- Neonatal Respiratory Health Research
- Renal and related cancers
- Respiratory Support and Mechanisms
- Airway Management and Intubation Techniques
- Sepsis Diagnosis and Treatment
- Chromosomal and Genetic Variations
- RNA modifications and cancer
- Circular RNAs in diseases
- Congenital Diaphragmatic Hernia Studies
- MicroRNA in disease regulation
- Tissue Engineering and Regenerative Medicine
- Genomics and Phylogenetic Studies
- Cardiac Arrest and Resuscitation
- CRISPR and Genetic Engineering
- Cancer-related molecular mechanisms research
Vall d'Hebron Hospital Universitari
2023-2024
Vall d'Hebron Institut de Recerca
2022
The Gurdon Institute
2016-2017
Wellcome Trust
2017
University of Cambridge
2016-2017
Universitat de Barcelona
2015-2016
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2015
The embryonic mouse lung is a widely used substitute for human development. For example, attempts to differentiate pluripotent stem cells epithelium rely on passing through progenitor states that have only been described in mouse. tip of the branching multipotent pool self-renews and produces differentiating descendants. We hypothesized distal an analogous population tested this by examining morphology, gene expression vitro self-renewal differentiation capacity tips. These experiments...
// Alfons Navarro 1 , Rut Tejero Nuria Viñolas 2 Anna Cordeiro Ramon M. Marrades 3 Dolors Fuster Oriol Caritg Jorge Moises Carmen Muñoz Laureano Molins 5 Josep Ramirez 4 Mariano Monzo Molecular Oncology and Embryology Laboratory, Human Anatomy Unit, School of Medicine, University Barcelona, IDIBAPS, Spain Department Medical Oncology, Institut Clinic Malalties Hemato-Oncològiques (ICMHO), Hospital de Pneumology, Clínic del Tórax (ICT), CIBER Enfermedades Respiratorias (CIBERES), Pathology,...
Abstract Background We aimed to assess the efficacy of a closed-loop oxygen control in critically ill patients with moderate severe acute hypoxemic respiratory failure (AHRF) treated high flow nasal (HFNO). Methods In this single-centre, single-blinded, randomized crossover study, adult AHRF who were HFNO (flow rate ≥ 40 L/min FiO 2 0.30) randomly assigned start 4-h period or manual titration, after which each patient was switched alternate therapy. The primary outcome percentage time spent...
The COVID-19 pandemic led to local oxygen shortages worldwide. To gain a better understanding of consumption with different respiratory supportive therapies, we conducted an international multicenter observational study determine the precise amount high-flow nasal (HFNO) and mechanical ventilation. A retrospective was in three intensive care units (ICUs) Netherlands Spain. Patients were classified as HFNO patients or ventilated patients, according mode supplementation which patient started....
<h3>Introduction and objectives</h3> Regeneration of healthy lung tissue in patients with end-stage respiratory disease (ESRD) would cure disease, rather than treating symptoms. For this a detailed understanding development is needed the mouse has been used extensively as an <i>in vivo</i> genetically-modifiable model. Differentiation validation human induced pluripotent stem cells (hiPSCs) entirely based on literature. The most important epithelial cell population developing lungs found...