Abstract Background Sand flies are responsible for the transmission of several disease pathogens including Leishmania . breed in habitats with high levels humidity and organic matter. They nocturnal nature peak activity ranges from dusk to dawn. The scientific evidence on breeding ecology diurnal resting sites sand fly fauna important aspects planning implementing vector control activities. However, such fundamental information is grossly inadequate Sri Lanka support efforts country....

Cutaneous leishmaniasis (CL) is a neglected tropical disease which affects mainly the poorest communities in developing countries. Considering limited published information on economic impact of CL Sri Lanka, current study was conducted with objective revealing nature and magnitude three selected endemic regions Kurunegala District, Lanka. The patient records notified relevant Medical Officer Health (MOH) office during 2013- 2016 were obtained. Patient households visited data collection done...

Abstract Background Leishmaniasis is a neglected tropical disease that affects countries in the developing world. In Sri Lanka, cutaneous leishmaniasis most common form of disease. It prevalent dry and intermediate zones, mostly associated with rural settings. Understanding basic risk factors critical management effective interventions. This study focused on assessing demographic, socioeconomic landscape Kurunegala District, Lanka. Methods A descriptive cross-sectional was conducted....

Abstract Background Phlebotomine sand flies are a medically important group of insects that is responsible for the transmission leishmaniasis. Surveillance plays major role in vector control programmes through exploring species abundance, potential entomological risk and designing appropriate measures. In field surveillance such nature, morphological identification paramount importance. However, Sri Lanka, there no published taxonomic key available leishmaniasis vectors. Method...

Phlebotomus argentipes is the main suspected vector for leishmaniasis in Sri Lanka. Investigations on presence of aerobic bacteria gut sand flies which evidence a potential approach to control transmission through paratransgenic strategy are still not available local fly populations. Field-caught unfed female collected from three selected Medical Officer Health (MOH) areas (Polpithigama, Maho, and Galgamuwa) Kurunegala District, Lanka August December 2018 were used. Prokaryotic 16S ribosomal...

The aim was to investigate an emerging focus of cutaneous leishmaniasis (CL) in Gampaha district, Western Sri Lanka.Sociodemographics CL patients Mirigama, were compared with controls using a structured questionnaire. Clinical data and geographic positioning system coordinates recorded. Sandflies collections performed four selected sites indoor hand collection (162 units) cattle-baited net traps (n=3).Of 73 (mean age 43.6 y; SD 20), 58.9% males. Lesions consisted nodules (52.1%) ulcers...

The field-based studies on sand flies are not adequate to uncover information required for the control of leishmaniasis through reduction vector populations. Therefore, establishment and maintenance laboratory colonies is an essential step in research. In current study, a colony P. argentipes was established from wild-caught following standard procedures published literature. Morphological measurements laboratory-reared individual were compared assess difference between two groups....

Strongyloidiasis is caused by the nematode Strongyloides stercoralis which has unique ability to reproduce and complete its entire life cycle within human host through autoinfection cycle. Diagnosis of this infection important because potential cause fatal hyperinfection syndrome or disseminated infections in those with defective cellular immunity. Parasitological methods based on faecal microscopy culture often fail detect low-intensity infections. A multiplex polymerase chain reaction...

Leishmaniasis is a parasitic infection transmitted through the bite of female phlebotomine sand flies. Microscopy gold standard to detect parasites within flies and for vector incrimination. However, molecular-based detection has become more popular nowadays in identification Leishmania since it provides species simultaneously with no need laborious procedures. The entomological surveys were conducted monthly from May October 2017 using techniques. Field-caught identified level followed by...

We compare web properties and fitness of the Giant wood spider Nephila pilpes within outside its natural rainforest habitat in Sri Lanka. The nonforest habitats comprised rural home gardens plantations. hypothesize that marked differences would be evident between two (i) (ii) female spiders. Web architectural silk thread were measured 25 webs adult spiders each habitats, while abdomen size was used as proxy for fitness. Findings support both hypotheses. more closely knit (smaller mesh...

Biting midges, belonging to the Ceratopogonidae family, are a group of dipteran insects implicated as vectors for various parasites and viruses. In Sri Lanka, where leishmaniasis is endemic, biting midges found in high densities, causing significant nuisance. This observation raises possibility that these may serve potential areas. To investigate presence Leishmania donovani within midge populations leishmaniasis-endemic area study was conducted Medawachchiya Medical Officer Health area,...

Invertebrates have evolved to produce peptide compounds ensure success in prey capture and defence against potential enemies. Some of these become highly potent therapeutic used medicine. Melittin, a extracted from bee venom, has emerged as promising option that the obviate disadvantages existing therapeutics several communicable non-communicable diseases. This article reviews peer-reviewed journal articles provide conspectus current research on uses melittin. Melittin is predominantly an...

Abstract Background: Cutaneous leishmaniasis (CL) appears to be spreading previously non-endemic regions of Sri Lanka. The aim this study was describe a newly emerging focus CL in the district Gampaha, Western Methods: A case based descriptive carried out from January 2018 April 2019 Mirigama Medical Officer Health (MOH) area, which reported highest number cases Gampaha District. Laboratory confirmed were traced and socio-demographic clinical data collected via validated questionnaire clinic...

Abstract Background Cutaneous leishmaniasis (CL) appears to be spreading previously non-endemic regions of Sri Lanka. The aim this study was describe a newly emerging focus CL in the district Gampaha, Western Methods A case based descriptive carried out from January 2018 April 2019 Mirigama Medical Officer Health (MOH) area, which reported highest number cases Gampaha District. Laboratory confirmed were traced and socio-demographic clinical data collected via validated questionnaire clinic...