A5005071849- Spine and Intervertebral Disc Pathology
- Anatomy and Medical Technology
- Spinal Fractures and Fixation Techniques
- Bone and Joint Diseases
- Orthopaedic implants and arthroplasty
- Cervical and Thoracic Myelopathy
- Erythrocyte Function and Pathophysiology
- Blood properties and coagulation
- Psychosomatic Disorders and Their Treatments
- Collaborative Teaching and Inclusion
- Orthopedic Infections and Treatments
- Scoliosis diagnosis and treatment
- Mechanical Engineering and Vibrations Research
- Mindfulness and Compassion Interventions
- Tribology and Lubrication Engineering
- Teacher Education and Leadership Studies
- Gear and Bearing Dynamics Analysis
- Palliative Care and End-of-Life Issues
- Cell Adhesion Molecules Research
- Pregnancy-related medical research
- Psychedelics and Drug Studies
- Cellular transport and secretion
- Connective tissue disorders research
- Reflective Practices in Education
- Hip and Femur Fractures
University of Arkansas for Medical Sciences
2017-2024
University of Georgia
2002
Mechanical loading is essential for bone growth and homeostasis, with osteocytes considered the primary mechanosensors. Deleting mechanosensitive ion channel Piezo1 from Dmp1-Cre-targeted cells, which include both osteoblasts osteocytes, resulted in reduced mass impaired skeletal responses to mechanical stimuli. To specifically isolate Piezo1's role we used Sost-Cre mice generate deletion exclusively mature osteocytes. These exhibited lower mineral density, decreased cancellous mass,...
Abstract The relaxin/insulin-like family peptide receptor 2 (RXFP2) belongs to the of class A G-protein coupled receptors (GPCRs) and it is only known target for insulin-like factor 3 (INSL3). importance this ligand-receptor pair in development gubernacular ligament during transabdominal phase testicular descent well established. More recently, RXFP2 has been implicated maintaining healthy bone formation. In report, we describe discovery a small molecule series agonists. These compounds are...
Smith McCort (SMC) dysplasia is a rare, autosomal recessive, osteochondrodysplasia that can be caused by pathogenic variants in either RAB33B or DYM genes. These genes codes for proteins are located at the Golgi apparatus and have role intracellular vesicle trafficking. We generated mice carry Rab33b disease-causing variant, c.136A>C (p.Lys46Gln), which identical to of members from consanguineous family diagnosed with SMC. In male 4 months age, variant mild increase trabecular bone thickness...
Surface strains recorded from multiple rosette gauges at different sites on the left forehooves of horses and donkeys during walks 1.8 m/s are discussed. The strain pattern wall was manipulated by adding 12 mm cleat wedges to heels horseshoes. Principal were repeatable for each gauge site situation an individual. Substantial inter-individual variation existed. Peak principal always in compression. Under normal circumstances (no cleats attached) peak order 1000-3000 /spl mu//spl epsi/,...
This was a biomechanical comparison study.The objective of this study is to evaluate the mechanical properties 3 posterior spinal fusion assemblies commonly used cross cervicothoracic junction.When cervical fusions are extended into thoracic spine, an instrumentation transition often utilized. The rod (3.5 mm) can continue using screws designed accept rods. Alternatively, traditional may be rods (5.5 mm). requires use 3.5-5.5 mm or separate 5.5 and connector fix 3.5 together. Fusion success...
Gross anatomy courses that incorporate the use of cadaveric specimens feature concepts death and mortality in addition to structures human body. Although is often a poignant topic for various religious traditions, concept religion seldom considered courses. In fact, number traditions consider dead with utmost respect deem dissection practices be somewhat disrespectful or taboo. Since Liaison Committee on Medical Education Standards require medical students acquire cultural competence belief...
INTRODUCTION Previous work has shown that students know more information about their donors, such as first names, tend to do better in gross anatomy courses (Talarico, 2013). Yet, there are little no data of how student‐chosen names may affect student performance or experience. AIM Assess choice name cadavers impacts and experience a medical course. METHODS First‐year volunteers (n=151) at the University Arkansas for Medical Sciences were administered survey inquiring dissection course...
ABSTRACT IMPACT: A comparative evaluation of the mechanical properties commonly used posterior spinal fusion assemblies will allow surgeons to choose an assembly based on desired properties. The results better inform surgical decision making and may lead improved patient outcomes. OBJECTIVES/GOALS: objective this study is evaluate compare three cross cervicothoracic junction. Fusion success depends immobilization vertebrae. improve METHODS/STUDY POPULATION: Three titanium alloy intended...