Amy Basilious

ORCID: 0000-0003-4122-5321
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About
Contact & Profiles
Research Areas
  • Retinal and Optic Conditions
  • Retinal Diseases and Treatments
  • Retinal Imaging and Analysis
  • Ophthalmology and Visual Impairment Studies
  • Glaucoma and retinal disorders
  • Cancer Mechanisms and Therapy
  • Ocular Surface and Contact Lens
  • Allergic Rhinitis and Sensitization
  • Ophthalmology and Visual Health Research
  • CRISPR and Genetic Engineering
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Education and Critical Thinking Development
  • Ocular Diseases and Behçet’s Syndrome
  • Congenital Ear and Nasal Anomalies
  • Fibroblast Growth Factor Research
  • Ubiquitin and proteasome pathways
  • Clinical Reasoning and Diagnostic Skills
  • Artificial Intelligence in Healthcare
  • Urticaria and Related Conditions
  • Brain Metastases and Treatment
  • Retinopathy of Prematurity Studies
  • Retinal Development and Disorders
  • Emotional Intelligence and Performance
  • Dermatology and Skin Diseases
  • Retinal and Macular Surgery

St Joseph's Health Care
2022-2025

Western University
2021-2025

St. Joseph's Hospital
2025

University of Windsor
2018-2024

Western University of Health Sciences
2022-2023

Deleted Institution
2023

Abstract Hepatocellular carcinoma (HCC) is one of the leading causes cancer-related deaths worldwide. A variety factors can contribute to onset this disease, including viral infection, obesity, alcohol abuse and non-alcoholic fatty liver disease (NAFLD). These stressors predominantly introduce chronic inflammation cirrhosis finally HCC; however, approximately 20% HCC cases arise in absence via a poorly defined mechanism. The atypical cyclin-like protein Spy1 capable overriding cell cycle...

10.1093/carcin/bgz164 article EN Carcinogenesis 2019-10-01

Abstract Triple negative breast cancer is an aggressive subtype of that relies on systemic chemotherapy as its primary means treatment. Cell cycle regulators are enriched in drug resistant forms the disease supporting potential targeting cell checkpoints a therapeutic direction to re-sensitize patients Spy1 atypical cyclin-like protein can override and elevated triple cancer. We report for first time effects CRISPR-Cas9 mediated knockout functional characteristics cells perform unbiased...

10.1101/2024.03.11.584461 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-03-13

In this narrative, the author describes how she hears story of someone who is victim abuse, but could not have known about vicitm's abuse and many fears. These fears include fear others' judgment, screams, abandonment, being with others. these stories, has heard unspoken burdens others around her. This particular taught compassion, empathy, patience when interacts her patients, colleagues, friends. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

10.1037/fsh0000869 article EN Families Systems & Health 2024-09-01

The current diagnostic aids for acute vision loss are static flowcharts that do not provide dynamic, stepwise workups. We tested the accuracy of a novel dynamic Bayesian algorithm loss. Seventy-nine "participants" with in Windsor, Canada were assessed by an emergency medicine or primary care provider who completed questionnaire about ocular symptoms/findings (without requiring fundoscopy). An ophthalmologist then attributed independent "gold-standard diagnosis". employed data to produce...

10.3390/vision6020021 article EN cc-by Vision 2022-04-04

Anti-vascular endothelial growth factor (VEGF) is the mainstay of treatment for several visually debilitating diseases and considered standard care a number conditions which may affect younger patients, including women childbearing age. These commonly include, but are not restricted to, diabetic macular edema (DME), proliferative retinopathy (PDR) myopic choroidal neovascularization (CNV). As in other areas medicine, pregnant breastfeeding often excluded from clinical trials due to unknown...

10.58931/cect.2023.2227 article EN cc-by-nc-nd Canadian Eye Care Today 2023-05-17

CRISPR-Cas9 is a novel gene-editing tool that promised to revolutionize our ability treat genetic conditions when first introduced. Today, it continues fuel many areas of health research, ranging from cancers sickle cell disease Huntington’s disease.1–3 Vision science researchers immediately saw the potential CRISPR, with some earliest experiments exploring CRISPR as treatment option for inherited ocular disorders.4 Only few years later, in March 2020, vision research was again at forefront...

10.5206/uwomj.v90i1.14009 article EN University of Western Ontario Medical Journal 2022-03-24

The current diagnostic aids for red eye are static flowcharts that do not provide dynamic, stepwise workups. accuracy of a novel dynamic Bayesian algorithm was tested. Fifty-seven patients with were evaluated by an emergency medicine physician who completed questionnaire about symptoms/findings (without requiring extensive slit lamp findings). An ophthalmologist then attributed independent "gold-standard diagnosis". used data to suggest differential diagnosis. referrer's 70.2%, while the...

10.3390/vision6040064 article EN cc-by Vision 2022-10-24

10.1016/j.jcjo.2022.11.009 article EN Canadian Journal of Ophthalmology 2022-12-05

Purpose: To report high toric intraocular lens (IOL) implantation in a patient with previous radial keratotomy and significantly flat corneal powers. Methods: Case report. Results: A 64-year-old woman bilateral 8-incision was referred for cataract surgery. Corrected distance visual acuity 20/70 the right eye counting fingers left (could not be refracted). The power of meridian below 30.00 diopters (D) bilaterally, so no IOL predictions were reported by standard biometric devices....

10.3928/jrscr-20221130-01 article EN Journal of Refractive Surgery Case Reports 2022-12-01
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