A5022439793- Colorectal Cancer Screening and Detection
- Radiomics and Machine Learning in Medical Imaging
- Gastric Cancer Management and Outcomes
- Systemic Sclerosis and Related Diseases
- COVID-19 and healthcare impacts
- AI in cancer detection
- Colorectal Cancer Surgical Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Climate Change and Health Impacts
- COVID-19 diagnosis using AI
- Medical Imaging and Pathology Studies
- Liver Diseases and Immunity
- Dental Radiography and Imaging
- Healthcare cost, quality, practices
- Genetic factors in colorectal cancer
- Gallbladder and Bile Duct Disorders
- Dysphagia Assessment and Management
- Gastrointestinal Bleeding Diagnosis and Treatment
- Infection Control and Ventilation
- Colorectal and Anal Carcinomas
- Lung Cancer Diagnosis and Treatment
- Educator Training and Historical Pedagogy
- Inflammatory Bowel Disease
- Retinal Imaging and Analysis
- Digital Storytelling and Education
University of Oslo
2020-2025
Oslo University Hospital
2020-2025
Beth Israel Deaconess Medical Center
2021
Harvard University
2021
Vestre Viken Hospital Trust
2021
Artificial intelligence (AI) tools increase detection of precancerous polyps during colonoscopy and might contribute to long-term colorectal cancer prevention. The aim the study was investigate incremental effect implementation AI in screening on incidence mortality, cost-effectiveness such tools.We conducted Markov model microsimulation using with without for individuals at average risk (no personal or family history cancer, adenomas, inflammatory bowel disease, hereditary syndrome). We ran...
BACKGROUND: Artificial intelligence using computer-aided diagnosis (CADx) in real time with images acquired during colonoscopy may help colonoscopists distinguish between neoplastic polyps requiring removal and nonneoplastic not removal. In this study, we tested whether CADx analyzed helped decision-making process. METHODS: We performed a multicenter clinical study comparing novel CADx-system that uses real-time ultra-magnifying polyp visualization standard visual inspection of small (≤5 mm...
Background Computer-aided diagnosis (CADx) enables the distinction between neoplastic and non-neoplastic polyps during colonoscopy. We aimed to estimate patient-level benefit harm of CADx. Methods conducted a comparative analysis on data from EndoBRAIN international clinical trial, evaluating effect optical colonoscopy with without Three hypothetical scenarios were compared: “endoscopist-alone” “CADx-assisted” leave-in-situ strategies (leaving rectosigmoid ≤ 5 mm), “total removal” (removing...
Norway and Sweden are similar countries in terms of socioeconomics health care. implemented extensive COVID-19 measures, such as school closures lockdowns, whereas did not.
There is continued uncertainty regarding the risks of hepato-pancreato-biliary cancers in patients with inflammatory bowel disease (IBD) or without concomitant primary sclerosing cholangitis (PSC).To give updated estimates on risk IBD, including pancreatic cancer, hepatocellular carcinoma, gall bladder and intra - extrahepatic cholangiocarcinoma.In a population-based cohort study, we included all diagnosed IBD Norway Sweden from 1987 to 2016. The comprised 141,960 patients, identified...
Summary Background Women and men with colorectal adenomas are at increased risk of cancer colonoscopic surveillance is recommended. However, the long‐term remains unknown. Aims To investigate incidence mortality after adenoma removal in women Methods We identified all individuals who had removed Norway from 1993 to 2007, follow‐up through 2018. calculated standardized ratios (SIR) incidence‐based (SMR) 95% confidence intervals (CI) for using female male population comparison. defined...
Abstract Background Closed fitness centers during the Covid-19 pandemic may negatively impact health and wellbeing. We assessed whether training at increases risk of SARS-CoV-2 virus infection. Methods In a two-group parallel randomized controlled trial, center members aged 18 to 64 without Covid-19-relevant comorbidities, were access or no-access. Fitness applied physical distancing (1 m for floor exercise, 2 high-intensity classes) enhanced hand surface hygiene. Primary outcomes RNA status...
<h3>Background & Aims</h3> Because post-polypectomy surveillance uses a growing proportion of colonoscopy capacity, more targeted is warranted. We therefore compared burden and cancer detection using 3 different adenoma classification systems. <h3>Methods</h3> In case-cohort study among individuals who had adenomas removed between 1993 2007, we included 675 with colorectal (cases) diagnosed median 5.6 years after removal 906 randomly selected (subcohort). incidence high- low-risk defined...
