A5051897522- Toxic Organic Pollutants Impact
- Effects and risks of endocrine disrupting chemicals
- Air Quality and Health Impacts
- Analytical Chemistry and Chromatography
- Advanced Chemical Sensor Technologies
- Per- and polyfluoroalkyl substances research
- Indoor Air Quality and Microbial Exposure
- Analytical chemistry methods development
- Carcinogens and Genotoxicity Assessment
- Mass Spectrometry Techniques and Applications
- Environmental Toxicology and Ecotoxicology
- Microfluidic and Capillary Electrophoresis Applications
- Occupational exposure and asthma
- Mercury impact and mitigation studies
- Heavy metals in environment
- Chromium effects and bioremediation
- Water Quality Monitoring and Analysis
- Atmospheric chemistry and aerosols
- Microbial bioremediation and biosurfactants
- Recycling and Waste Management Techniques
- Pesticide Residue Analysis and Safety
- Intravenous Infusion Technology and Safety
- Occupational Health and Performance
- Noise Effects and Management
- Metabolomics and Mass Spectrometry Studies
Örebro University
2015-2025
The use of a new atmospheric-pressure chemical ionization source for gas chromatography (APGC) coupled with tandem quadrupole mass spectrometry (MS/MS) system, as an alternative to high-resolution (HRMS), the determination PCDDs/PCDFs is described. potential using (APCI) analyzer has been validated identification and quantification dioxins furans in different complex matrices. main advantage APCI soft at atmospheric pressure, which results very limited fragmentation. spectra are dominated by...
The H4IIE-luc transactivation bioassay for aryl hydrocarbon receptor (AhR) agonists was used to investigate the relative potency factors (REPs) of 22 individual polycyclic aromatic hydrocarbons (PAHs) and their oxygenated-, methylated-, N-containing derivatives (azaarenes), which are often present in PAH-contaminated soils. Naphthacene dibenz[ah]acridine exhibited greater AhR-mediated potency, whereas lesser molecular-weight azaarenes were less potent AhR agonists. Six oxygenated PAHs had...
Objectives Exposure to high-molecular-weight polycyclic aromatic hydrocarbons (PAHs) may cause cancer in chimney sweeps and creosote-exposed workers, however, knowledge about exposure low-molecular-weight PAHs relation risk is limited. In this study, we aimed investigate occupational the phenanthrene fluorene different biomarkers. Methods We recruited 151 sweeps, 19 workers 152 unexposed (controls), all men. measured monohydroxylated metabolites of urine using liquid chromatography coupled...
Some polycyclic aromatic hydrocarbons (PAH) are known carcinogens and workplace PAH exposure may increase the risk of cancer. Monitoring early cancer-related changes can indicate whether is carcinogenic. Here, we enrolled 151 chimney sweeps, 152 controls 19 creosote-exposed male workers from Sweden. We measured urinary metabolites using LC/MS/MS, markers telomere length (TL) mitochondrial DNA copy number (mtDNAcn) qPCR, methylation lung genes F2RL3 AHRR pyrosequencing. The median...
Hexavalent chromium (Cr(Ⅵ)) is classified as a group 1 human carcinogen and increases the risk of lung cancer. Non-coding RNAs (ncRNAs) have key regulatory roles in cancer, but less known about their relation to Cr(Ⅵ) exposure.
Children are exposed to endocrine disrupting chemicals (EDCs) through inhalation and ingestion, as well dermal contact in their everyday indoor environments. The loadings of EDCs may contribute significantly children's total EDC exposure due absorption hand-to-mouth behaviors. aim this study was measure potential EDCs, specifically halogenated flame retardants (HFRs) organophosphate esters (OPEs), on hands during preschool attendance assess possible determinants environments Sweden. For...
A selective and fast method for the quantitative determination of 2,4,6-trichloroanisole (TCA) 2,4,6-tribromoanisole (TBA) in wine was developed. Microextraction packed syringe (MEPS) optimized extraction preconcentration analytes using extremely small volume samples (0.1-1 mL). For GC-EI-MS, limit detection (LOD) red white range 0.17-0.49 microg L(-1) TCA TBA. In addition to GC-EI-MS both GC-NCI-MS GC-HRMS were used further improve selectivity sensitivity. The lowest LODs achieved EI mode....