Low-cost, robust, and reusable continuous glucose monitoring systems that can provide quantitative measurements at point-of-care settings is an unmet medical need. Optical sensors require complex time-consuming fabrication processes, their readouts are not practical for analyses. Here, a wearable contact lens optical sensor was created the quantification of physiological conditions, simplifying process facilitating smartphone readouts. A photonic microstructure having periodicity 1.6 μm...

Phenylboronic acids have emerged as synthetic receptors that can reversibly bind to cis-diols of glucose molecules. The incorporation phenylboronic in hydrogels offers exclusive attributes; for example, the binding process with induces Donnan osmotic pressure resulting volumetric changes matrix. However, their practical applications are hindered because complex readout approaches and time-consuming fabrication processes. Here, we demonstrate a microimprinting method fabricate densely packed...

Fiber‐optic technology emerged originally for applications in data transmission and telecommunications. However, sensors based on fiber‐optics have been developed rapidly because of their excellent sensing performances capability to function remote harsh environments. The usage fiber‐optic has flourished many fields over the past 30 years due fiber‐optic's inherent advantages: cost‐effectiveness, miniaturized size, light weight, immunity electromagnetic interference. This work reviews Bragg...

This review covers recent advances in optical sensors, which can continuously monitor glucose levels for point-of-care diagnosis of diabetes.

Color vision deficiency (CVD) is an ocular congenital disorder that affects 8% of males and 0.5% females. The most prevalent form color (color blindness) protans deutans more commonly known as "red-green blindness". Since there no cure for this disorder, CVD patients opt wearables aid in enhancing their perception. common wearable used by a tinted glass/lens. Those glasses filter out the problematic wavelengths (540-580 nm) red-green using organic dyes. However, few studies have addressed...

Although the manufacturing processes of contact lenses are well established, use additive for their fabrication opens many new possibilities to explore. The current study demonstrates personalized smart contract utilizing manufacturing. includes 3-dimensional (3D) modeling with assistance a computer aided designing tool based on standard commercial lens dimension, followed by selection suitable materials and 3D printing lenses. parameters were optimized achieve desired geometries, post...

Paper microfluidic sensors were integrated into laser-inscribed contact lenses to provide an <italic>in situ</italic> platform for tear analysis with smartphone readouts.

The benefits of enclosing pH sensors into wound dressings include treatment monitoring wounded skin and early detection developing chronic conditions, especially for diabetic patients. A 3D printed re-entrant auxetic hydrogel dressing, doped with indicator phenol red dye, was developed characterized. design allows dressing adhesion to complex body parts, such as joints on arms legs. Tensile tests revealed a yield strength 140 kPa Young's modulus 78 MPa. In addition, the 3D-printed has...

Constant exposure to blue light emanating from screens, lamps, digital devices, or other artificial sources at night can suppress melatonin secretion, potentially compromising both sleep quality and overall health. Daytime elevated levels of also lead permanent damage the eyes. Here, we have developed protective plasmonic contact lenses (PCLs) mitigate exposure. Crafted poly(hydroxyethyl methacrylate) (pHEMA) infused with silver nanoparticles, these serve as a barrier filter light....

Anthocyanins are bioactive compounds naturally found in a variety of leaves, fruits, and vegetables. Anthocyanin pigments undergo modification their chemical structure when exposed to different concentrations hydrogen ions, they were extensively studied be used as active elements biocompatible pH sensors. The ocular is significant parameter assess the physiology cases postocular surgery, keratoconjunctivitis, rosacea. Contact lenses have potential medical diagnostic devices for situ...

Color vision deficiency (color blindness) is an inherited genetic ocular disorder. While no cure for this disorder currently exists, several methods can be used to increase the color perception of those affected. One such method use filtering glasses which are based on Bragg filters. these effective, they high cost, bulky, and incompatible with other correction eyeglasses. In work, a rhodamine derivative incorporated in commercial contact lenses filter out specific wavelength bands (≈545-575...

Temperature variation is a ubiquitous medical sign to monitor ocular conditions including dry eye disease (DED), glaucoma, carotid artery stenosis, diabetic retinopathy, and vascular neuritis. The ability measure OST in real time desirable point-of-care diagnostics. Here, we developed minimally invasive contact lens temperature sensors for continuous monitoring of the corneal temperature. sensor consisted laser patterned commercial embedding temperature-sensitive Cholesteric Liquid Crystals...

The applications of optical fibers are impeded in implantable medical diagnostics due to incompatibility with biological tissues, and immune reaction vivo. utilization biocompatible materials construct a photonic sensing platform can reduce the response vivo diagnostics. Here, we developed real-time fiber sensors determine volumetric modulation stimuli-responsive polymers. Asymmetric microlens structures were replicated on stimuli-sensitive hydrogels as stand-alone chemically attached tips...

Abstract Color vision deficiency (CVD) or color blindness is an ocular disorder that hinders the patients from distinguishing shades of certain colors. blind are often not considered for critical occupations (e.g., military, police) and cannot differentiate colors in public places media (i.e., watching TV). The most common form red‐green, which a result either missing defective red green photoreceptor cone. Since no cure this exists, sufferers opt methods to enhance their perception....

Additive manufacturing (3D printing) has the ability to architect structures at microscale, giving rise development of functional contact lenses (CLs) with inbuilt sensing capabilities. 3D printing technology enables fabrication CLs without surface geometry restrictions. Spherical, nonspherical, symmetric, and asymmetric can be manufactured in an integrated production process. Advantages over conventional techniques include fast easy production, one‐step manufacturing, no post processing...

Commercial implantable continuous glucose monitoring devices are invasive and discomfort. Here, a minimally-invasive detection system is developed to provide quantitative measurements continually based on bifocal contact lenses. A glucose-sensitive phenylboronic acid derivative immobilized in hydrogel matrix the surface of imprinted with Fresnel lens. The glucose-responsive attached commercial soft lens be transformed into showed lengths; far-field focal length originated from lens'...

Contact lenses can be functionalized to offer advanced capabilities transcending their primary applications in vision correction and cosmetics. Herein, 40 60 nm spherical silver nanoparticles (SNPs) are integrated within poly(2‐hydroxyethyl methacrylate) (pHEMA) contact toward fabrication of SNP‐loaded with excellent optical material properties as wearables for blue‐yellow color deficiency (CVD) patients. The morphology the SNPs characterized prepolymerization using transmission electron...