A5043449377- Pharmacological Effects and Toxicity Studies
- Natural Antidiabetic Agents Studies
- Advanced Glycation End Products research
- Vanadium and Halogenation Chemistry
- Phytochemicals and Antioxidant Activities
- Biochemical effects in animals
- Vitamin C and Antioxidants Research
- Drug-Induced Hepatotoxicity and Protection
- Diet, Metabolism, and Disease
- Biochemical Acid Research Studies
- Trace Elements in Health
- Heavy Metal Exposure and Toxicity
- Free Radicals and Antioxidants
- Pregnancy and Medication Impact
- Moringa oleifera research and applications
- Pharmacological Effects of Natural Compounds
- Histone Deacetylase Inhibitors Research
- Metabolism, Diabetes, and Cancer
- Synthesis and biological activity
- Heme Oxygenase-1 and Carbon Monoxide
- Aluminum toxicity and tolerance in plants and animals
- Liver Disease Diagnosis and Treatment
- Phytochemistry and biological activity of medicinal plants
- Pancreatic function and diabetes
- Neurological Disorders and Treatments
Istanbul University-Cerrahpaşa
2019-2025
Istanbul University
2015-2024
Marmara University
1994-2022
National Institute of Technology Jamshedpur
2019
Quaid-i-Azam University
2019
Islamic Azad University, Lahijan Branch
2019
Maltepe University
2017
İstanbul Nişantaşı Üniversitesi
1998
Scientific and Technological Research Council of Turkey
1987
Moringa oleifera is a source of food, shelter and traditional medicine for many people in developing countries. It an exceptional vitamins, minerals, amino acids, lipids, carotenoids, flavonoids, sterols phenolics. Owing to its diverse nutritional phytochemical composition, it widely consumed used therapeutics. In this study, the aqueous, methanol, hexane ethyl acetate extracts M. seeds, leaves roots were assessed vitro α-amylase, α-glucosidase glucose-induced bovine serum albumin glycation...
The aim of this work was to investigate the effects Aloe vera leaf pulp and gel extracts on liver tissue neonatal streptozotocin (n0STZ)-induced type-II diabetic rats. rats were separated into four groups each group given following samples by gavage, daily for 15 d: phosphate buffered saline (PBS; control), extract, glibenclamide. Liver tissues examined histologically. markers oxidative stress: glutathione (GSH), non-enzymatic glycosylation (NEG) lipid peroxidation (LPO), determined in...
Metformin is a biguanide derivate used as an oral hypoglycaemic drug in diabetics. The aim of this study was to examine the histological and biochemical effects metformin streptozotocin (STZ)-treated rats. animals were rendered diabetic by intraperitoneal injection 65 mg/kg STZ. Fourteen days later, given at 25 gavage, daily for 28 days, STZdiabetic rats control group. In STZ-diabetic group, some degenerative changes observed light microscopic examination. But decreased group metformin....
Some series of arylidene barbiturates and thiobarbiturates were evaluated for their antibacterial, antioxidant, urease inhibition activities. The tested antimicrobial activity using the agar well diffusion technique against 13 bacteria. synthesized compounds (1a-g) screened antiurease antioxidant results showed that had effective antiurease, antibacterial
This study investigated both morphologically and biochemically whether parsley (Petroselinum crispum), which is used as a folk remedy to decrease blood glucose, has any antidiabetic effect on pancreatic B cells of rats. Parsley extract was given male diabetic In the group extract, it detected that number secretory granules in islets other morphologic changes were not different from control group, while glucose levels plant reduced comparison group. addition, observed weight extract. It...
In this study, the effect of combination vitamin C (ascorbic acid), E ( α-tocopherol), and selenium (sodium selenate) on ethanol-induced liver intestine injury in rats was investigated. The produced by administration 1 ml absolute ethanol to each rats. Animals received (250 mg/kg), sodium selenate (Se) (0.5 mg/kg) for 3 days; h after final antioxidant administration, they were sacrificed. Lipid peroxidation glutathione levels, catalase (CAT), lactate dehydrogenase (LDH), superoxide dismutase...
The aim of this study was to determine whether vitamin C, E, and selenium have protective effects against cadmium-induced renal toxicity rats. Vitamin C (250 mg/kg/day), E sodium selenate (0.25 mg/kg/day) were given rats orally for 8 days. Cadmium (2 mg/kg/day CdCl2) intraperitoneally. (in the same dose time) 1 h prior administration cadmium every day. tissue blood samples taken from histological evaluation biochemical analyses on Day 9. Lipid peroxidation (LPO) glutathione (GSH)...
ABSTRACT Pistacia atlantica Desf. (Anacardiaceae), a tree that is widely distributed in the Marmara, Mediterranean and Central Anatolia regions of Turkey, has been utilized traditionally for culinary medicinal purposes. In present study, methanolic ethyl acetate extracts were prepared from young leaves P. Desf., which collected during spring, their antioxidant, scavenging, chelating anti-acetylcholinesterase activities evaluated. Both showed strong antioxidant activity compared to synthetic...