • Infrared Target Detection Methodologies
  • Nanowire Synthesis and Applications
  • Long-Term Effects of COVID-19
  • Graphene and Nanomaterials Applications

Zhejiang University
2024

Houston Methodist
2016-2023

Jilin University
2017

Wuhan University
2015

As the major redox couple and nonprotein thiol source in human tissues, level of glutathione (GSH) has been a concern for its relation with many diseases. However, similar physical chemical properties interference molecules such as cysteine (Cys) homocysteine (Hcy) make discriminative detection GSH complex biological fluids challenging. Here we report novel surface-enhanced Raman scattering (SERS) platform, based on silver-nanoparticle-embedded porous silicon disks (PSDs/Ag) substrates...

10.1021/acsanm.7b00290 article EN ACS Applied Nano Materials 2017-12-18

A nanoscale metal–organic framework (MOF) based on zirconium, featuring the stacking of a layered structure, has been successfully synthesized. The linear dicarboxylic acid ligand FeTPY2 was built from unique coordination–dimerization strategy, through coordination terpyridyl group with ferrous ions. This approach offers methodology for extending length ligands, which is rarely employed in MOF design. Subsequently, this used making Zr-FeTPY2. deliberate incorporation cationic Fe2+ units...

10.1021/acsanm.3c05842 article EN ACS Applied Nano Materials 2024-02-07

Abstract Purpose: Triple-negative breast cancer (TNBC) is a clinically aggressive disease with poor prognosis. Conventional chemotherapeutics are generally able to shrink the tumor mass, but often fail completely eradicate stem–like cells (CSCs) that responsible for high risk of relapse and frequent metastases. In this study, we examined thermal sensibility CSCs, developed an approach enabled concurrent elimination both bulk investigated underlying mechanism. Experimental Design: We designed...

10.1158/1078-0432.ccr-17-3872 article EN Clinical Cancer Research 2018-06-19

Porous silicon nanodisks (PSD) were fabricated by the combination of photolithography and electrochemical etching silicon. By using PSD as a reducing agent, gold nanorods (AuNR) in situ synthesized nanopores PSD, forming PSD-supported-AuNR (PSD/AuNR) hybrid particles. The formation mechanism AuNR porous (pSi) was revealed exploring role pSi reducibility each chemical reaction. With support, exhibited stable morphology without toxic surface ligands (CTAB). PSD/AuNR particles showed enhanced...

10.1021/acsami.6b03008 article EN ACS Applied Materials & Interfaces 2016-04-28

Currently various types of aircraft booming and maturing, however, their long-time navigational capability should be improved urgently. This paper aims at studying laser power beaming, which includes the technology high-efficient photoelectric conversion APT(acquiring, pointing tracking) technology, to provide for flying UAV(unmanned aerial vehicles) improve flight endurance. The experiment testing different solar cells under conditions has been done choose cell highest rate find its most...

10.1117/12.2199235 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2015-10-15

<p>Supplementary Data Supplementary Methods Fig. S1. Increased CD44+CD24-ESA+ cell subpopulation in (A) SUM159 and (B) MDA-MB-231 cells after docetaxel treatment. *, p< 0.05; **, 0.01 (compared to untreatment controls). Analysis of apoptotic (C) (D) 24 hours were treated with DTX for 8 followed by hyperthermia at 43ï,°C 5 min. 0.01. The mean standard deviations calculated from three replicates. S2. NIR-triggered heat generation AuPSMs. Different efficiency on different size Au...

10.1158/1078-0432.22470363 preprint EN cc-by 2023-03-31

<p>Supplementary Data Supplementary Methods Fig. S1. Increased CD44+CD24-ESA+ cell subpopulation in (A) SUM159 and (B) MDA-MB-231 cells after docetaxel treatment. *, p< 0.05; **, 0.01 (compared to untreatment controls). Analysis of apoptotic (C) (D) 24 hours were treated with DTX for 8 followed by hyperthermia at 43ï,°C 5 min. 0.01. The mean standard deviations calculated from three replicates. S2. NIR-triggered heat generation AuPSMs. Different efficiency on different size Au...

10.1158/1078-0432.22470363.v1 preprint EN cc-by 2023-03-31

<div>Abstract<p><b>Purpose:</b> Triple-negative breast cancer (TNBC) is a clinically aggressive disease with poor prognosis. Conventional chemotherapeutics are generally able to shrink the tumor mass, but often fail completely eradicate stem–like cells (CSCs) that responsible for high risk of relapse and frequent metastases. In this study, we examined thermal sensibility CSCs, developed an approach enabled concurrent elimination both bulk investigated underlying...

10.1158/1078-0432.c.6527535.v1 preprint EN 2023-03-31

<div>Abstract<p><b>Purpose:</b> Triple-negative breast cancer (TNBC) is a clinically aggressive disease with poor prognosis. Conventional chemotherapeutics are generally able to shrink the tumor mass, but often fail completely eradicate stem–like cells (CSCs) that responsible for high risk of relapse and frequent metastases. In this study, we examined thermal sensibility CSCs, developed an approach enabled concurrent elimination both bulk investigated underlying...

10.1158/1078-0432.c.6527535 preprint EN 2023-03-31

Scavenging excessively secreted cytokines from plasma is vital for treating cytokine storm syndrome (CSS). Therefore, appropriate adsorbent materials are highly desired efficient and selectively capturing the cytokines. For this purpose, injectable porous silicon particles (PSPs) designed as scavenging adsorbents. The fabricated PSP features high porosity large pore volume specific surface area. Polyethylene glycol coated on outer of a longer body circulation time, while antibodies...

10.1002/anbr.202300037 article EN cc-by Advanced NanoBiomed Research 2023-09-03

Injectable Nanoparticles Appropriate materials for the efficient and selective capturing of plasma cytokines are urgently needed. In article number 2300037, Jianliang Shen, Xuewu Liu, co-workers design injectable porous silicon particles (PSPs) as scavenging adsorbents. The fabricated PSPs feature high porosity large pore volume specific surface area, a longer body circulation time. To facilitate recognition targeting biomacromolecules, antibodies immobilized on interior PSPs.

10.1002/anbr.202370101 article EN cc-by-nc Advanced NanoBiomed Research 2023-10-01
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