A5102964294- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Retinal Imaging and Analysis
- Esophageal Cancer Research and Treatment
- Corneal surgery and disorders
- Retinal and Optic Conditions
- Liver Disease Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- Lung Cancer Treatments and Mutations
- Esophageal and GI Pathology
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease and Transplantation
- Ocular Surface and Contact Lens
- Gastric Cancer Management and Outcomes
- Ophthalmology and Visual Health Research
- Hepatitis B Virus Studies
- Pancreatic and Hepatic Oncology Research
- Gastroesophageal reflux and treatments
- Hepatitis C virus research
- Helicobacter pylori-related gastroenterology studies
- Nutrition and Health in Aging
- Lung Cancer Diagnosis and Treatment
- Eosinophilic Esophagitis
- Cardiac, Anesthesia and Surgical Outcomes
University of Hong Kong
1997-2024
Cyberport
2021-2024
Chinese University of Hong Kong
2003-2022
Grantham Hospital
2019-2022
Prince of Wales Hospital
2003-2019
Cancer Care Ontario
2019
Caritas Medical Centre
2015
Liverpool Hospital
2013
Royal Prince Alfred Hospital
2009
Queen Mary Hospital
1986-2003
Postoperative hepatic failure is the leading cause of hospital mortality following hepatectomy for hepatocellular carcinoma (HCC). This prospective study was performed to identify best test assessment adequacy functional reserve in patients with HCC before hepatectomy.Between April 1989 and June 1993, 127 underwent hepatectomy. Each patient evaluated operation indocyanine green (ICG) clearance test, aminopyrine breath amino acid test.Fourteen (11 per cent) died after ICG retention at 15 min...
Abstract Background Extended hepatectomy with resection of more than four segments is a high-risk operation, especially in patients hepatocellular carcinoma (HCC) associated chronic liver disease. This study evaluated the risk factors for morbidity and mortality following extended HCC. Methods Preoperative intraoperative variables 155 who underwent HCC were analysed to identify postoperative mortality. Results The overall rate was 55·5 per cent (n = 86). Most due ascites or pleural effusion....
Purpose: We investigate macular perfusion and the systemic ocular associations in a population-based setting. Methods: In this cross-sectional study, 2018 adults residing Hong Kong underwent detailed ophthalmic examinations after consenting to participate. Macular was measured with optical coherence tomography angiography (OCTA) using split-spectrum amplitude decorrelation algorithm. The parafoveal flow index vessel area density were quantified automated custom-built software. Results: Of...
This study compared the results of hepatectomy for hepatocellular carcinoma (HCC) using an ultrasonic dissector with those a combination crushing clamp and finger fracture techniques. The method was used from 1989 to 1992 in 96 patients (group 1) 1993 1994 69 2). Data these two sets were collected prospectively. groups comparable terms preoperative liver function, tumour size stage, incidence cirrhosis. Major performed (72 per cent) group 1 52 (75 2. Use resulted lower mean (s.e.m.) blood...
Abstract Castrostomy feeding has been a well established form of nutritional support for patients presenting with total dysphgia carcinoma the oesophagus. More recently, parenteral nutrition proved to be efficient and safe, offering an alternative gastrostomy feeding. Twenty-four were randomly selected into two groups compare efficacy respect nitrogen balance weight gain. Total was found superior in achieving earlier positive greater gain during 4-week period. However, is still preferred as...
Liver failure is the commonest cause of postoperative death in patients with hepatocellular carcinoma (HCC). With improvement operative technique and perioperative care, limit hepatic functional reserve may be lowered. The aim this study was to evaluate morbidity, mortality survival rates an indocyanine green (ICG) retention value higher than 14 per cent, after major hepatectomy for HCC.From January 1994 December 1997, 117 underwent HCC; 92 had preoperative ICG at 15 min lower cent (median...
Emergency colorectal surgery in the elderly has been associated with a high mortality rate. Although current trend for management of obstructing left-sided carcinoma favours primary resection and anastomosis, safety benefits this approach have not studied.Some 57 (aged more than 70 years) 59 younger patients underwent emergency an acutely carcinoma. Postoperative results two groups were compared.The rate was 95 per cent 89 (P = 0.70), anastomosis 84 78 respectively 0.64). Elderly had...
