Lirui Cheng

ORCID: 0000-0003-3994-8782
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About
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Research Areas
  • Plant-Microbe Interactions and Immunity
  • Plant Disease Resistance and Genetics
  • Genetic Mapping and Diversity in Plants and Animals
  • Plant Pathogenic Bacteria Studies
  • Plant Virus Research Studies
  • Plant Genetic and Mutation Studies
  • Genetically Modified Organisms Research
  • Plant Pathogens and Resistance
  • Legume Nitrogen Fixing Symbiosis
  • Plant tissue culture and regeneration
  • Transgenic Plants and Applications
  • Plant Gene Expression Analysis
  • Advances in Cucurbitaceae Research
  • Spectroscopy and Chemometric Analyses
  • Wheat and Barley Genetics and Pathology
  • Mobile Health and mHealth Applications
  • Genetic and phenotypic traits in livestock
  • GABA and Rice Research
  • Diabetic Foot Ulcer Assessment and Management
  • Genetics and Plant Breeding
  • Nematode management and characterization studies
  • Plant Parasitism and Resistance
  • Autophagy in Disease and Therapy
  • Diabetes Management and Research
  • Genomics, phytochemicals, and oxidative stress

Tobacco Research Institute
2020-2025

Chinese Academy of Agricultural Sciences
2020-2025

University of Shanghai for Science and Technology
2024

Root exudates serve as chemical signaling molecules that regulate rhizosphere interactions and control soil-borne diseases. The between plants the soil microbiome play dynamic crucial roles in regulating resistance of to biotic stress. However, specific many root plant pathogens remain unclear. exudate methyl ferulate, a naturally occurring relatively non-toxic antifungal agent, has been applied postharvest preserve foodstuffs not used disease control. This study investigated role ferulate...

10.1186/s40168-024-02008-3 article EN cc-by-nc-nd Microbiome 2025-01-31

Tobacco black shank caused by Phytophthora nicotianae is a serious disease in tobacco cultivation. We found that naringenin key factor causes different sensitivity to P. between resistant and susceptible tobacco. The level of basal flavonoids was distinct from Of all with content, showed the best antimicrobial activity against mycelial growth sporangia production vitro. However, very low or no other plant pathogens. induced not only accumulation reactive oxygen species, but also expression...

10.1111/mpp.13255 article EN Molecular Plant Pathology 2022-09-12

Nicotiana tabacum is an allotetraploid hybrid of sylvestris and tomentosiformis a model organism in genetics. However, features subgenome evolution, expression coordination, genetic diversity complex traits regulation N. remain unresolved. Here we present chromosome-scale assemblies for all three species, genotype phenotypic data 5,196 germplasms. Chromosome rearrangements epigenetic modifications are associated with genome evolution coordination following polyploidization. Two subgenomes...

10.1038/s41588-025-02126-0 article EN cc-by-nc-nd Nature Genetics 2025-03-26

The TIFY gene family plays an essential role in plant development and abiotic biotic stress responses. In this study, genome-wide identification of members tobacco their expression pattern analysis response to Ralstonia solanacearum infection were performed. A total 33 genes identified, including the TIFY, PPD, ZIM&ZML JAZ subfamilies. Promoter results indicated that a quantity light-response, drought-response, SA-response JA-response cis-elements exist promoter regions. exhibited expansion...

10.1016/j.ygeno.2024.110823 article EN cc-by-nc Genomics 2024-03-14

Bacterial wilt (BW) caused by Ralstonia solanacearum is a globally prevalent bacterial soil-borne disease. In this study, transcriptome sequencing were subjected to roots after infection with the R. in resistant and susceptible tobacco variety. DEGs that responded both contributed pectinase peroxidase development enriched plant hormone signal transduction, transduction MAPK signalling pathway KEGG terms. Core response cell wall, membrane, abscisic acid ethylene qRT-PCR indicated...

10.1016/j.ygeno.2024.110784 article EN cc-by-nc-nd Genomics 2024-01-09

Abstract Background Tobacco mosaic virus (TMV) is a widely distributed viral disease that threatens many vegetables and horticultural species. Using the resistance gene N which induces hypersensitivity reaction, common strategy for controlling this in tobacco ( Nicotiana tabacum L . ). However, gene-mediated has its limitations, consequently, identifying genes from resistant germplasms developing cultivars an ideal damage caused by TMV. Results Here, we identified highly TMV-resistant...

