A5045499577- Enzyme Structure and Function
- Genomics and Phylogenetic Studies
- Enzyme Production and Characterization
- Algal biology and biofuel production
- Cancer Research and Treatments
- Analog and Mixed-Signal Circuit Design
- Microbial Metabolism and Applications
- Microbial Community Ecology and Physiology
- Biochemical and Molecular Research
- Parasitic Infections and Diagnostics
- Molecular Sensors and Ion Detection
- Calcium Carbonate Crystallization and Inhibition
- Bacteriophages and microbial interactions
- Molecular Biology Techniques and Applications
- RNA modifications and cancer
- Infective Endocarditis Diagnosis and Management
- RNA and protein synthesis mechanisms
- Methane Hydrates and Related Phenomena
- Advancements in PLL and VCO Technologies
- VLSI and Analog Circuit Testing
- Microbial Applications in Construction Materials
- Software-Defined Networks and 5G
- Photosynthetic Processes and Mechanisms
- Machine Learning in Bioinformatics
- Marine Bivalve and Aquaculture Studies
Clemson University
2014-2024
Zhejiang University
2024
University of Georgia
2021-2024
Shenzhen Institutes of Advanced Technology
2022-2024
South China Normal University
2013-2024
Shenzhen University
2022
Sun Yat-sen University
2022
Southern Illinois University Carbondale
2007-2021
Hefei University of Technology
2021
Southwest University
2021
Efficient turn-on luminescent probes for <sc>l</sc>-cysteine sensing in serum are designed and synthesized based on an anionic Ln–K–MOF with tunable emission color heavy metal ion adsorption capacity.
Cryptosporidiosis is a leading cause of waterborne diarrheal disease globally and an important contributor to mortality in infants the immunosuppressed. Despite its importance, Cryptosporidium community has only had access good, but incomplete, parvum IOWA reference genome sequence. Incomplete sequences hamper annotation, experimental design, interpretation. We have generated new C. assembly supported by Pacific Biosciences (PacBio) Oxford Nanopore long-read technologies comparative...
Abstract Epialleles are meiotically heritable variations in expression states that independent from changes DNA sequence. Although they common plant genomes, their molecular origins unknown. Here we show, using mutant and experimental populations, epialleles Arabidopsis thaliana result ectopic hypermethylation due to feedback regulation of pathways primarily function maintain methylation at heterochromatin. Perturbations maintenance heterochromatin leads genes. Using single base resolution...
Abstract Once considered rare in eukaryotes, polycistronic mRNA expression has been identified kinetoplastids and, more recently, green algae, red and certain fungi. This study provides comprehensive evidence supporting the existence of apicomplexan parasite Cryptosporidium parvum . Leveraging long-read RNA-seq data from different strains using multiple technologies, we demonstrate defined transcripts containing 2-4 protein encoding genes, several validated with RT-PCR. Some polycistrons...
<title>Abstract</title> Duchenne and Becker muscular dystrophies (DMD/BMDs) are X-linked genetic disorders caused by mutations in the dystrophin gene (<italic>DMD</italic>), characterized progressive muscle weakness degeneration. While <italic>DMD</italic> duplications account for approximately 10% of cases, their clinical impact varies significantly, ranging from severe phenotypes to asymptomatic presentations, posing significant challenges determining pathogenicity. This study investigates...
The relationship between parasite genotype and pathogenesis is largely unknown for Cryptosporidium, a leading cause of diarrheal disease in children. An array parasites with similar genomes produces varied outcomes different hosts. Here, we isolate characterize Cryptosporidium parvum strains that show marked differences virulence persistence mice. Taking advantage the sexual lifecycle this eukaryotic pathogen, use genetic crosses to discover underlying chromosomal loci. Whole-genome...
ABSTRACT Cryptosporidium parvum is a significant pathogen causing gastrointestinal infections in humans and animals, that spread through the ingestion of contaminated food water. Despite its global impact on public health, generating C. genome sequence has always been challenging due to lack vitro cultivation systems sub-telomeric gene families. A gapless telomere assembly created for IOWA obtained from Bunch Grass Farms, named here as CpBGF. There are 8 chromosomes total 9,259,183 bp. The...
Time-frequency (TF) signal features are widely used in specific emitter identification (SEI) which commonly arises many applications, especially for radar signals. Due to data scale and algorithm complexity, it is difficult obtain an informative representation SEI with existing TF features. In this paper, a feature extraction method proposed based on synchrosqueezing transform (SST). The SST has equivalent dimension Fourier transform, retains the most relevant information of signal, leading...