A5010308992- Metabolism and Genetic Disorders
- Neonatal Health and Biochemistry
- Genomics and Rare Diseases
- Brucella: diagnosis, epidemiology, treatment
- Escherichia coli research studies
- Biochemical and Molecular Research
- Mitochondrial Function and Pathology
- Methemoglobinemia and Tumor Lysis Syndrome
- Bacteriophages and microbial interactions
- Monoclonal and Polyclonal Antibodies Research
- Folate and B Vitamins Research
- Child and Adolescent Health
- Autopsy Techniques and Outcomes
- Biochemical and Structural Characterization
- Ear Surgery and Otitis Media
- Enterobacteriaceae and Cronobacter Research
- Mycobacterium research and diagnosis
- Hemoglobinopathies and Related Disorders
- Viral gastroenteritis research and epidemiology
- Amino Acid Enzymes and Metabolism
- Pediatric health and respiratory diseases
- Diet and metabolism studies
- Genetics and Neurodevelopmental Disorders
- Streptococcal Infections and Treatments
- Salmonella and Campylobacter epidemiology
Saint Joseph University
2006-2024
American University of Beirut
2001-2002
American University of Beirut New York Office
1996
We developed a PCR-based assay for the rapid and specific laboratory diagnosis of human brucellosis directly from whole blood. Specimens were collected in EDTA tubes 17 patients with acute serologic 3 chronic relapsing as determined by tests patient's clinical picture. DNA was extracted peripheral mononuclear cells obtained blood control individuals. Specific primers PCR amplification 223-bp region on sequence encoding 31-kDa immunogenic Brucella abortus protein (BCSP 31) used. All amplicons...
Objectives Few countries in the Middle East-North Africa region have adopted national newborn screening for inborn errors of metabolism by tandem mass spectrometry (MS/MS). We aimed to evaluate cost-benefit such disorders Lebanon, as a model other developing region. Methods Average costs expected care cases group, between ages 0 and 18, early late diagnosed, were calculated from 2007 2013. The monetary value detection using MS/MS was compared with that clinical “late detection”, including...
This special edition of the International Journal Neonatal Screening includes presentations fourth Meeting Middle East North Africa (MENA) Region Society for (ISNS) held in Limassol, Cyprus, March 8–11, 2020 [...]
Because of lack worldwide standardization influenza virus surveillance, comparison between countries impact a pandemic is challenging. For that, other approaches to allow internationally comparative serosurveys are welcome.Here we explore the use neonatal screening dried blood spots monitor trends 2009 A (H1N1) pdm by protein microarray.We contacted colleagues from laboratories and asked for their willingness participate in study testing anonymized bloodspots collected during course...
Citrullinemia type 1 (CTLN1) is a rare autosomal recessive disease caused by argininosuccinate synthetase (ASS) deficiency. Manifestations vary from the acute neonatal or "classic" form to milder, late-onset, "unconventional" form. To date, more than 93 variants in ASS1 gene located on chromosome 9q43.11 (OMIM #215700) are reportedly responsible for CTLN1. Their incidence and distribution according geographic origins ethnicity, correlation, although not clearly delineated, has been...
In several hospitals in Beirut, Lebanon, 77 isolates of Escherichia coli were successfully derived from the stools patients with diarrhoeal diseases, by culture on MacConkey or MacConkey-sorbitol agar. When screened, using a multiplex PCR, 14 (from different patients) each found positive for one various genes defining enterotoxigenic (five), enteroinvasive (four), enteroaggregative (three) enteropathogenic (two) groups. Genotyping these diarrhoeagenic isolates, pulsed-field gel...
The incidence of glucose-6-phosphate dehydrogenase (G6PD) deficiency in Lebanon is estimated at 10 per 1000 men and 0.4 women. A community-based cluster sampling survey was conducted 15 villages all areas Lebanon. found 36 cases G6PD among 3000 aged 14 years above, yielding a cumulative rate 12 1000. Of those cases, 28 (77.8%) knew their problem since they had already suffered least one severe anaemia crisis childhood following the ingestion raw green fava beans. remaining 22.2% were not...