A5100446279- Photosynthetic Processes and Mechanisms
- Algal biology and biofuel production
- Spectroscopy and Quantum Chemical Studies
- Biocrusts and Microbial Ecology
- Proteins in Food Systems
- Protein Hydrolysis and Bioactive Peptides
- Advanced Photocatalysis Techniques
- Collagen: Extraction and Characterization
- Silk-based biomaterials and applications
- Hydrogen's biological and therapeutic effects
- TiO2 Photocatalysis and Solar Cells
- Seaweed-derived Bioactive Compounds
- Hydrogels: synthesis, properties, applications
- Photoreceptor and optogenetics research
- Pickering emulsions and particle stabilization
- Electrospun Nanofibers in Biomedical Applications
- Porphyrin and Phthalocyanine Chemistry
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Enzyme Catalysis and Immobilization
- Periodontal Regeneration and Treatments
- Effects of Radiation Exposure
- Glutathione Transferases and Polymorphisms
- Plant and animal studies
- Advanced biosensing and bioanalysis techniques
Yantai Institute of Coastal Zone Research
2016-2025
Chinese Academy of Sciences
2016-2025
Shandong Academy of Chinese Medicine
2023-2025
Dali University
2025
Shandong University of Traditional Chinese Medicine
2023-2025
Xihua University
2025
Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
2025
Sun Yat-sen University
2025
Shandong University
2024
Shaanxi Provincial People's Hospital
2024
Drug-delivery systems (DDSs) are designed to deliver drugs their specific targets minimize toxic effects and improve susceptibility clearance during targeted transport. Peptides have high affinity, low immunogenicity, simple amino acid composition, adjustable molecular size; therefore, most peptides can be coupled via linkers form peptide-drug conjugates (PDCs) act as active pro-drugs. PDCs widely thought promising DDSs, given ability drug bio-compatibility physiological stability....
Nano/micro-sized titania powders were prepared by a hydrothermal method using an aqueous solution of TiCl4 as precursor. The influence the concentration on formation, phase, morphology, and grain size products was investigated at various reaction temperatures times. Increasing favored formation rutile type TiO2. When [TiCl4] < 0.5 mol dm−3, mixture anatase powders, percentage in all crystalline varied with time. = product pure powder. powder related to based nucleation growth theory...
Abstract The lifetime of electronic coherences found in photosynthetic antennas is known to be too short match the energy transfer time, rendering coherent mechanism inactive. Exciton-vibrational coherence time excitonic dimers which consist two chromophores coupled by excitation interaction, can however much longer. Uncovering for sustained a noisy biological environment challenging, requiring use simpler model systems as proxies. Here, via two-dimensional spectroscopy experiments, we...
Phycocyanin (PC) is a type of natural protein in algae with antioxidant and anti-inflammatory properties. However, the protective effect PC on hepatic damage induced by X-ray remains unknown. Male C57BL/6 mice were gavaged 200mg/kg for consecutive 7 days before or after radiation. The blood samples tissues collected 1 radiation exposure. Pretreatment treatment decreased significantly levels alanine aminotransferase (ALT), aspartate aminotransferase(AST) plasma. Histological evaluation...
Effective control of acute wound hemorrhage caused by battlefields, car accidents, natural disasters can highly improve patients' survival rates. Nevertheless, hemostatic materials on present market have various defects and limitations. This study utilizes tilapia to extract macromolecular type I collagen prepare a new sponge for controlling bleeding. The extracted fish has high purity, uniform molecular size hydroxyproline content. peptide chain structure high-level are intactly preserved....
Extracellular matrix (ECM) material with good biological activity is essential to simulate cell growth microenvironment, induce infiltration and angiogenesis, promote the repair of large area acute skin wound. In this study, tilapia acellular dermal (TADM) was prepared ECM which can substantial wound healing in rats. The main component TADM type I collagen, has physical chemical properties, adhesion. a form biomaterial low immunogenicity, risk prion infection lower economic cost than other...
Peptides bind MHC class I molecules by anchoring hydrophobic side chains into pockets in the peptide binding groove. Here, we report an immunogenic (in vitro and vivo) MUC1 glycopeptide (MUC1-8-5GalNAc) bound to H-2Kb, fully crossreactive with nonglycosylated variant. Molecular modeling showed that central P5-Thr-GalNAc residue points C pocket forms van der Waals hydrogen bond interactions I. As predicted, GalNAc, a modified carrying additional anchor pocket, increased affinity approximately...
Abstract Our aim was to investigate the effects of phycocyanin (PC) on bleomycin (BLM)-induced pulmonary fibrosis (PF). In this study, C57 BL/6 wild-type (WT) mice and toll-like receptor (TLR) 2 deficient were treated with PC for 28 days following BLM exposure. Serum lung tissues collected 3, 7 28. Data shows significantly decreased levels hydroxyproline (HYP), vimentin, surfactant-associated protein C (SP-C), fibroblast specific protein-1 (S100A4) α-smooth muscle actin (α-SMA) but...
Abstract Background Radiation‐induced gastrointestinal syndrome, including nausea, diarrhea, and dehydration, contributes to morbidity mortality after medical or industrial radiation exposure, which seriously affects patient quality of life treatment. No safe effective countermeasure has been approved for clinical therapy. In this study, we aimed investigate the potential protective effects phycocyanin (PC) against radiation‐induced acute intestinal injury. Materials Methods C57BL/6 mice...
The prevention and treatment of chronic obstructive pulmonary disease (COPD) is closely tied to anti-oxidation anti-inflammation. Phycocyanin (PC) have numerous pharmacological effects such as anti-oxidation, anti-inflammation, so on. But it remains unclear whether PC can play a therapeutic role in COPD. As inflammation oxidative stress aggravate the COPD, this study explore effect on COPD mice its mechanisms. model was established by exposing lipopolysaccharide (LPS) cigarette smoke (CS),...
Abstract BACKGROUND A water‐in‐oil‐in‐water (W/O/W) double emulsion can simultaneously load hydrophilic and hydrophobic substances due to its unique two‐membrane, three‐phase structure. However, thermodynamic instability greatly limits the application of emulsions in food processing. Further development Pickering based on proteins, etc., improve stability loading capacity. It is great significance promote their practical application. RESULTS Herein, we prepared ultrasound pretreatment...
Titania powders in pure brookite form were synthesized by hydrothermal treatment of titanium(IV) salt solutions. Two kinds starting materials, titanium sulfate and tetrachloride, used the reactions. The effects preparation conditions on polymorphous morphology dioxide studied. These included precursor species, pretreatment, pH, reaction temperature. that lead to formation versus other phases, such as anatase rutile, are generalized. morphologic differences three shown.
Objective: Study the repair effect of tilapia collagen on acute wounds, and expression level related genes its metabolic direction in process. Materials methods: After full-thickness skin defect model was constructed standard deviation rats, wound healing observed evaluated by means characterization, histology, immunohistochemistry. RT-PCR, fluorescence tracer, frozen section other techniques were used to observe fish process repair. Results: implantation, there no immune rejection reaction,...