A5101490418- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Neuroendocrine Tumor Research Advances
- Gastric Cancer Management and Outcomes
- Allergic Rhinitis and Sensitization
- Gastrointestinal disorders and treatments
- Gastrointestinal Tumor Research and Treatment
- Dermatology and Skin Diseases
- Asthma and respiratory diseases
- Meningioma and schwannoma management
- Pregnancy and preeclampsia studies
- Renal cell carcinoma treatment
- Cancer Genomics and Diagnostics
- Cancer Diagnosis and Treatment
- Anesthesia and Pain Management
- Cancer Mechanisms and Therapy
- Epigenetics and DNA Methylation
- Cytokine Signaling Pathways and Interactions
- 14-3-3 protein interactions
- Advanced Thermoelectric Materials and Devices
- Diet and metabolism studies
- Neurofibromatosis and Schwannoma Cases
- Esophageal and GI Pathology
- Hedgehog Signaling Pathway Studies
Tianjin University of Traditional Chinese Medicine
2025
Affiliated Hospital of Jiangsu University
2024
Jiangsu University
2024
Eye & ENT Hospital of Fudan University
2024
North University of China
2024
Second Affiliated Hospital of Xi'an Jiaotong University
2024
Shandong University
2023
Beijing Shijitan Hospital
2021-2022
Capital Medical University
2007-2022
Peking University
2010-2021
The long noncoding RNA (lncRNA) H19 has been proven to be overexpressed in human pancreatic ductal adenocarcinoma (PDAC). H19-induced PDAC cell proliferation is cycle-dependent by modulating E2F-1. However, the mechanism of how regulates E2F-1 remains unclear. In this study, we investigated expression miR-675 tumours and cells, biological function possible relationship among H19, As a transcript first exon level was negatively correlated with microdissected tissues (r=-0.0646, P=0.001)....
Objective Gestational diabetes mellitus (GDM) is a serious threat to maternal and child health. However, there isn’t standard predictive model for the disorder in early pregnancy. This study investigate association of blood indexes with GDM establishes practical pregnancy GDM. Methods prospective cohort enrolling 413 pregnant women department Obstetrics Gynecology Shanghai General Hospital from July 2020 April 2021.A total 116pregnantwomen were diagnosed during follow-up. Blood samples...
Abstract Background Paediatric orthopaedics is a significant and difficult for undergraduate students to master. During the COVID-19 pandemic, we used WeChat platform combine advantages offered by problem-based learning (PBL), case-based (CBL) paper review teaching methods establish new blended online model demonstrated its feasibility effectiveness. Objective This study aims demonstrate effectiveness of pedagogical method that uses combines PBL, CBL review. Methods We enrolled 22...
This study aims to investigate the pathogenesis of precancerous lesions gastric cancer(PLGC) and explore potential molecular mechanism Weifuchun Capsules(WFC) in treating PLGC via nuclear factor-κB(NF-κB)/NOD-like receptor protein 3(NLRP3) inflammasome signaling pathway. Ninety male SPF-grade Wistar rats were randomized into a normal feeding group modeling group. The received regular diet, while was subjected disease-syndrome combined PLGC. Specifically, had free access water containing 120...
Here we presented the initial experience of clipping aneurysms using fully endoscopic techniques and aimed to evaluate safety feasibility for aneurysms. This was a retrospective single-center study in which patients were scheduled undergo aneurysm techniques. We collected patients' records, radiological neuroimaging, aneurysm-related variables surgical procedures detail, as well postoperative outcomes. All followed up neurological examinations computed tomography (CT) angiography (CTA)...
The special anatomical position accounts for unusual clinicopathological features of uncinate process cancer. This study aimed to compare patients with cancer non-uncinate pancreatic head Total 160 were enrolled and classified into two groups: We found that the ratio vascular invasion was significantly higher in than In addition, rate R1 resection Furthermore, median disease-free survival (11 months vs. 15 months, p=0.043) overall (15 19 p=0.036) after R0 lower Locoregional recurrence more...
To validate the 8th edition of American Joint Committee on Cancer (AJCC) staging system for pancreatic ductal adenocarcinoma (PDAC) in a Chinese cohort radically resected patients and to develop refined PDAC.Data were collected from China Pancreas Data Center (CPDC) with PDAC 2016 2017, cancer-specific survival (CSS) was evaluated using Kaplan-Meier method log-rank test. Univariate multivariate analyses based Cox regression performed identify prognostic factors. The recursive partitioning...
Long lasting and unbearable abdominal pain is the most common symptom of chronic pancreatitis (CP). This study aimed to evaluate surgical options for control pancreatic based on anatomical morphological changes.A retrospective review patients who underwent surgery treatment in Peking University First Hospital between January 2000 December 2017 was performed. The included modified Puestow procedure, Frey Beger pancreaticoduodenectomy (PD) or pylorus preserving (PPPD), distal pancreatectomy...
Abstract Background There has been research about the prevalence and risk factors of eczema, hay fever, asthma in children, but little is known these conditions adults China. Objectives To explore adult eczema/atopic dermatitis (AD) its northern Methods A cluster sampling randomized population-based survey was conducted using a face-to-face questionnaire combined with skin prick tests ten common aeroallergens including nine pollen allergens Dermatophagoides pteronyssinu (Dp) allergen. The...
There is a close association between diet and abdominal pain; however, relationship inflammatory characteristics of pain has not been characterized yet.
Abstract Objective: To evaluate the risk factors for disease-free survival (DFS) of pancreatic ductal adenocarcinoma (PDAC) patients after surgery, and to validate clinical applicability prognostic stratification 8th edition American Joint Committee on Cancer (AJCC) staging system. Methods: A cohort 185 with PDAC who underwent surgical resection in General Surgery Department Peking University First Hospital from January 2010 December 2017 was enrolled retrospectively. The clinicopathological...
Specific immunotherapy is the only effective etiological treatment for allergic rhinitis, but subcutaneous has a slow onset and poor compliance. Predicting clinical efficacy of in advance can reduce unnecessary medical costs resource waste. This study aimed to identify metabolites that could predict on seasonal rhinitis by serum metabolomics.Patients (n = 43) with Artemisia sieversiana pollen were enrolled treated one year. Patients divided into ineffective group 10) 33) according...
Background Tissue factor (TF) is overexpressed in many malignant tumours and linked to the pathogenesis prognosis of such malignancies. In vitro studies have proved that reduced expression TF has inhibitory effect on angiogenesis cell proliferation tumour. Therefore, suppression been raised as a possible treatment for tumours. Here we investigated celecoxib induced by tumour necrosis α (TNFα) PANC-1 cells molecular mechanism underlying effect. Methods Various doses solution were added...
This work aimed to study the effect of nanoscale graphene oxide (NGO) and probiotics on expression β -catenin (chain protein) in pediatric osteosarcoma (OSA) cells. Ninety patients with OSA were taken as research object, who classified into control group, GO group. Their tumor tissues collected cultured. NGO materials prepared by adding N, N -dimethylformamide solvent graphite powder. The group was interfered normal saline, treated NGO, mixed bacterial solution. results showed that mRNA...
Heatstroke usually occurs in summer during heat waves, and few cases occur winter. We report the case of a 26-year-old man who went through multiple organ dysfunction after sauna January, finally was diagnosed as heatstroke.