- Fatty Acid Research and Health
- Pediatric Hepatobiliary Diseases and Treatments
- Infant Nutrition and Health
- Breast Cancer Treatment Studies
- Hernia repair and management
- Pancreatic and Hepatic Oncology Research
- Health, Nursing, Elderly Care
- Congenital Diaphragmatic Hernia Studies
- Gastrointestinal disorders and treatments
- Thyroid Cancer Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Neuroblastoma Research and Treatments
- Foreign Body Medical Cases
- Cardiac Arrhythmias and Treatments
- Diet and metabolism studies
- Pancreatitis Pathology and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Breast Implant and Reconstruction
- Child Nutrition and Feeding Issues
- Comparative Animal Anatomy Studies
- Digital Imaging in Medicine
- Eicosanoids and Hypertension Pharmacology
- Cardiac Imaging and Diagnostics
- Vascular anomalies and interventions
- Diet, Metabolism, and Disease
Centro Hospitalar de Vila Nova de Gaia
2008-2025
Universidade de Brasília
2024
Nestlé (Switzerland)
2007-2023
Hospital de São João
1988-2022
Hospital Padre Américo
2020
Nestlé (France)
2019
Hospital Universitari Arnau de Vilanova
2016
Hospital Clínico Universitario de Valencia
2016
Universidade Paulista
2015
Fernando Pessoa University
2010-2013
Abstract Sphingomyelin (SM) supports brain myelination, a process closely associated with cognitive maturation. The presence of SM in breast milk suggests role infant nutrition; however, little is known about contribution to healthy development. We investigated the link between early life dietary SM, later development and myelination using an exploratory observational study neurotypical children. levels were quantified nutrition products fed first three months myelin content (brain MRI) as...
Catechin is a flavonoid present in fruits, wine and cocoa products. Most foods contain the (+)-enantiomer of catechin but chocolate mainly contains ( - )-catechin, addition to its major flavanol, )-epicatechin. Previous studies have shown poor bioavailability when consumed chocolate. We compared absorption ) (+)-catechin after situ perfusion 10, 30 or 50 micromol/l each enantiomer jejunum ileum rat. also assayed 23 samples for (+) )-catechin. Samples were analyzed using HPLC with Cyclobond...
Phospholipids (PL) or partial acylglycerols such as sn-1(3)-monoacylglycerol (MAG) are potent dietary carriers of long-chain polyunsaturated fatty acids (LC-PUFA) and have been reported to provide superior bioavailability when compared conventional triacylglycerol (TAG). The main objective the present study was compare incorporation docosahexaenoic acid (DHA) in plasma, erythrocytes, retina brain tissues adult rats provided PL (PL-DHA) MAG (MAG-DHA). Conventional DHA oil containing TAG...
To investigate the immunohistochemical and molecular genetic features of cadherins/catenins complex in thyroid carcinoma based on hypothesis that poorly differentiated represents an intermediate step between well-differentiated undifferentiated carcinomas.Immunohistochemistry for E-, P- N-cadherins alpha-, beta- gamma-catenins was performed a series 17 cases thyroid. All showed absence membranous expression E-cadherin with no aberrant or N-cadherins; regarding catenins there heterogeneous...
The aim of this study was to evaluate the factors that determine esthetic outcome after breast cancer conservative treatment, based on a consensual classification obtained with an international consensus panel. Photographs were taken from 120 women submitted unilateral surgery (with or without axillary surgery) and radiotherapy. images sent panel observers 13 different countries result (recorded as excellent, good, fair poor) in 113 cases by means Delphi method. For each patient, data...
O Núcleo de Inovação Tecnológica (NIT) foi concebido como o agente da implantação das inovações e resolução problemas colaborativamente entre universidades empresas. Na sua grande maioria, os casos êxito na transferência inovação, estão vinculados a cinco características: primeira diz respeito ao poder administração, que em maiores proporções compreende capacidade efetuar decisões forma mais pronta satisfazendo as suas exigências; treinamento constante seus funcionários torna inserção no...
Este texto tem como objetivo pontuar e refletir teoricamente sobre o desenvolvimento das atividades de Extensão Universitária desenvolvidas em distintas regiões centros saber, localizados no Norte Sul do Brasil. A ideia é apresentar experiências diversas, considerando ponto comum a atividade da Universitária, compreendida metaforicamente trilhas, rotas incertas efêmeras constituídas por pegadas, que são marcas quem somos, encontramos nos transformamos processo fazer extensão. Identificamos...
Abstract Introduction Pacemaker patients have a high risk of developing HFpEF due to age, long-term cardiac changes secondary artificial pacing, and associated comorbidities. Despite this risk, remains underdiagnosed poorly characterized in population. Purpose Perform systematic screening for heart failure with preserved ejection fraction (HFpEF) pacemaker assess prevalence characterize Methods We conducted large cross-sectional study screen all right ventricular apical implanted between...
In the present study, we used a preclinical model of induced lipolytic enzyme insufficiency, and hypothesized that use monoacylglycerols (MAG) will enhance their bioavailability delivery to tissues. Experimental diets containing 20% lipids were fed rats for 21 days with or without Orlistat. The control diet fish oil (FO), source EPA DHA, was tested against: structured (A) vanillin acetal sn-2 MAG (Vanil + O) (B) diacetyl derivative (Acetyl (C) free (MAG O). FA profiles an emphasis on DHA...
Compared with wild-type (WT) mice, biglycan/fibromodulin double-deficient mice develop severe knee osteoarthritis. We undertook this study to compare type II collagen catabolism in the 2 genotypes and usefulness of 3 biomarkers degradation (C2C [also known as Col2-3/4C(long mono)] well peptide Coll2-1 its nitrated form, Coll2-1NO2) for evaluating vivo.In 15 WT we determined serum levels C2C at ages 66 141 days, Coll2-1NO2 49, 81, 95, days. Expression sections was examined using...
Abstract Background Inflammatory bowel diseases (IBD) are chronic intestinal inflammatory affecting about 1% of western populations. New eating behaviors might contribute to the global emergence IBD. Although immunoregulatory effects omega-3 fatty acids have been well characterized in vitro, their role IBD is controversial. Methods The aim this study was assess impact increased fish oil intake on colonic gene expression, eicosanoid metabolism and development colitis a mouse model Rag-2...