A5085704257- Vector-borne infectious diseases
- Viral Infections and Vectors
- Vector-Borne Animal Diseases
- Dermatological diseases and infestations
- Mosquito-borne diseases and control
- Autoimmune Neurological Disorders and Treatments
- Yersinia bacterium, plague, ectoparasites research
- Parasites and Host Interactions
- Herpesvirus Infections and Treatments
- CRISPR and Genetic Engineering
- Clinical Nutrition and Gastroenterology
- Chronic Lymphocytic Leukemia Research
- Pediatric Hepatobiliary Diseases and Treatments
- Immunodeficiency and Autoimmune Disorders
- Bartonella species infections research
- Gastroesophageal reflux and treatments
- Hereditary Neurological Disorders
- Viral Infections and Immunology Research
- Neurological and metabolic disorders
- Blood groups and transfusion
- Bacterial Infections and Vaccines
- Bacillus and Francisella bacterial research
- Cardiovascular Effects of Exercise
Stavanger University Hospital
2008-2022
University of Bergen
2006
Acute facial nerve palsy in children may be caused by infection Borrelia burgdorferi, but the incidence of and proportion Lyme borreliosis vary considerably between areas. Furthermore, it is not well known how often associated with meningitis. In this population-based study, admitted for acute to Stavanger University Hospital during 9 y from 1996 2004 were investigated a standard protocol including lumbar puncture. A total 115 included, giving an annual 21 per 100,000 children. 75 (65%)...
Neuroborreliosis may be caused by different species of Borrelia burgdorferi (BB) and the clinical presentation neuroborreliosis in children differ between geographical areas due to occurrence BB genospecies. The aim this study was evaluate characteristics with an endemic area Scandinavia. During 1996-2006, suspected referred Stavanger University Hospital were investigated a standard procedure including lumbar puncture. A total 143 diagnosed neuroborreliosis, all cases from April December....
The occurrence of IgM and IgG antibodies against Borrelia burgdoferi in serum cerebrospinal fluid (CSF) intrathecal synthesis (antibody index) were studied relation to clinical presentation the duration symptoms before diagnosis 146 children diagnosed with neuroborreliosis. Lymphocytic meningitis was demonstrated 141 these children. Levels white blood cells (WBC) protein CSF correlated significantly numbers d symptoms. Children divided into 3 groups: A (n = 37): only cranial neuropathy; B...
<h3>Objective</h3> To evaluate the epidemiology of infectious meningitis in children a Lyme borreliosis (LB) endemic area, and to study how clinical laboratory characteristics may distinguish between different types childhood meningitis. <h3>Design</h3> Retrospective, population based study. <h3>Setting</h3> A paediatric department serving all (62 000) costal LB region southwestern Norway. <h3>Patients</h3> All with cerebrospinal fluid pleocytosis aged 3 months 14 years. <h3>Main outcome...
The current diagnostic marker of Lyme neuroborreliosis (LNB), the Borrelia burgdorferisensu lato antibody index (AI) in cerebrospinal fluid (CSF), has insufficient sensitivity early phase LNB. We aimed to elucidate value PCR for B. CSF from children with symptoms suggestive LNB and explore genotypes associated children. Children were prospectively included predefined groups a high or low likelihood based on guidelines (LNB symptoms, pleocytosis, antibodies) detection other causative agents....
Current markers of Lyme neuroborreliosis (LNB) in children have insufficient sensitivity the early stage disease. The B-lymphocyte chemoattractant CXCL13 cerebrospinal fluid (CSF) may be useful diagnosing LNB, but its specificity has not been evaluated studies including with clinically relevant differential diagnoses. aim this study was to elucidate diagnostic value CSF symptoms suggestive LNB.Children LNB were included prospectively into predefined groups a high or low likelihood based on...
Background . Many neurological diseases show differences between genders. We studied gender in childhood Lyme neuroborreliosis (LNB) an endemic area of borreliosis Norway. Methods In a population based study, all children (<14 years age) with symptoms suspicious LNB, including acute facial nerve palsy, were evaluated for LNB by medical history, clinical examination, blood tests, and lumbar puncture. was diagnosed according to international criteria. Results 142 during 2001–2009. Facial...
Background: The B-lymphocyte chemokine CXCL13 is increasingly considered as a useful early phase diagnostic marker of Lyme neuroborreliosis (LNB). However, the large variation in level cerebrospinal fluid (CSF) observed LNB patients still unexplained. We aimed to identify factors associated with children LNB, possibly improving interpretation LNB. Methods: Children confirmed and probable were included prospective study on CSF variables age, sex, facial nerve palsy, generalized inflammation...
A bile acid homeostasis disorder was suspected in 2 siblings and their second cousin who presented infancy with fat malabsorption, severe fat-soluble vitamin deficiency, rickets, mild liver involvement. Our aims were to identify the genetic cause, describe disease, evaluate response ursodeoxycholic (UDCA) treatment.Whole exome sequencing, immunohistochemistry of duodenal biopsies candidate variant testing a cell-based model performed. Fecal excretion, serum acids,...
23.04.2013: Brev til redaktøren - Då dette sjukdomstilfellet på mange måtar er spesielt, både epidemiologisk (det første i Østfold) og klinisk (minner meir om Guillain-Barrés syndrom enn skogflåttencefalitt), synest vi at diagnosen burde vore betre underbygd serologisk.