A5020546385- Schizophrenia research and treatment
- Metallic Glasses and Amorphous Alloys
- Galectins and Cancer Biology
- Thyroid Disorders and Treatments
- Diabetes Management and Research
- Adipokines, Inflammation, and Metabolic Diseases
- Adrenal and Paraganglionic Tumors
- Surface Roughness and Optical Measurements
- Gestational Diabetes Research and Management
- Magnetic Properties and Applications
- Human Health and Disease
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Thyroid Cancer Diagnosis and Treatment
- Vitamin D Research Studies
- Immune Cell Function and Interaction
- Mental Health Research Topics
- IL-33, ST2, and ILC Pathways
- Uterine Myomas and Treatments
- Pituitary Gland Disorders and Treatments
- Birth, Development, and Health
- Bipolar Disorder and Treatment
- Diabetes Treatment and Management
- Tryptophan and brain disorders
- Cancer, Hypoxia, and Metabolism
- Hormonal Regulation and Hypertension
University of Kragujevac
2015-2024
Clinical Centre of Kragujevac
2013-2024
National Medical Research Center of Cardiology
2024
Public Health Institute of the Republic of Srpska
2022
Klinika za Psihijatrijske Bolesti Dr Laza Lazarević
2016
Diabetes Australia
2013
Center for Clinical Research (United States)
2013
Paracelsus Medical University
2011
Military Technical Institute
2009
Institute of Technical Sciences of SASA
2008
Efficacy and safety of the glucagon-like peptide 1 (GLP-1) analog oral semaglutide sodium-glucose cotransporter 2 inhibitor empagliflozin were compared in patients with type diabetes uncontrolled on metformin.Patients randomized to once-daily open-label treatment 14 mg (n = 412) or 25 410) a 52-week trial. Key end points change from baseline week 26 HbA1c (primary) body weight (confirmatory secondary). Two estimands addressed efficacy-related questions: policy (regardless trial product...
Obesity-induced diabetes is associated with low-grade inflammation in adipose tissue and macrophage infiltration of islets. We show that ablation galectin-3 (Gal-3), a galactoside-binding lectin, accelerates high-fat diet–induced obesity diabetes. Obese LGALS3−/− mice have increased body weight, amount total visceral (VAT), fasting blood glucose insulin levels, homeostasis model assessment resistance, markers systemic compared diet-matched wild-type (WT) animals. VAT obese exhibited...
To achieve greater sustainability of the traffic system, trend accidents in road was analysed. Injuries from are among leading factors suffering people around world. predicted to be third factor contributing human deaths. Road have decreased most countries during last decade because Decade Action for Safety 2011–2020. The main reasons behind reduction improvements construction vehicles and roads, training education drivers, advances medical technology care. primary objective this paper is...
2 , Zorica Lazic 3 Vladimir Jakovljevic 4 Aleksandar Đukic 5 Radmila Velickovic 6 Mirjana Antunovic 7 1 Katedra za farmakologiju i toksikologiju, Medicinski fakultet Univerziteta u Kragujevcu Klinika psihijatriju, Klinicki centar Kragujevac internu medicinu, Centar plucne bolesti, Institut fi ziologiju, endokrinologiju, dijabetes I bolesti metabolizma, Odsek farmacija, Nisu farmaciju, Vojnomedicinska akademija Beograd
The purpose of this study was to examine functional capacity cardio-respiratory system in patients with schizophrenia, and evaluate the effects 12 weeks prescribed physical activity on aerobic symptoms schizophrenia.Study involved 80 hospitalized any subtypes schizophrenia (42 men, 38 women). They were divided into two groups: exercise control group, both 40 patients. Maximal (VO2 max) as an indicator cardiovascular fitness has been obtained by cardiopulmonary stress test a treadmill. Twelve...
Background/Aim. Mental health of university students is under increasing concern worldwide, because they face challenges which predisposes them to depression and anxiety. The aim this study was identify demographic socioeconomic variables associated with depressive anxiety symptoms among students. Methods. This cross-sectional on 1,940 performed using a questionnaire including variables, Beck Depression Inventory Anxiety Inventory. Results. prevalence in 23.6%, while the 33.5%. were...
Background Ulcerative colitis (UC) is a chronic disease characterized by inflammation of intestinal epithelium, primarily the colon. An increasing prevalence metabolic syndrome (MetS) in patients with UC has been documented recently. Still, there no evidence that MetS alters course UC. Aim To test influence on severity and local systemic immune status. Methods Eighty nine de novo histologically confirmed were divided two groups, according to ATP III criteria: Group without (no MetS) group...
Aims/hypothesis: Galectin 3 appears to have proinflammatory role in several inflammatory and autoimmune diseases. Also, there is evidence that galectin plays a both, type 1 2 diabetes. During obesity hematopoetic cells-derived induces insulin resistence. While the of expressed islet invading immune cells both diabetes has been studied, importance expression this molecule on target pancreatic beta not defined. Methods: To clarify during obesity-induced diabetogenesis, we developed transgenic...
