Alexander N. Berk

ORCID: 0000-0003-4161-7747
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About
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Research Areas
  • Shoulder Injury and Treatment
  • Total Knee Arthroplasty Outcomes
  • Knee injuries and reconstruction techniques
  • Shoulder and Clavicle Injuries
  • Orthopedic Surgery and Rehabilitation
  • Sports injuries and prevention
  • Pelvic and Acetabular Injuries
  • Nerve Injury and Rehabilitation
  • Injury Epidemiology and Prevention
  • 3D Printing in Biomedical Research
  • Elbow and Forearm Trauma Treatment
  • Abdominal Trauma and Injuries
  • Mesenchymal stem cell research
  • Nerve injury and regeneration
  • Lower Extremity Biomechanics and Pathologies
  • Tissue Engineering and Regenerative Medicine
  • Orthopedic Infections and Treatments
  • Respiratory Support and Mechanisms
  • Social Media in Health Education
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Nutrition and Health in Aging
  • Anatomy and Medical Technology
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Trauma Management and Diagnosis
  • Foot and Ankle Surgery

OrthoCarolina
2023-2025

OrthoCarolina Research Institute
2023-2025

University Hospitals of Cleveland
2025

Case Western Reserve University
2022-2025

University School
2025

Carolina Musculoskeletal Institute
2023-2024

University Medical Center of the Johannes Gutenberg University Mainz
2024

Johannes Gutenberg University Mainz
2024

University of Minnesota
2023

University Physicians
2023

The prevalence of dementia and other neurodegenerative diseases continues to rise as age demographics in the population shift, inspiring development long-term tissue culture systems with which study chronic brain disease. Here, it is investigated whether a 3D bioengineered neural model derived from human induced pluripotent stem cells (hiPSCs) can remain stable functional for multiple years culture. Silk-based scaffolds are seeded neurons glial hiPSCs supplied by donors who either healthy or...

10.1002/mabi.202000004 article EN Macromolecular Bioscience 2020-02-17

Abstract Traumatic brain injury (TBI) survivors suffer long term from mental illness, neurodegeneration, and neuroinflammation. Studies of 3D tissue models have provided new insights into the pathobiology many diseases. Here, a in vitro contusion model is developed consisting mouse cortical neurons grown on silk scaffold embedded collagen used outcomes an vivo for benchmarking. Molecular, cellular, network events are characterized response to controlled impact (CCI). In this model, CCI...

10.1002/adhm.202000122 article EN Advanced Healthcare Materials 2020-05-13

Background: High tibial osteotomy (HTO) and distal femoral (DFO) are well-recognized treatments to address varus valgus malalignment, respectively, in the setting of symptomatic unicompartmental arthritis tibiofemoral joint. The existing literature is limited its ability characterize complications after HTO or DFO procedures. Purpose: objective this study was determine rate early (≤90 days) postoperative associated variables from 15-year experience a single academic institution. Study...

10.1177/03635465231183092 article EN The American Journal of Sports Medicine 2023-07-07

Background: Surfing is an increasingly popular sport with a high propensity for both traumatic and atraumatic injuries. Purpose: To analyze the trends, etiologies, diagnoses of lower extremity orthopaedic-related surfing injuries presenting to United States (US) emergency departments (EDs) within 21-year study period. Study Design: Descriptive epidemiology study. Methods: The National Electronic Injury Surveillance System database was queried data on US EDs from January 1 December 31, 2022....

10.1177/23259671241237289 article EN cc-by-nc-nd Orthopaedic Journal of Sports Medicine 2024-04-01

Abstract Background There are no studies that compare the outcomes and complications of single-versus two-stage revision anterior cruciate ligament reconstruction (ACLR) after primary ACLR failure. This purpose this study is to examine clinical functional associated with single Methods All patients who underwent or failure between 2012 2021 a minimum 2 year follow-up were included. Patients excluded if they not treated at our academic institution, had inadequate follow-up, incomplete medical...

10.1186/s43019-024-00257-y article EN cc-by Knee Surgery and Related Research 2025-01-15

Purpose The purpose of this study is to assess the long-term clinical complications, outcomes, and return sport (RTS) rates in patients aged 30 or younger with a primary full-thickness arthroscopic rotator cuff repair (ARCR). Methods All who underwent ARCR at age years from 2003 2021 minimum 2-year follow-up were included. Complications, repeat surgeries, collected. Results 32 mean 9.3[2.7–17.9] years. 5(15.6%) had postoperative shoulder stiffness, persistent pain was reported 4(12.5%)...

10.1177/17585732241312192 article EN Shoulder & Elbow 2025-01-12

Background: Tibial tubercle osteotomy (TTO) is a well-established surgical treatment option for patients with patellofemoral disorders. Purpose: To determine the rate of early (≤90 day) postoperative complications after TTO and variables related to complications. Study Design: Case series; Level evidence, 4. Methods: Patients who underwent at single academic institution within 15-year period (2008-2022) were identified. All minimum 90-day follow-up considered study inclusion. Exclusion...

10.1177/23259671231194367 article EN cc-by-nc-nd Orthopaedic Journal of Sports Medicine 2023-10-01

Introduction While awake tracheal intubation (ATI) is regarded as the gold standard for difficult airway management according to current guidelines, there seems be a reluctance in its application. This retrospective cohort study, conducted at German tertiary hospital over 2-year period, aimed demonstrate that integrating using flexible bronchoscopy (ATI:FB) into routine makes it successful and safe approach. Materials methods In 2019 2020, records from data acquisition system (DAQ) archived...

10.1371/journal.pone.0299071 article EN cc-by PLoS ONE 2024-03-01

A novel hybrid transtibial (HTT) approach to femoral tunnel drilling in anterior cruciate ligament reconstruction (ACLR) has been developed that circumvents the need for knee hyperflexion and orients graft most anatomic position without sacrificing length or aperture.

10.1177/23259671241242778 article EN cc-by-nc-nd Orthopaedic Journal of Sports Medicine 2024-06-01

Background The objective of this study was to retrospectively report on the outcomes female patients undergoing Latarjet procedure. Methods Female procedure with minimum 1 year follow-up were identified and contacted obtain Numeric Pain Rating Scale (NPRS), Subjective Shoulder Value (SSV), return sport (RTS) data. Eligible females then matched 1:1 a male counterpart based laterality age (± 3 years), compared. Results A total 20 mean 73.8 months reported postoperative NPRS SSV scores 2.2 ±...

10.1177/17585732231217170 article EN Shoulder & Elbow 2023-11-27

Objectives: Despite nearly 30% of first-time anterior shoulder dislocations occurring in females, little has been reported on the outcomes female patients with recurrent instability and bone loss. Stabilization surgery via Latarjet procedure can reduce risk dislocation improve patient quality life. Prior studies have focused high-risk subgroups, such as young males who play contact sports, there thus remains a paucity data regarding female-specific outcomes. The limited stabilization...

10.1177/2325967123s00175 article EN cc-by-nc-nd Orthopaedic Journal of Sports Medicine 2023-07-01
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