10.1186/s12870-024-04744-y article EN cc-by BMC Plant Biology 2024-01-24

Multiparent Advanced Generation Inter-Cross (MAGIC) population is an ideal genetic and breeding material for quantitative trait locus (QTL) mapping molecular breeding. In this study, a MAGIC derived from eight tobacco parents was developed. Eight 560 homozygous lines were genotyped by 430K single-nucleotide polymorphism (SNP) chip assay phenotyped nicotine content under different conditions. Four QTLs associated with detected genome-wide association (GWAS), one major QTL, named qNIC7-1,...

10.3389/fpls.2022.1086950 article EN cc-by Frontiers in Plant Science 2023-01-10

Agronomic traits such as plant height (PH), leaf number (LN), length (LL), and width (LW), which are closely related to yield quality, important in tobacco (Nicotiana tabacum L.). To identify quantitative trait loci (QTLs) associated with agronomic tobacco, 209 recombinant inbred lines (RILs) 537 multiparent advanced generation intercross (MAGIC) were developed. The biparental RIL MAGIC genotyped using a 430 K single-nucleotide polymorphism (SNP) chip assay, their repeatedly evaluated under...

10.3389/fpls.2022.878267 article EN cc-by Frontiers in Plant Science 2022-06-06

Introduction Plant bacterial wilt is an important worldwide disease caused by Ralstonia solanacearum which a complex of species. Methods In this study, we identified and sequenced the genome R. strain gd-2 isolated from tobacco. Results Strain was as species (RSSC) phylotype I sequevar 15 exhibited strong pathogenicity to The size 5.93 Mb, including chromosomes (3.83 Mb) megaplasmid (2.10 Mb). Gene prediction results showed that 3,434 1,640 genes were in plasmids, respectively. Comparative...

10.3389/fmicb.2024.1335081 article EN cc-by Frontiers in Microbiology 2024-03-14

Ralstonia solanacearum species complex (RSSC) is a diverse group of plant pathogens that attack wide range hosts and cause devastating losses worldwide. In this study, we conducted comprehensive analysis 131 RSSC strains to detect their genetic diversity, pathogenicity, evolution dynamics. Average nucleotide identity was performed explore the genomic relatedness among these strains, finally obtained an open pangenome with 32,961 gene families. To better understand also series analyses...

10.3389/fmicb.2022.854792 article EN cc-by Frontiers in Microbiology 2022-05-06

Abstract Background: At present, the distinctness, uniformity, and stability (DUS) testing of flue-cured tobacco ( Nicotiana tabacum L.) depends on field morphological identification, which is problematic in that it intensive, time-consuming, susceptible to environmental impacts. In order improve efficiency accuracy DUS testing, development a molecular marker-based method for genetic diversity identification urgently needed. Results: total, 91 simple sequence repeats (SSR) markers with clear...

10.21203/rs.2.20461/v2 preprint EN cc-by Research Square (Research Square) 2020-03-11

Abstract Phenotypic plasticity is the property of a given genotype to produce multiple phenotypes in response changing environmental conditions. Understanding genetic basis phenotypic and establishing predictive model highly relevant for future agriculture under climate. Here, we investigated leaf width tobacco MAGIC population across four different environments. Environmental changes not only resulted differences mean but also plasticity. A total 45 QTL were identified, including 14 43...

10.1101/2024.05.05.592603 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-05-07

Solanesol, which accumulates predominantly in the leaves of tobacco plants, has medically important bioactive properties. To investigate genetic basis solanesol (Nicotiana tabacum), contents 222 accessions, 206 individuals from an N. tabacum Maryland609 (low-solanesol) × K326 (high-solanesol) F2 population and their corresponding F1 self-pollinations, were determined using ultra-performance liquid chromatography. Genome-wide quantitative trait locus (QTL) association analysis performed to...

10.3390/agronomy14071370 article EN cc-by Agronomy 2024-06-26

TOBAMOVIRUS MULTIPLICATION 1 (TOM1) and its homolog 3 (TOM3) play a prominent role in the multiplication of tobacco mosaic virus (TMV) higher plants. Although homologs NtTOM1/TOM3 genes have been identified several plant species, little is known about characteristics functions at genome-wide level (Nicotiana tabacum L.).

10.1186/s12870-024-05632-1 article EN cc-by-nc-nd BMC Plant Biology 2024-10-10

Black shank, caused by the oomycetes Phytophthora nicotianae, is destructive to tobacco, and this pathogen highly pathogenic many solanaceous crops. P. nicotianae well adapted high temperatures; therefore, research on gaining importance in agriculture worldwide because of global warming. nicotianae-resistant varieties tobacco plants are commonly screened inoculation with oat grains colonized monitoring for disease symptoms. However, it difficult quantify intensity since accurate crucial...

