A5075028515- Biosensors and Analytical Detection
- Advanced biosensing and bioanalysis techniques
- Advanced Nanomaterials in Catalysis
- Luminescence and Fluorescent Materials
- Luminescence Properties of Advanced Materials
- Nanoplatforms for cancer theranostics
- Electrochemical sensors and biosensors
- Carbon and Quantum Dots Applications
- Advanced Chemical Sensor Technologies
- Spectroscopy Techniques in Biomedical and Chemical Research
- Mercury impact and mitigation studies
- Advanced Photocatalysis Techniques
- Forensic Fingerprint Detection Methods
- Electrochemical Analysis and Applications
- Alkaline Phosphatase Research Studies
- thermodynamics and calorimetric analyses
- Mass Spectrometry Techniques and Applications
- Neuroinflammation and Neurodegeneration Mechanisms
- Gas Sensing Nanomaterials and Sensors
- Spectroscopy and Chemometric Analyses
- Gold and Silver Nanoparticles Synthesis and Applications
- Analytical chemistry methods development
- Analytical Chemistry and Sensors
- MicroRNA in disease regulation
- Quantum Dots Synthesis And Properties
University of South China
2020-2024
Hunan University
2017-2020
Institute of Pharmacology
2020
Hengyang Academy of Agricultural Sciences
2020
State Key Laboratory of Chemobiosensing and Chemometrics
2018-2019
Changsha University
2019
New strategies for the simultaneous and portable detection of multiple enzyme activities are highly desirable clinical diagnosis home care. However, methods developed thus far generally suffer from high costs, cumbersome procedures, heavy reliance on large-scale instruments. To satisfy actual requirements rapid, accurate, on-site activities, we report herein a smartphone-assisted programmable microfluidic paper-based analytical device (μPAD) that utilizes colorimetric photothermal signals...
Due to their unique properties, rare-earth doped upconversion luminescence (UCL) nanomaterials are of considerable scientific interest. Meanwhile, alkaline-earth sulfide materials based on a completely different electron trapping (ET) mechanism demonstrate extremely high UCL efficiencies, which several dozens times more than those conventional fluoride nanomaterials. However, the large particle size, easy hydrolysis, and difficulty in achieving uniform dispersion have precluded bioassay...
Developing ultrasensitive lateral flow immunoassays (LFIAs) has garnered significant attention in the field of point-of-care testing. In this study, a trimetallic dendritic nanozyme (Pd@Pt–Ru) was synthesized through Ru deposition on Pd@Pt core and utilized to enhancing sensitivity LFIAs. Pd@Pt–Ru exhibited Km value 5.23 mM for detecting H2O2, which indicates an H2O2 affinity comparable with that horseradish peroxidase. The surface layer reduces activation energy barrier, increases maximum...
The multiple-metal-nanoparticle tagging strategy has generally been applied to the multiplexed detection of multiple analytes interest such as microRNAs (miRNAs). Herein, it was used for first time improve both specificity and sensitivity a novel mass spectroscopic platform miRNA detection. developed through integration ligation reaction, hybridization chain reaction amplification, tagging, inductively coupled plasma spectrometry. high resulted from adoption is further enhanced by strategy....
Sub-10 nm monodisperse alkaline-earth sulfide nanodots (ASNDs) with bright near-infrared (NIR)-excitation fluorescence and adjustable emission wavelength were prepared by a thermal decomposition method for the first time. The ASNDs exhibited high NIR-to-vis conversion efficiency served as multicolor fluorescent labels in proposed miR-224 assay. Targeted detection of level single-nucleotide variation was carried out on smartphone-based platform using hybridization chain reaction (HCR)...
Bright Ln<sup>3+</sup>-doped CaS/SrS near-infrared stimulated luminescent nanoparticles with variable fluorescent emission colors were successfully prepared.
The simultaneous analysis of diversified biomarkers with high sensitivity and in a point-of-care (POC) manner is great significance for facile early cancer diagnosis. Herein, we develop target amplification-assisted ratiometric fluorescence assay (TARFA) platform integrating the dual-amplification strategy colorimetric readout technology sensitive specific detection two malignancy-associated biomarkers. Meanwhile, NIR-excited alkaline-earth sulfide nanodots (ASNDs) an ultrasmall (<10 nm)...
Eu,Sm,Mn-doped CaS (ESM-CaS) nanoparticles demonstrate a remarkable upconversion luminescence (UCL) efficiency with quantum yield of nearly 60%, enabling many new applications and devices. We describe an ESM-CaS nanoparticle-based paper test strip for one-shot quantitative measurement sulfite concentration using smartphone-based reader. The integrated UCL-based detection system features high sensitivity facile operation without the need separation pretreatment. Moreover, design principles...
In this paper, nitrogen-doped carbon dots (NCDs) were synthesized via a facile hydrothermal method using gum arabic (GA) and tris(hydroxymethyl)methyl aminomethane (tris) as precursors.
Ultra-bright CaS and SrS fluorescent nanoprobes coupling magnetic ZnFe<sub>2</sub>O<sub>4</sub> nanoparticles applied in bacteria quantitative sensing naked-eye analysis.
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