Objectives Meticulous inspection of the mucosa during colonoscopy, represents a lengthier withdrawal time, but has been shown to increase adenoma detection rate (ADR). We investigated if artificial intelligence-aided speed monitoring can improve suboptimal time.Methods evaluated implementation computer-aided device colonoscopy at large academic endoscopy center. After informed consent, patients ≥18 years undergoing between 5 March and 29 April 2021 were examined without use speedometer, with...
Abstract Background Most countries closed training facilities during the COVID-19 pandemic. This may have negative consequences for people’s health and wellbeing. We investigated SARS-CoV-2 virus transmission disease attributable to facilities. Methods randomized members 18 64 years with no relevant comorbidities Five in Oslo, Norway access or their facility. Facilities were opened from May 22, 2020 individuals training, applying increased social distancing (1 meter floor exercise, 2 meters...
Abstract Objectives Norway and Sweden are similar countries regarding ethnicity, socioeconomics health care. To combat Covid-19, implemented extensive measures such as school closures lock-downs, while has been criticised for relaxed against Covid-19. We compared the effect of different national strategies on all-cause Covid-19 associated mortality. Design Retrospective cohort. Setting The Sweden. Participants All inhabitants. Main outcome calculated weekly mortality rates (MR) with 95%...
Artificial intelligence (AI) for polyp detection is being introduced to colonoscopy, but there uncertainty how this affects endoscopists' ability detect polyps and neoplasms. We performed a video-based study address whether AI improved the performance polyps.We established dataset of 200 colonoscopy videos (length 5 s; 100 without with one polyp). About 33 early-career endoscopists (50-400 colonoscopies performed) from 10 European countries classified each video as either 'polyp present' or...
<h3>Background</h3> Interstitial lung disease (ILD) progression can be assessed using different definitions. Declining forced vital capacity (FVC) is the simplest and most accepted. Both progressive pulmonary fibrosis (PPF) as defined by 2022 ATS/ERS/JRS/ALAT guideline, fibrosing ILD (PF-ILD) used in INBUILD, define a composite worsening of function, respiratory symptoms changes on high resolution chest tomography (HRCT), but with differences specific criteria. These new definitions have not...
Background Women are at high risk for painful colonoscopy. Pain, but also sedation, barriers to colorectal cancer (CRC) screening participation. In a randomised controlled trial, we compared on-demand with pre-colonoscopy opioid administration control pain in women CRC age.Methods Women, aged 55–79 years, attending colonoscopy two Norwegian endoscopy units were 1:1:1 (1) fentanyl on-demand, (2) prior colonoscopy, or (3) alfentanil on-demand. The primary endpoint was procedural reported by...
Aims Artificial intelligence with computer-aided diagnosis (CADx) enables real-time optical distinction between neoplastic versus nonneoplastic colon polyps during colonoscopy. We quantified healthcare costs, resource implications and patient burden associated the use of CADx in colonoscopy, utilizing data from a large clinical trial (EndoBRAIN International).
<h3>Background:</h3> Systemic sclerosis (SSc) is a multiorgan disease but, to date, only few definitions of the various organ manifestation specific for SSc exist. When available, these are mainly derived from other diseases, i.e. interstitial lung (ILD), where adopted idiopathic pulmonary fibrosis (IPF). For comparison clinical studies and inclusion patients in randomized trials, standardization involvement behaviour over time utmost importance. <h3>Objectives:</h3> To establish expert...
During the first wave of Covid-19 epidemic, a national lockdown was established in Norway, and inhabitants were asked to contact healthcare only if absolutely necessary. We investigated hospital admissions mortality due non-Covid-19 disease during compared previous years.We number emergency in-hospital fatality for diagnoses probably unaffected (acute myocardial infarction, acute abdominal conditions, cerebrovascular diseases) affected by (infections, injuries) South-Eastern Health Region...
Background: Based on the argument that symptoms define disease, physicians commonly apply terms “preclinical” or “subclinical” disease to describe patients with disease-related findings but no accompanying for connective tissue associated interstitial lung (CTD-ILD). The term subclinical frequently applies mild ILD changes high resolution chest tomography (HRCT), normal forced vital capacity (FVC), and without respiratory symptoms. Previous work in systemic sclerosis (SSc)-ILD did show even...