İsmail Demiryılmaz

ORCID: 0000-0003-4218-7558
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Research Areas
  • Organ Transplantation Techniques and Outcomes
  • Liver Disease and Transplantation
  • Liver Disease Diagnosis and Treatment
  • Alcoholism and Thiamine Deficiency
  • Esophageal and GI Pathology
  • Congenital Anomalies and Fetal Surgery
  • Renal and Vascular Pathologies
  • Organ Donation and Transplantation
  • Metabolism and Genetic Disorders
  • Pregnancy and Medication Impact
  • Transplantation: Methods and Outcomes
  • Vitamin C and Antioxidants Research
  • Gastrointestinal disorders and treatments
  • Gastroesophageal reflux and treatments
  • Gastrointestinal Tumor Research and Treatment
  • Abdominal Surgery and Complications
  • Clinical Nutrition and Gastroenterology
  • Renal Transplantation Outcomes and Treatments
  • Thyroid and Parathyroid Surgery
  • Thyroid Cancer Diagnosis and Treatment
  • Drug-Induced Hepatotoxicity and Protection
  • Paraoxonase enzyme and polymorphisms
  • Child Nutrition and Feeding Issues
  • Phytochemical and Pharmacological Studies
  • Methodologies in Health Research and Practice

Akdeniz University
2018-2023

Akdeniz University Hospital
2019-2021

Erzincan Binali Yıldırım University
2012-2018

Background:Oxidative liver injury occurring with methotrexate restricts its use in the desired dose. Therefore, whether or not thiamine and pyrophosphate, whose antioxidant activity is known, have protective effects on oxidative generated was comparatively researched rats using biochemical histopathological approaches.Material/Methods:Thiamine pyrophosphate+methotrexate, thiamine+methotrexate, were injected intraperitoneally for 7 days. After this period, all animals' livers excised, killing...

10.12659/msm.883591 article EN Medical Science Monitor 2012-01-01

The aim of this prospective study was therefore to evaluate the diagnostic value preoperative serum High Mobility Group Box Protein-1 (HMGB-1) levels in patients with Acute Appendicitis (AA) who show normal white blood cell count (WBC) counts. Our carried out from October 2010 through November and included 20 healthy control group participants 60 presented at emergency department Erzurum Training Research Hospital Turkey acute abdominal pain complaints, were pathologically diagnosed AA after...

10.1186/1757-7241-19-27 article EN cc-by Scandinavian Journal of Trauma Resuscitation and Emergency Medicine 2011-01-01

This study investigated the effect of thiamine pyrophosphate (TPP) on oxidative liver damage induced in rats with high-dose paracetamol.Rats for this experiment were divided into following groups: healthy control, paracetamol + paracetamol, TPP and N-acetylcysteine paracetamol. Oxidant antioxidant parameters function test levels compared between groups.The results show that equally prevented a rise oxidants such as malondialdehyde nitric oxide. They also decrease enzymatic nonenzymatic...

10.1016/j.jcma.2014.01.011 article EN publisher-specific-oa Journal of the Chinese Medical Association 2014-07-12

<b>Objectives:</b> The biochemical effects of thiamine pyrophosphate on ischemia-reperfusion (IR) induced oxidative damage and DNA mutation in rat kidney tissue were investigated, compared to thiamine.<br> <b>Materials Methods:</b> Rats divided into four groups: Renal (RIR); + RIR (TPRIR); (TRIR); sham group (SG).<br> <b>Results:</b> results experiments have shown that malondialdehyde (MDA) levels after TRIR TPRIR treatment 7.2 ± 0.5 (<i>P</i> > 0.05) 3.3 0.3 < 0.0001) μmol/g protein,...

10.4103/0253-7613.115005 article EN Indian Journal of Pharmacology 2013-01-01

Background:The burn wound represents a susceptible site for opportunistic colonization by organisms of endogenous and exogenous origin.Diminishing appetite is known to occur in patients with infection, yet its underlying reason not fully understood.We have examined the levels nesfatin 1, protein that we consider be potential new treatment target solution nutrition problem infection.Objectives: The aim present study was therefore examine infection.Material Methods: Laboratory values,...

10.5812/ircmj.4198 article EN cc-by-nc Iranian Red Crescent Medical Journal 2013-05-05

BACKGROUND:Dermatitis associated with ileostomy is an important problem that affects many people, especially children. The aim of this study was to investigate the therapeutic effects ozone on dermatitis due ileostomy, and develop alternative treatment option. MATERIAL AND METHODS:A total 28 rats were divided into 4 groups: control, ozone, zinc oxide. Ileostomy performed in all except control group. After a 1-week waiting time, group administered therapy oxide cream locally once day for 7...

10.12659/msm.897696 article EN Medical Science Monitor 2016-03-07

Perkütan endoskopik gastrostomi(PEG) ağız yoluyla beslenemeyen hastalara uzun dönem enteral beslenme sağlamak amacıyla karın duvarından mideye tüp yerleştirilmesidir.Bu çalışmamızda Genel cerrahi kliniğimizde PEG koyduğumuz hastaların endikasyonlarını, erken ve geç dönemde karşılaştığımız komplikasyonları sunmayı amaçladık.25 hastaya yerleştirildi.En sık konma nedeni 15 hasta ile (% 60) serebrovasküler hastalıklardı.18 evine taburcu edilirken, 7 hastanede izlemleri sırasında işlemine bağlı olmayan

10.5505/sakaryamj.2012.18480 article TR cc-by-nc-sa Sakarya Medical Journal 2012-01-01

In this study, effect of mirtazapine on gastric oxidative stress and DNA injury created with methotrexate was investigated.Experimental results showed that GSH (nmol/g protein), MDA (µmol/g protein) MPO (µ/g in the tissue control group rats receiving are 4.97 ± 0.37, 2.78 0.30 3.12 0.18, respectively.GSH, measurements + were detected to be 9.23 0.51(p < 0.0001), 1.80 0.31(p 0.0001) 1.63 0.25 (p values intact rat found 8 0.38 0,0001), 0.28 1.37 0.21 respectively.In addition, while 8-ohdG/dG...

10.14233/ajchem.2013.13296 article EN Asian Journal of Chemistry 2013-01-01

Echinococcus granulosus, ülkemizde sık görülen, genellikle karaciğerde gözlenen, paraziter bir hastalıktır. 20 yaşında erkek hasta, sağ ana hepatik kanala açılmış ve buna sekonder pankreas başında koledok dilatasyonuna sebep olan kist hidatik olgusu ile prezente edildi. Kolesistektomi, unroofing eksizyonu yapılan hasta postoperatif 3. gün taburcu Kontrol abdominal bilgisayarlı tomografi incelemesinde dilate görüntüsü kaybolan hastanın takiplerinde herhangi sorun karşılaşılmadı. Kist hidatik,...

10.31832/smj.376327 article TR cc-by-nc Sakarya Medical Journal 2018-03-26
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