Wei He

ORCID: 0000-0003-3997-4526
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About
Contact & Profiles
Research Areas
  • Epigenetics and DNA Methylation
  • Plant Genetic and Mutation Studies
  • Cancer-related gene regulation
  • Metabolomics and Mass Spectrometry Studies
  • Genomics and Phylogenetic Studies
  • Cancer-related molecular mechanisms research
  • Plant Stress Responses and Tolerance
  • Heavy Metals in Plants
  • Galectins and Cancer Biology
  • Machine Learning in Bioinformatics
  • Heavy metals in environment
  • Phytase and its Applications
  • Coal and Its By-products
  • GABA and Rice Research
  • RNA modifications and cancer
  • Bladder and Urothelial Cancer Treatments
  • Circular RNAs in diseases
  • Studies on Chitinases and Chitosanases
  • Urological Disorders and Treatments
  • Prostate Cancer Treatment and Research

Ministry of Natural Resources
2024

Shandong Agricultural University
2022

Fudan University
2018-2021

Huadong Hospital
2021

First Affiliated Hospital of Zhengzhou University
2015

Prostate cancer is among the top mortality factors in male around world. Long non-coding RNAs (lncRNAs) have been shown to play crucial roles tumor biology and immunology. However, lncRNA-immune interactions not yet examined prostate cancer. Here, we performed integrated analysis characterize through multidimensional aspects, including immune-related hallmarks, immunogenomic signatures, biological processes, immune cells, checkpoints. We dissected dysregulation of lncRNAs their clinical...

10.3389/fcell.2021.641891 article EN cc-by Frontiers in Cell and Developmental Biology 2021-02-16

The aim of the present study was to investigate correlation between expression DNA (cytosine‑5)‑methyltransferase 1 (DNMT1), glutathione S‑transferase‑P1 (GSTP1) and adenomatous polyposis coli (APC), methylation status GSTP1 APC in prostate cancer (PCa) benign prostatic hyperplasia (BPH), examine its clinical significance. Immunohistochemistry reverse transcription‑polymerase chain reaction (RT‑PCR) used detect DNMT1, 56 samples PCa tissue 10 BPH tissue. Methylation‑specific‑PCR CpG island...

10.3892/mmr.2015.3402 article EN cc-by-nc Molecular Medicine Reports 2015-03-03

Foxtail millet (Setaria italica L.) is an important cereal for managing future water scarcity and ensuring food security, due to its strong drought salt stress resistance owing developed root system. However, the molecular responses of foxtail leaves are largely unknown. In this study, seeds 104 accessions were subjected 0.17 mol·L-1 NaCl during germination, various germination-related parameters analyzed derive 5 salt-sensitive 13 salt-tolerant accessions. Hong Gu 2000 Pu Huang Yu most...

10.3390/plants11141864 article EN cc-by Plants 2022-07-18

Abstract Archaeal membrane lipids are markedly distinct from those in bacteria and eukaryotes, serving as unique biomarkers for unraveling their ecological biogeochemical roles. Recent advancements lipidomics have facilitated detailed cellular-level characterizations of lipid compounds. However, the lack a comprehensive dedicated database has severely limited large-scale, high-throughput investigations archaeal lipids. We present ArchLips, containing 218,868 silico molecular structures...

10.1101/2025.05.05.652033 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2025-05-06

Abstract Lung adenocarcinoma (LUAD) is a common diagnosed disease with high‐mortality rate, and its prognostic implications are under discovered. DNA methylation aberrations not only an important event for dysregulation of gene expression during tumorigenesis but also revolution in epigenetics by identifying key biomarkers multiple cancers. In this study, we analyzed status 485 578 CpG sites RNA‐seq transcriptomes 20 532 genes 1095 LUAD samples TCGA database. The association between the...

10.1002/cam4.1834 article EN cc-by Cancer Medicine 2018-10-23
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