A total of 277 patients with hepatocellular carcinoma (HCC) underwent hepatic resection over a 20-year period. Twelve 36 recurrence confined to extrahepatic organs surgical resection. There were no complications but one patient died in hospital from secondary intrahepatic recurrence. The 1-, 2- and 5-year survival rates for these 12 after 92, 52 26 per cent respectively better than those 24 who did not undergo mean following recurrent disease was 19.7 months the longest time nearly 8 years....
Abstract Background The intermittent Pringle manoeuvre during hepatectomy results in a better clinical outcome when the accumulated ischaemia time is less than 120 min. aim of this study was to investigate hepatic gene expression related microcirculatory modulation and ultrastructural changes patients having manoeuvre. Methods Forty who underwent for liver tumours were randomly assigned transection with (Pringle group, n = 20) or without (control 20). data endothelin (ET) 1 endothelial...
The relative merits of proximal gastric vagotomy (PGV), truncal with drainage (TV + D), and antrectomy A) in the treatment chronic duodenal ulcer were evaluated compared 152 patients a prospective, randomized controlled clinical trial. One death occurred after TV A, resulting an operative mortality 2% gastrectomy 0.7% for entire series. After one to six years, stomal ulcers proven by endoscopy eight PGV (16%) D (11.8%); difference was not statistically significant (p > 0.5). additional...
We compared the results of 327 transthoracic (TT) resections and 82 transhiatal (TH) for carcinoma oesophagus operated on between July 1982 June 1991. Significantly more patients with lower third (54% versus 28%) increased pulmonary risks surgery (61% 22%) were selected TH approach as TT approach. Results showed comparable intraoperative complications two groups. 5% in group required a thoracotomy control haemorrhage (3 patients) repair bronchial tear (1 patient) which occurred during...
Simple closure, the conventional operation for perforated acute duodenal ulcers, is associated with symptomatic relapse in a large proportion of patients. In order to assess role immediate definitive surgery, 78 fit patients ulcers were prospectively randomized undergo either closure alone or proximal gastric vagotomy (PGV). Patients taking potentially ulcerogenic drugs who had severe stress excluded from study. Both groups comparable respect age, sex, general medical health, duration...
Abstract Data were collected prospectively from 159 patients undergoing Lewis-Tanner oesophagectomy for carcinoma of the lower two-thirds oesophagus and analysed with regard to anastomotic leakage. The 30-day mortality rate was 3·8 per cent none these deaths due In hospital, 7·5 cent. Six (3·8 percent) had evidence a leak. four this suture line, but in remaining two it patches gangrene fundus transposed stomach separate anastomosis. Two died an unhealed Anastomotic leaks minor three...
Abstract Hypersecretion of gastric acid and hypergastrinaemia occur when the antrum stomach is transposed as a diverticulum to colon. Thus, an antral pouch increase bladder capacity or replace gastrocystoplasty, similar pathophysiological disturbances can be anticipated. However, previous studies in our laboratories dogs have shown that overproduction stomal ulcerations do not occur. This paper reports results gastrocystoplasty 13 patients followed up from 1 6 years. Gastric hypersecretion did
Purpose To investigate the prevalence, associations, and causes of visual impairment blindness in adult population Hong Kong.Methods This cross-sectional population-based study included 2018 (870, 43% male) randomly selected adults with a mean age 52 ± 16 years (range 18–90 years) Kong. Each participant underwent comprehensive ophthalmic examinations. Presenting acuity (PVA) best-corrected (BCVA) each eye was recorded. Prevalence calculated using both World Health Organization (WHO) United...
KEYWORDS: Biomimeticcornea-on-a-chipeye-on-a-chipmicroengineeredmicrofluidicsophthalmic drugocular modelorgan-on-a-chipretina-on-a-chip
Clonorchiasis may lead to cholangitis. Clonorchis sinensis infiltration of the biliary system produces an easily recognisable cholangiographic picture. The findings consist characteristic filling defects and changes in intrahepatic extrahepatic ducts. are usually small irregular size is uniform. change ducts consists ductal dilatation involving especially smaller ducts, apparent elongation, tortuosity duct wall irregularities. mainly irregularities a mild degree dilatation. recognition...