The cells of the innate and adaptive immune systems have been implicated in development obesity-induced metaflammation metabolic disorders including type 2 diabetes. Galectin-3, a β-galactoside-binding lectin, modulates immune/inflammatory responses specifically binds to advanced glycation end products (AGE), modified lipoproteins, endotoxin. In recently published study we demonstrate proinflammatory changes visceral adipose tissue pancreatic islets galectin-3-deficient mice fed high-fat...
In this paper, we present two DC-DC converters that operate at a microwave frequency. The first converter consists of class-E switched-mode amplifier, which performs the DC-AC conversion, and half-wave diode rectifier outputs. MESFET amplifier has minimum power-added efficiency 86%, corresponding drain 95%, 120 mW output power 4.5 GHz. maximum conversion 98% an overall 83%. second high-efficiency oscillator rectifier. 57% 725 mW. is planar compact, with no magnetic components, 64% for DC...
Abstract Measurement of serum thyroglobulin (Tg) is a highly specific test in the management patients with differentiated thyroid cancer (DTC) after surgical treatment. The aim our study was to evaluate and compare Tg levels these found by radioimmunoassay (RIA) immunoradiometric assay (IRMA) assess influence antibodies (TgAbs) on values obtained for concentration. Both TgAb were determined postoperatively 71 DTC using RIA Tg‐PEG (INEP) IRMA (CIS) Tg, together circulating endogenous...
Smoke derived from combustible cigarettes (CCs) contains numerous harmful chemicals that can impair the viability, proliferation, and activation of immune cells, affecting progression chronic inflammatory diseases. In order to avoid detrimental effects cigarette smoking, many CC users have replaced CCs with heated tobacco products (HTPs). Due different methods processing, CC-sourced smoke HTP-derived aerosols contain chemical constituents. With exception nicotine, HTP-sourced significantly...
Background and aim: N terminal-proB-type natriuretic peptide (NT-proBNP) is synthesised secreted from the ventricularmyocardium. This marker known to be elevated in patients with acute coronary syndromes (ACS). We evaluated NT-proBNP asa significant diagnostic an important independent predictor of short-term mortality (one month) ACS. Methods: cardiac troponin I (cTI) were assessed 134 consecutive (median age 66 years, 73% male)hospitalised for ACS a cardiological university department. The...
Background/Aim. Professional military personnel are exposed to a number of stressors during the war as well in peacetime conditions that can cause some hidden or manifest disorders, especially anxiety and depression, but also development burnout syndrome. The aim our investigation was determine defense mechanisms subjective assessment quality life professional Serbian Armed Forces with Methods. cross-sectional study included total 55 personnel, from 25 years age, without current mental...
Objectives: To evaluate the effect of cigarette smoking and heavy coffee consumption on efficacy safety olanzapine treatment in schizophrenia patients, relation to genetic polymorphism.Methods: The study involved 120 patients with schizophrenia, treated for 30 days. Therapy was determined using three different psychiatric scales, by assessing metabolic adverse effects extrapyramidal symptoms. Genotyping included CYP1A2*1C, CYP1A2*1F CYP1A1/1A2 intergenic polymorphism, as well CYP2D6*3,...
Powder mixture of 50 mass % barium titanate (BaTiO3) and iron (Fe) was prepared by solid-state reaction technique, i.e. ball milled in air for 60 min, 80 100 120 min 150 min. During mechanochemical activation it observed the powder transitsion to oxides. Depending on time content oxides FeO, Fe2O3 Fe3O4 varies. Simultaneously, with change activated system, magnetic properties as well. The XRD analysis samples shown that increase, oxide percentage increases to, whereby BaTiO3 a total sample...
Adiponectin is one of the most important molecules in body's compensatory response to development insulin resistance. By trying maintain sensitivity, increase secretion and prevent inflammation, adiponectin tries glucose homeostasis. Interleukin-33, which belongs group alarmins, also promotes secretion. Interleukin-33 might be either pro-inflammatory or anti-inflammatory depending on disease model. However, interleukin-33 has shown various protective effects CVD, obesity diabetes. The aim...
Introduction Peptide receptor radionuclide therapy (PRRT) is a treatment option for well-differentiated, somatostatin positive, unresectable or/and metastatic neuroendocrine tumors (NETs). Although high disease control rates seen with PRRT significant number NET patients have short progression-free interval, and currently, there deficiency of effective biomarkers to pre-identify these patients. This study aimed at determining the prognostic significance on survival NETs in initial treatment....
Almost all individual antipsychotics are classified into the intermediate pregnancy risk category as no or limited data exist about human outcomes. We presented case of zuclopenthixol decanoate using in two successive pregnancies same woman, which had not been published available peer-reviewed literature. A middle-age female subject who suffered from schizophrenia received injection during her consecutive pregnancies. About four and a half months before diagnosis first (to approximately 3.5...