A5073996330- Ocular Surface and Contact Lens
- Advanced Drug Delivery Systems
- Circadian rhythm and melatonin
- Sleep and Wakefulness Research
- Medicinal Plants and Bioactive Compounds
- TiO2 Photocatalysis and Solar Cells
- COVID-19 Clinical Research Studies
- Cholinesterase and Neurodegenerative Diseases
- Proteins in Food Systems
- Curcumin's Biomedical Applications
- Calcium Carbonate Crystallization and Inhibition
- Protein Interaction Studies and Fluorescence Analysis
- Phytochemicals and Antioxidant Activities
- Advanced Photocatalysis Techniques
- COVID-19 epidemiological studies
- Drug Solubulity and Delivery Systems
- Corneal Surgery and Treatments
- Genetics, Aging, and Longevity in Model Organisms
- Ocular Infections and Treatments
- Intraocular Surgery and Lenses
- Gold and Silver Nanoparticles Synthesis and Applications
- Antibiotics Pharmacokinetics and Efficacy
- Glaucoma and retinal disorders
- Global Public Health Policies and Epidemiology
- Quantum Dots Synthesis And Properties
Consejo Nacional de Investigaciones Científicas y Técnicas
2020-2025
Universidad Nacional de Córdoba
2020-2025
Universidad de Salamanca
2018
Neurodegenerative ocular diseases, such as age-related macular degeneration (AMD) and glaucoma, represent growing public health concerns. Oxidative stress plays a key role in their development, damaging retinal cells accelerating disease progression. Melatonin (Mel) is potent antioxidant with neuroprotective properties; however, it faces limitations low solubility. This study proposes the use of human serum albumin nanoparticles (Np-HSA) to enhance delivery Mel posterior segment eye...
Folic acid (FA) is essential for cellular functions but has limited ocular bioavailability, which restricts its therapeutic effectiveness. This study developed chitosan-based nanogels (NG) as FA carriers, evaluating their mucoadhesion, drug release, and corneal permeation. Freshly prepared NGs had a hydrodynamic diameter of 312.4 ± 8.2 nm polydispersity index (PdI) 0.28 0.04, determined by Dynamic Light Scattering (DLS). encapsulation was confirmed through Fourier Transform Infrared (FTIR)...
Background: Folic acid (FA) is essential for cellular functions but has limited ocular bioavailability, restricting its therapeutic effectiveness. Objective: To develop chitosan (CS)-based nanogels (NGs) FA transport and release, with corneal permeation evaluation. Methods: NGs’ hydrodynamic diameter (Ho) polydispersity index (PdI) were determined using dynamic light scattering (DLS). CS-FA interaction was confirmed by Fourier transform infrared (FTIR) spectroscopy, differential scanning...
Abstract Objective: In this work, in order to establish a better comprehension of the association between Argentina and its neighbor countries’ capacity, COVID-19 burden during first 3 months, different indicators were evaluated. Method: We analyzed GHSI, INFORM index (number confirmed cases deaths), also number tests, lethality stringency Governmental policies Results: Uruguay, Paraguay, Bolivia started earlier prevention measures. The tests differs, as Chile is 1 that makes more. Uruguay...
Objective: Develop sterile vancomycin-amikacin reinforced antibiotics in smaller batches of finished products than those produced at the industrial level and under different working conditions.In this work, critical aspects concerning elaboration process such as equipment evaluation, protocol development, physicochemical characterization, microbiological tests were analyzed.In first stage, preparation formulations was carried out Department Pharmaceutical Sciences Faculty Chemical National...