Manuel Oliveira

ORCID: 0000-0003-4104-4416
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About
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Research Areas
  • Fatty Acid Research and Health
  • Pediatric Hepatobiliary Diseases and Treatments
  • Infant Nutrition and Health
  • Breast Cancer Treatment Studies
  • Hernia repair and management
  • Pancreatic and Hepatic Oncology Research
  • Health, Nursing, Elderly Care
  • Congenital Diaphragmatic Hernia Studies
  • Gastrointestinal disorders and treatments
  • Thyroid Cancer Diagnosis and Treatment
  • Neuroendocrine Tumor Research Advances
  • Neuroblastoma Research and Treatments
  • Foreign Body Medical Cases
  • Cardiac Arrhythmias and Treatments
  • Diet and metabolism studies
  • Pancreatitis Pathology and Treatment
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Breast Implant and Reconstruction
  • Child Nutrition and Feeding Issues
  • Comparative Animal Anatomy Studies
  • Digital Imaging in Medicine
  • Eicosanoids and Hypertension Pharmacology
  • Cardiac Imaging and Diagnostics
  • Vascular anomalies and interventions
  • Diet, Metabolism, and Disease

Centro Hospitalar de Vila Nova de Gaia
2008-2025

Universidade de Brasília
2024

Nestlé (Switzerland)
2007-2023

Hospital de São João
1988-2022

Hospital Padre Américo
2020

Nestlé (France)
2019

Hospital Universitari Arnau de Vilanova
2016

Hospital Clínico Universitario de Valencia
2016

Universidade Paulista
2015

Fernando Pessoa University
2010-2013

Abstract Sphingomyelin (SM) supports brain myelination, a process closely associated with cognitive maturation. The presence of SM in breast milk suggests role infant nutrition; however, little is known about contribution to healthy development. We investigated the link between early life dietary SM, later development and myelination using an exploratory observational study neurotypical children. levels were quantified nutrition products fed first three months myelin content (brain MRI) as...

10.1523/eneuro.0421-18.2019 article EN cc-by-nc-sa eNeuro 2019-07-01

Catechin is a flavonoid present in fruits, wine and cocoa products. Most foods contain the (+)-enantiomer of catechin but chocolate mainly contains ( - )-catechin, addition to its major flavanol, )-epicatechin. Previous studies have shown poor bioavailability when consumed chocolate. We compared absorption ) (+)-catechin after situ perfusion 10, 30 or 50 micromol/l each enantiomer jejunum ileum rat. also assayed 23 samples for (+) )-catechin. Samples were analyzed using HPLC with Cyclobond...

10.1080/10715760600868545 article EN Free Radical Research 2006-01-01

Phospholipids (PL) or partial acylglycerols such as sn-1(3)-monoacylglycerol (MAG) are potent dietary carriers of long-chain polyunsaturated fatty acids (LC-PUFA) and have been reported to provide superior bioavailability when compared conventional triacylglycerol (TAG). The main objective the present study was compare incorporation docosahexaenoic acid (DHA) in plasma, erythrocytes, retina brain tissues adult rats provided PL (PL-DHA) MAG (MAG-DHA). Conventional DHA oil containing TAG...

10.3390/nu10050620 article EN Nutrients 2018-05-15

To investigate the immunohistochemical and molecular genetic features of cadherins/catenins complex in thyroid carcinoma based on hypothesis that poorly differentiated represents an intermediate step between well-differentiated undifferentiated carcinomas.Immunohistochemistry for E-, P- N-cadherins alpha-, beta- gamma-catenins was performed a series 17 cases thyroid. All showed absence membranous expression E-cadherin with no aberrant or N-cadherins; regarding catenins there heterogeneous...

10.1046/j.1365-2559.2003.01642.x article EN Histopathology 2003-05-23

The aim of this study was to evaluate the factors that determine esthetic outcome after breast cancer conservative treatment, based on a consensual classification obtained with an international consensus panel. Photographs were taken from 120 women submitted unilateral surgery (with or without axillary surgery) and radiotherapy. images sent panel observers 13 different countries result (recorded as excellent, good, fair poor) in 113 cases by means Delphi method. For each patient, data...

10.1111/j.1524-4741.2007.00394.x article EN The Breast Journal 2007-02-20

O Núcleo de Inovação Tecnológica (NIT) foi concebido como o agente da implantação das inovações e resolução problemas colaborativamente entre universidades empresas. Na sua grande maioria, os casos êxito na transferência inovação, estão vinculados a cinco características: primeira diz respeito ao poder administração, que em maiores proporções compreende capacidade efetuar decisões forma mais pronta satisfazendo as suas exigências; treinamento constante seus funcionários torna inserção no...

10.55905/rdelosv18.n64-083 article PT cc-by-nc DELOS Desarrollo Local Sostenible 2025-02-14

Este texto tem como objetivo pontuar e refletir teoricamente sobre o desenvolvimento das atividades de Extensão Universitária desenvolvidas em distintas regiões centros saber, localizados no Norte Sul do Brasil. A ideia é apresentar experiências diversas, considerando ponto comum a atividade da Universitária, compreendida metaforicamente trilhas, rotas incertas efêmeras constituídas por pegadas, que são marcas quem somos, encontramos nos transformamos processo fazer extensão. Identificamos...

10.21680/2238-6009.2024v1n63id35792 article PT cc-by-nc-sa Vivência Revista de Antropologia 2025-03-19

Abstract Introduction Pacemaker patients have a high risk of developing HFpEF due to age, long-term cardiac changes secondary artificial pacing, and associated comorbidities. Despite this risk, remains underdiagnosed poorly characterized in population. Purpose Perform systematic screening for heart failure with preserved ejection fraction (HFpEF) pacemaker assess prevalence characterize Methods We conducted large cross-sectional study screen all right ventricular apical implanted between...

10.1093/europace/euaf085.565 article EN cc-by-nc EP Europace 2025-05-01

In the present study, we used a preclinical model of induced lipolytic enzyme insufficiency, and hypothesized that use monoacylglycerols (MAG) will enhance their bioavailability delivery to tissues. Experimental diets containing 20% lipids were fed rats for 21 days with or without Orlistat. The control diet fish oil (FO), source EPA DHA, was tested against: structured (A) vanillin acetal sn-2 MAG (Vanil + O) (B) diacetyl derivative (Acetyl (C) free (MAG O). FA profiles an emphasis on DHA...

10.3390/nu4111781 article EN Nutrients 2012-11-21

Compared with wild-type (WT) mice, biglycan/fibromodulin double-deficient mice develop severe knee osteoarthritis. We undertook this study to compare type II collagen catabolism in the 2 genotypes and usefulness of 3 biomarkers degradation (C2C [also known as Col2-3/4C(long mono)] well peptide Coll2-1 its nitrated form, Coll2-1NO2) for evaluating vivo.In 15 WT we determined serum levels C2C at ages 66 141 days, Coll2-1NO2 49, 81, 95, days. Expression sections was examined using...

10.1002/art.22875 article EN Arthritis & Rheumatism 2007-09-28

Abstract Background Inflammatory bowel diseases (IBD) are chronic intestinal inflammatory affecting about 1% of western populations. New eating behaviors might contribute to the global emergence IBD. Although immunoregulatory effects omega-3 fatty acids have been well characterized in vitro, their role IBD is controversial. Methods The aim this study was assess impact increased fish oil intake on colonic gene expression, eicosanoid metabolism and development colitis a mouse model Rag-2...

10.1186/1476-511x-12-81 article EN cc-by Lipids in Health and Disease 2013-05-31
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