10.3791/63054 article EN Journal of Visualized Experiments 2022-04-15

The aim of this study is to evaluate the effectiveness a smart non-invasive blood glucose monitor prototype during pregnancy through clinical validation. utilizes near-infrared spectroscopy combined with AI big data analysis photoelectric volumetric pulse wave achieve monitoring in women pregnancy. research team developed that employs sensing chip, effectively overcoming problems weak signals and individual differences monitoring. user experience enhanced by visualizing test results on...

10.12455/j.issn.1671-7104.240106 article EN PubMed 2024-09-30

Nicotiana tabacum is a model organism in plant genetics and synthetic biology. Challenged by the large complex polyploid genome, its genomic features, genetic diversity regulation of many traits remain unknown. Here, we present nearly complete chromosome-scale assembly N. GenBank-scale sequencing phenotyping data from 5196 germplasms. Homoeologous exchange epigenetic remodelling likely contributed to genome stabilization subgenome coordination following polyploidization. Geography at...

10.2139/ssrn.4414870 preprint EN 2023-01-01

Bacterial wilt (BW) caused by Ralstonia solanacearum is a globally prevalent bacterial soil-borne disease. In this study, transcriptome sequencing were subjected to roots after infection with the R. in resistant and susceptible tobacco variety. DEGs that responded both contributed pectinase peroxidase development enriched plant hormone signal transduction, transduction MAPK signalling pathway KEGG terms. Core response cell wall, membrane, abscisic acid ethylene qRT-PCR indicated...

10.2139/ssrn.4619466 preprint EN 2023-01-01

The TIFY gene family plays an essential role in plant development, abiotic and biotic stress responses. In this study, genome-wide identification of tobacco expression patterns analysis response to Ralstonia solanacearum were performed. A total 33 genes identified, including TIFY, PPD, ZIM&ZML JAZ subfamilies. Promoter results indicated that quantities cis-elements exist promoter regions. NtTIFY exhibited expansion caused redundancy resulting from ploidy change. Additionally, most NtTIFYs...

10.2139/ssrn.4663191 preprint EN 2023-01-01

Abstract Background: At present, the distinctness, uniformity, and stability (DUS) testing of flue-cured tobacco ( Nicotiana tabacum L.) depends on field morphological identification, which is problematic in that it intensive, time-consuming, susceptible to environmental impacts. In order improve efficiency accuracy DUS testing, development a molecular marker-based method for genetic diversity identification urgently needed. Results: total, 91 simple sequence repeats (SSR) markers with clear...

10.21203/rs.2.20461/v4 preprint EN cc-by Research Square (Research Square) 2020-08-13

Abstract Background: At present, the distinctness, uniformity, and stability (DUS) testing of flue-cured tobacco ( Nicotiana tabacum L.) depends on field morphological identification, which is problematic in that it intensive, time-consuming, susceptible to environmental impacts. In order improve efficiency accuracy DUS testing, development a molecular marker-based method for genetic diversity identification urgently needed. Results: total, 91 simple sequence repeats (SSR) markers with clear...

10.21203/rs.2.20461/v3 preprint EN cc-by Research Square (Research Square) 2020-08-05

Abstract Multiparent Advanced Generation Inter-Cross (MAGIC) populations are ideal genetic and breeding materials for quantitative trait locus (QTL) mapping molecular breeding. In this study, a MAGIC population derived from eight tobacco parents was developed. Eight 560 homozygous lines were genotyped by 430K single-nucleotide polymorphism (SNP) chip assay phenotyped nicotine content under different conditions. Four QTLs associated with detected genome-wide association (GWAS), one major QTL,...

10.21203/rs.3.rs-1718251/v1 preprint EN cc-by Research Square (Research Square) 2022-07-11

Black shank, caused by the oomycetes Phytophthora nicotianae, is destructive to tobacco, and this pathogen highly pathogenic many solanaceous crops. P. nicotianae well adapted high temperatures; therefore, research on gaining importance in agriculture worldwide because of global warming. nicotianae-resistant varieties tobacco plants are commonly screened inoculation with oat grains colonized monitoring for disease symptoms. However, it difficult quantify intensity since accurate crucial...

10.3791/63054-v article EN Journal of Visualized Experiments 2022-04-15
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