A5102740831- Muscle Physiology and Disorders
- Phytoestrogen effects and research
- Phytochemical compounds biological activities
- Adipose Tissue and Metabolism
- Sirtuins and Resveratrol in Medicine
- Plant Ecology and Taxonomy Studies
- Mitochondrial Function and Pathology
- Plant-derived Lignans Synthesis and Bioactivity
- Thyroid Disorders and Treatments
- Sesquiterpenes and Asteraceae Studies
- Natural product bioactivities and synthesis
- Medicinal plant effects and applications
- Plant Pathogens and Resistance
- Mycotoxins in Agriculture and Food
- Exercise and Physiological Responses
- Insect and Pesticide Research
- Cardiac Ischemia and Reperfusion
- Ubiquitin and proteasome pathways
- Bone health and treatments
- Moringa oleifera research and applications
- Bioactive natural compounds
- GABA and Rice Research
- Dermatology and Skin Diseases
- Public Administration in Developing Nations
- Synthesis of Organic Compounds
Osaka University of Pharmaceutical Sciences
2025
Kano State University of Technology
2024
The Radiosurgery Society
2023
Mukogawa Women's University
1994-2016
Tokushima University
2013-2016
Umaru Musa Yar'adua University
2016
Kyoto Pharmaceutical University
1995-2014
Meijo University
1993
Proinflammatory cytokines are factors that induce ubiquitin-proteasome-dependent proteolysis in skeletal muscle, causing muscle atrophy. Although isoflavones, as potent antioxidative nutrients, have been known to reduce damage during the catabolic state, non-antioxidant effects of isoflavones against atrophy not well known. Here we report on inhibitory such genistein and daidzein caused by tumor necrosis factor (TNF)-α treatment. In C2C12 myotubes, TNF-α treatment markedly elevated...
Public service innovation has become a strategic approach to improving the quality of public services in many places Indonesia. This study analyzes development Service Mall (PSM) Barru Regency as an integrated model that aims improve efficiency, accessibility, and community satisfaction. Using qualitative explanatory case approach, data was collected through in-depth interviews, direct observation, analysis official documents. The results showed PSM increased speed convenience by decreasing...
Several derivatives of podophyllotoxin with modifications at the C-4 position ring C, in addition to demethylation C-4' E, were examined for inhibitory activity against DNA topoisomerase II and tubulin polymerization, generation protein-linked breaks, cytotoxicity KB cells VP-16-resistant variants. Substitution a group beta configuration C resulted compounds greater lower polymerization than those an alpha configuration. These active analogs exhibited same mechanism inhibition as...
Proinflammatory cytokines contribute to the progression of muscle wasting caused by ubiquitin-proteasome-dependent proteolysis. We have previously demonstrated that isoflavones, such as genistein and daidzein, prevent TNF-α-induced atrophy in C2C12 myotubes. In this study, we examined effect dietary flavonoids on muscle. Mice were divided into following four groups: vehicle-injected (control) mice fed normal diet (CN); tumor-bearing (TN); control isoflavone (CI); (TI). There no significant...
Uncoupling protein 3 (UCP3) and pyruvate dehydrogenase kinase 4 (PDK4) in skeletal muscle are key regulators of the glucose lipid metabolic processes that involved insulin resistance. Medium-chain fatty acids (MCFAs) have anti-obesogenic effects rodents humans, while long-chain (LCFAs) cause increases body weight To clarify beneficial MCFAs, we examined UCP3 PDK4 expression muscles mice fed a MCFA- or LCFA-enriched high-fat diet (HFD). Five-week feeding HFD caused high gain induced...
It was verified, by n.m.r. and fast‐atom‐bombardment‐m.s. studies, that the C‐2 position of 1,5‐anhydro‐D‐fructose, which prepared reaction immobilized glucose 2‐oxidase from Coriolus versicolor (with 1,5‐anhydro‐D‐glucitol), is hydrated to acetal form in water. The effects 1,5‐anhydro‐D‐fructose on several glucose‐metabolizing enzymes were compared with those 1,5‐anhydro‐D‐glucitol. Glucose 1‐oxidase Aspergillus niger inhibited (Ki 6.6 mM) more effectively than 1,5‐anhydro‐D‐glucitol 82.5...
Spices and condiments get contaminated with fungi aflatoxin due to poor agricultural storage practices. A total of 42 dried, raw, powdered processed samples representing fourteen different types spices were randomly collected in new polythene bags from Katsina central market (Katsina town) screened for contaminations. These Clove, African nutmeg, Ashanti pepper, Candlewood, Ethiopian Pineapple the bush, Ginger, Garlic, Chillies, Kajiji, Thyme, Chilli powder (yaji), Curry Locust bean...
The need to improve quality of aquafeed that would bring about higher aquaculture yield hasattracted attention for the inclusion Plant materials into fish feed. This study investigatedthe Moringa oleifera and Eucalyptus globulus leaf extracts diets Clarias gariepinus fingerings. A feeding trials 56 -days duration was involved in this study. trial made eight isonitrogenous 40%CP comprising sixexp erimental diets, a control diet (ZSD) reference commercial (CRD). Three six had each with 2%...
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Abstract Durch Reduktion von Aristolochinsäure (I) mit NaBH 4 in Diglyme bei Raumtemperatur entsteht 80‐85%iger Ausbeute 9,10‐Dihydroaristolochinsäure (II) neben einer geringen Menge 3,4‐Methylendioxy‐8‐methoxyphenanthren‐1‐carbonsäure (III), die als einziges Hydrierungsprodukt 75‐80%iger erhalten wird, wenn man 90‐100°C durchführt.