A5046527044- Crystallization and Solubility Studies
- Advanced biosensing and bioanalysis techniques
- X-ray Diffraction in Crystallography
- Electrochemical Analysis and Applications
- Biosensors and Analytical Detection
- Electrocatalysts for Energy Conversion
- Metal-Organic Frameworks: Synthesis and Applications
- Nanopore and Nanochannel Transport Studies
- Crystallography and molecular interactions
- Molecular Junctions and Nanostructures
- Luminescence Properties of Advanced Materials
- Microfluidic and Bio-sensing Technologies
- Atmospheric chemistry and aerosols
- Bacteriophages and microbial interactions
- Magnetism in coordination complexes
- Electrochemical sensors and biosensors
- Advanced battery technologies research
- Conducting polymers and applications
- Analytical Chemistry and Chromatography
- Luminescence and Fluorescent Materials
- Supercapacitor Materials and Fabrication
- DNA and Nucleic Acid Chemistry
- Marine and coastal ecosystems
- Optical properties and cooling technologies in crystalline materials
- CRISPR and Genetic Engineering
University of Otago
2024-2025
Australian Research Council
2020-2025
UNSW Sydney
2016-2025
East China University of Science and Technology
2020-2025
Xuchang University
2024
Ministry of Agriculture and Rural Affairs
2021-2023
Northwest A&F University
2021-2023
Jiangxi University of Science and Technology
2021-2022
Institute of Biophysics
2021
Chinese Academy of Sciences
2021
This Perspective focuses on the latest strategies and challenges for development of bioanalytical sensors with sub-picomolar detection limits. Achieving limits has three major challenges: (1) assay sensitivity, (2) response time, (3) selectivity (including limiting background signals). Each these is discussed, along how nanomaterials provide solutions. One strategy to gain greater sensitivity involves confining sensing volume nanoscale, as used in nanopore- or nanoparticle-based sensors,...
Abstract Nanopore sensors detect individual species passing through a nanoscale pore. This experimental paradigm suffers from long analysis times at low analyte concentration and non-specific signals in complex media. These limit effectiveness of nanopore for quantitative analysis. Here, we address these challenges using antibody-modified magnetic nanoparticles ((anti-PSA)-MNPs) that diffuse zero field to capture the analyte, prostate-specific antigen (PSA). The (anti-PSA)-MNPs are...
Realizing sensitive sub-tissue thermometry with a large signal-to-noise ratio <italic>via</italic> finely tailoring the local site symmetry in La<sub>2</sub>O<sub>3</sub>:Er<sup>3+</sup>/Yb<sup>3+</sup> nanospheres.
High sensitivity thermometer LuNbO<sub>4</sub>:Pr<sup>3+</sup>/Tb<sup>3+</sup> based on intervalence charge transfer transitions.
Self-monitored photothermal therapy (PTT) with minimal collateral damages has emerged as a challenging strategy for antibacterial and cancer treatments, which could be fulfilled via the rational integration of luminescent thermometry ablation within single upconverting (UC) nanoplatform. Herein, 808 nm light-driven dual-functional nanoplatforms LuVO4:Nd3+/Yb3+/Er3+@SiO2@Cu2S were successfully developed using olivelike LuVO4:Nd3+/Yb3+/Er3+ hollow nanoparticles thermal-sensing core ultrasmall...
This study introduces a new electrochemical sensing strategy for the rapid detection of circulating tumor DNA (ctDNA) from whole blood in combination with network DNA-Au@MNPs high sensitivity and excellent selectivity.
Enduring challenges for quantitative analysis in nanopore sensing are the detection of low biomarker concentrations reasonable time frames and multiple biomarkers same sample. Herein we report an optical blockade sensor strategy that can detect more than a protein at femtomolar rapid (approximately 12 min). This is done using array functionalized with aptamer bind to two different but related target proteins. The assay then monitors colors fluorescent particles modified antibodies specific...
The in situ tracking of the pyrolysis a binary molecular cluster [Zn7 (μ3 -CH3 O)6 (L)6 ][ZnLCl2 ]2 is presented with one brucite disk and two mononuclear fragments (L=mmimp: 2-methoxy-6-((methylimino)-methyl)phenolate) to porous carbon using TG-MS from 30 900 °C. Following up spilled gas product during decomposed reaction zinc along temperature rising, conjunction XRD, SEM, BET other materials characterization, where three key steps were observed: 1) cleavage bulky external ligand; 2)...
Lipid droplets (LDs) are critical for lipid storage and energy metabolism. LDs form in the endoplasmic reticulum (ER). However, molecular basis LD biogenesis remains elusive. Here, we show that fat storage–inducing transmembrane protein 2 (FIT2) interacts with ER tubule-forming proteins Rtn4 REEP5. The association is mainly domain based stimulated by oleic acid. Depletion of decreases number size cells Caenorhabditis elegans, mimicking loss FIT2. Through cytosolic loops, FIT2 binds to...
Impact experiments enable single particle analysis for many applications. However, the effect of trajectory a to an electrode on impact signals still requires further exploration. Here, we investigate measurements versus motion using micromotors with controllable vertical motion. With biocatalytic cascade reactions, micromotor system utilizes buoyancy as driving force, thus enabling more regulated interactions electrode. aid numerical simulations, dynamic between and are categorized into...
Mechanism of NIR <italic>PersL</italic> phosphor ZGSO:Yb<sup>3+</sup>,Er<sup>3+</sup>,Cr<sup>3+</sup> under the excitation 980 nm laser.
The conventional lateral flow immunoassay (LFIA) method using colloidal gold nanoparticles (Au NPs) as labeling agents faces two inherent limitations, including restricted sensitivity and poor quantitative capability, which impede early viral infection detection. Herein, we designed synthesized CsPbBr3 perovskite quantum dot-based composite nanoparticles, CsPbBr3@SiO2@Fe3O4 (CSF), integrated fluorescence detection magnetic enrichment properties into LFIA technology achieved rapid, sensitive,...