A5036375943- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Synthesis and biological activity
- Sesquiterpenes and Asteraceae Studies
- Synthesis of Organic Compounds
- Phytochemicals and Antioxidant Activities
- Synthesis and Biological Evaluation
- Multicomponent Synthesis of Heterocycles
- Plant biochemistry and biosynthesis
- Synthesis and Characterization of Heterocyclic Compounds
- Bioactive Compounds and Antitumor Agents
- Bee Products Chemical Analysis
- Marine Sponges and Natural Products
- Free Radicals and Antioxidants
- Plant Ecology and Taxonomy Studies
- Echinoderm biology and ecology
- Synthesis and Reactions of Organic Compounds
- Plant chemical constituents analysis
- Molecular Sensors and Ion Detection
- Plant and animal studies
- Phytochemical compounds biological activities
- Bryophyte Studies and Records
- Insect and Pesticide Research
- Lichen and fungal ecology
Karadeniz Technical University
2016-2025
Istanbul University
2017
University of Kara
2007
GTx (United States)
2007
Sakarya University
2006
Commercial blueberry production has been a viable industry throughout the world for 95 years; because of is good source antioxidant. Blueberries are especially rich in anthocyanin, flavonoid with potent antioxidant capacity. The aim this study was to compare phenolic quantities, activities, sugar and compounds blueberries produced Turkey those similar varieties around world. As result conducted analysis, total content (TPC) amount found berries 77.26-215.12 mg GAE/100 g, (TFC) 30.44-91.69...
An efficient method was developed for the simultaneous determination of Sunset Yellow FCF (E110), Allura Red AC (E129), Quinoline WS (E104), and Tartrazine (E102) in food samples by RP-HPLC. The mentioned dyes were analyzed at room temperature 23 min with gradient elution. Three mobile phases used elution, phase A an acetate buffer (pH = 7.5, 1%), B acetonitrile, C methanol. flow rate 1.0 mL −1 , injection volume 20 µ L. linear ranges 0.72–50 mg L 0.24–50 0.75–10 0.69–50 Tartrazine, WS, FCF,...
Design and synthesis of a new type bischalcones as an alternative to natural synthetic are reported for the first time. Key steps involved solvent-free Claisen-Schmidt condensation chalcones, successful application diazotization-diazocoupling reaction in CNNC-linked by simple structural modification p-aminoacetophenone. The structures all compounds were confirmed means FT-IR, (1) H (13) C NMR, ESI/MS, elemental analysis. In addition, newly synthesized screened carbonic anhydrase...
Imatinib, an Abelson (ABL) tyrosine kinase inhibitor, is a lead molecular-targeted drug against chronic myelogenous leukemia (CML). To overcome its resistance and adverse effects, new inhibitors of ABL are needed. Our previous study showed that the benzyl ester gypsogenin (1c), pentacyclic triterpene, has anti-ABL subsequent anti-CML activity. optimize activities, esters carefully selected triterpenes (PT1-PT6), from different classes comprising oleanane, ursane lupane, substituted (GP1-GP5)...
Abstract Lamiaceae, a family of flowering plants, have been historically used as culinary herbs, shrubs and medicinal plants. With this study, the volatile organic compounds (VOCs) five species Lamiaceae ( Thymus cilicicus , Clinopodium nepeta L., Nepeta italica Thymbra spicata L. Ziziphora clinopodioides ) that grow in Turkey were identified by SPME/GC‐FID/MS method. The screened order to reveal their antibacterial antioxidant activities. Phenolic compound analyses performed using RP‐HPLC...
Glioma, particularly its most malignant form, glioblastoma multiforme (GBM), is the common and aggressive central nervous system tumor. The drawbacks of current chemotherapy for GBM have aroused curiosity in search targeted therapies. Aberrantly overexpressed epidermal growth factor receptor (EGFR) results poor prognosis, low survival rates, responses to therapy recurrence, therefore EGFR-targeted stands out as a promising approach treatment gliomas. In this context, series pentacyclic...
Herein, two iridoid glucosides aucubin (1) and ajugol (2), phenyl ethanoids, verbascoside (3) poliumoside (4) were isolated from the methanol extract of aerial parts Verbascum speciosum used to study about their anticancer activity for first time. The structures all compounds elucidated using spectroscopic data (IR, 1D 2D NMR, LC-TOF/MS). Antiproliferative activities Aucubun Verbascoside tested against A-549 (human colon cancer), MDA-MD-453 breast cancer) 3T3-L1 (mouse fibroblast)cell lines...
Volatile organic compounds (VOCs) of essential oils (EOs) and solid phase microextract (SPME) obtained from the flower, leaf, stem Epilobium angustifolium L. were analyzed by GC-FID/MS. The EOs SPMEs consist mainly monoterpenes aldehydes, which are major classes compounds. Limonene was found to be a compound in flower (HD: 42.9% vs. SPME: 95.5%), leaf 60.3% 4.7%), 49.06% 93.6%). antimicrobial activity solvent extracts (n-hexane, acetonitrile, methanol) E. screened vitro against nine...
ABSTRACT This study aimed to determine the essential oils (EOs), phenolic content, and antimicrobial activity of Vicia bithynica L. V. cracca subsp. . The chemical composition EOs was identified by gas chromatography‐mass spectroscopy analysis. significant components occurring in EO were ( E )‐ β ‐ocimine (24.7%) 2‐ethylfuran (27.3%), respectively. contents for methanol extracts analyzed high‐performance liquid chromatography, sinapic acid (1.69 0.31 mg/g, respectively) main compound....
The composition of the essential oils obtained from air-dried Teucrium chamaedrys. L. subsp. chamaedrys., orientale. var. puberulens., and lydium. (Lamiaceae) were analyzed by GC-MS. Thirty-six, 35, 33 components identified in oils, germacrene D (16.7%) was most abundant constituent T. β-caryophyllene component both puberulens. ratios 21.7% 19.7%, respectively. isolated plants tested for antimicrobial activity showed moderate antibacterial against Gram-positive Gram-negative bacteria, but no...
The chemical components and antimicrobial activity of the essential oils from Centaurea appendicigera C. Koch helenioides Boiss, two different endemic members genus L. (Asteraceae), were studied. air-dried obtained by hydrodistillation in a Clevenger-type apparatus analyzed GC-MS. Forty-five fifty-one identified helenioides, respectively, main these taxa found to be β-caryophyllene (17.5%) caryophyllene oxide (18.2%) helenioides. isolated oil plants was also investigated, demonstrated...
Abstract A simple environmentally friendly solid‐phase microwave‐assisted method was used to synthesis of the 1,3′‐diazaflavanone ( 2 ) and 1,3′‐diazaflavone 3 from cyclization 2′‐amino E )‐3″‐azachalcone 1 ). Ten new N ‐alkyl (C 5–12,14,15 )‐substituted 1,3′‐diazaflavanonium bromides 2a–j were prepared compound with corresponding alkyl halides in acetonitrile under reflux. In addition, nine , ′‐dialkyl 5–12,14 1,3′‐diazaflavonium 3a–i also synthesized using basic silica acetonitrile. The...
A simple and time-saving spectrofluorometric method developed using an azaflavanon-3-ol compound was used for the determination of iron in various food samples. Nitric acid hydrogen peroxide were digestion samples a closed microwave system. The validated by analyzing two certified reference materials (CRM-SA-C Sandy Soil C Mixed Polish Herbs INCT-MPH-2). Measurements carried out modified standard addition method. graph linear until 21.6 mg/L iron(III). Detection quantification limits 0.81...