A5087244548- Urological Disorders and Treatments
- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Urologic and reproductive health conditions
- Thyroid Cancer Diagnosis and Treatment
- Urinary Bladder and Prostate Research
- Gynecological conditions and treatments
- Genital Health and Disease
- Ureteral procedures and complications
- Pediatric Urology and Nephrology Studies
- Epigenetics and DNA Methylation
- Prostate Cancer Diagnosis and Treatment
- Cardiovascular Disease and Adiposity
- Viral-associated cancers and disorders
- Pelvic floor disorders treatments
- Sexual Differentiation and Disorders
- Renal cell carcinoma treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Cancer, Lipids, and Metabolism
- Testicular diseases and treatments
- Systemic Sclerosis and Related Diseases
- Adrenal and Paraganglionic Tumors
- Veterinary Medicine and Surgery
- Diphtheria, Corynebacterium, and Tetanus
- Poisoning and overdose treatments
National Institute of Emergency Medicine "Pirogov"
2015-2025
Evidence-practice gaps exist in urology. We previously surveyed European Association of Urology (EAU) guidelines for strong recommendations underpinned by high-certainty evidence that impact patient experience which practice variations were suspected. The recommendation "Do not offer neoadjuvant androgen deprivation therapy (ADT) before surgery patients with prostate cancer" was prioritised further investigation. ADT is neither clinically effective nor cost and has serious side effects....
The aims of the current study are estimation correlations between oxidative stress and neuroregenerative processes new pharmacotherapeutic approaches in treatment Parkinsonism. investigation has been made through existing electronical database medical sources. Oxidative arises from an increased production reactive oxygen/nitrogen species (ROS/RNS) or a failure body’s antioxidant defenses, characterized by reduced ability endogenous systems to combat attack directed at target biomolecules. It...
Visible hematuria is not rare in patients on anticoagulant therapy. There no consensus regarding the diagnostic approach for them; some authors suggest restricted volume of procedures because low number urological etiology found. Some antibiotics have been reported to potentiate effect oral anticoagulants.The study addresses need assessment anticoagulation therapy and possible role drugs administrated simultaneously with an anticoagulant, onset macroscopic hematuria. Patients hospitalized...
To evaluate the efficacy and safety of UGN-102 chemoablation for primary treatment patients with recurrent low-grade intermediate-risk nonmuscle-invasive bladder cancer.
The aim of the present study was to detect copy number variations (CNVs) related tumour progression and metastasis urothelial carcinoma through whole-genome scanning. A total 30 bladder cancer samples staged from pTa pT4 were included in study. DNA extracted freshly frozen tissue via standard phenol-chloroform extraction CNV analysis performed on two alternative platforms (CytoChip Oligo aCGH, 4x44K Infinium OncoArray-500K BeadChip; Illumina, Inc.). Data analysed with BlueFuse Multi software...
Congenital adrenal hyperplasia (CAH) patients with testicular rest tumors (TARTs) enlargement present a serious diagnostic challenge. According to the data TARTs are usually benign. They rare, resulting in paucity medical literature regarding their pathological features. We report case of bilateral synchronous mass-forming marked cytological and nuclear atypia misinterpreted as malignant 40-years-old man CAH CT MRI for pheochromocytoma right gland paraaortal paracaval lymphadenomegaly. He...
Many bladder cancer (BC) patients with early disease are asymptomatic and diagnosed at advanced stage when the therapeutic options limited. This necessitates development of reliable predictive molecular biomarkers that will ensure a positive response in every patient. The aim this study was to screen for alterations gene expression levels related drug sensitivity resistance may be further explored as potential biomarkers. Gene analysis 168 genes from two panels Cancer metabolism (PAHS004)...
Congenital diverticulum is a very rare disease of the urethra in which there sacculus enlargement on its ventral surface. We present Case 2-year-old boy with symptoms urinary hesitancy and swelling penoscrotal angle that appears during micturition. The diagnosis urethral confirmed by retrograde urethrography voiding cystogram. An open operation was performed - diverticulectomy primary repair urethra.
Hydatid disease is a condition affecting mainly the liver or, to lesser extent, lungs. We present an uncommon case of primary renal echinococcosis in young man complaining intermittent hematuria, dull flank pain, and palpable mass left lumbar lateral abdominal area which increases its size over time. After initial self-treatment with painkillers antibiotics, patient was referred urological clinic, where physical examination revealed large tumour kidney. Ultrasound showed multilocular cyst,...
Fetal urinomas are often diagnosed in prenatal ultrasonography. The etiology is usually an obstructive uropathy leading to hydronephrosis and increased intrarenal pressure putting future kidney function at risk. Rupture of pyelocaliceal system such cases may lead retroperitoneal urinoma or urinary ascites, sepsis, uraemia, acute renal failure. On the other hand, this serve as “pop-off valve” mechanism decreasing protecting from definitive loss. We present a case newborn girl with urinoma,...
Pediatric urolithiasis is a very specific and challenging problem in the field of modern urology. Currently, there are three major methods for kidney stone removal: extracorporeal shock wave lithotripsy (ESWL), retrograde intrarenal surgery (RIRS), percutaneous nephrolithotomy (PCNL), latter one proving to be an efficient safe monotherapy stones even with larger burden. Different sizes nephroscopes used (standard, mini, micro), where smaller size logically correlated safer profile,...
Surgical treatment of urethral strictures is a constantly evolving process. There are various options like internal urethrotomy (IUT) and open surgery. A variety techniques for reconstruction available (grafts, flaps, excision-reanastomosis). Functional results reconstructive surgery very satisfying with low rate complications.We assessed the early surgical in comparison continuation endourological - IUTs.The study included 129 patients referred to our center. At that time point, they had...
A case of occult carcinoma the ureteral stump is reported. 67-year-old man presented with pain syndrome due to multiple bone metastases from unknown primary origin detected by previous imaging studies as magnetic resonance imaging, whole body contrast-enhanced computed tomography (CT), and technetium-99m methyldiphosphonate scan. He had undergone a right nephrectomy for benign disease previously. was referred our department an 18F-fluoro-2-deoxy-D-glucose (18F-FDG) positron emission...
You have accessJournal of UrologyPenis/Testis/Urethra: Benign & Malignant Disease (II)1 Apr 2013761 SURGICAL MANAGEMENT OF URETHRAL STRICTURE DISEASE AFTER 2-ND FAILED INTERNAL URETHROTOMY (IUT) COMPARED TO CONSECUTIVE IUT- SINGLE CENTER EXPERIENCE Valeri Mariyanovski, Stoyan Peev, Boris Mladenov, and Galia Muzikadzieva MariyanovskiValeri Mariyanovski Sofia, Bulgaria More articles by this author , PeevStoyan Peev MladenovBoris Mladenov MuzikadzievaGalia View All Author...
Bladder cancer holds a steady 10th place among oncological diseases. Follow-up and timely diagnosis of recurrence progression bladder are still based on regular but outdated cystoscopy followed by cytological examination. To reduce the number procedures, new reliable biomarkers for predicting tumor behavior must be developed. The aim this study was to confirm our previous results that demonstrated overexpression AP1S1, CDK9, FIGF HDAC11 in muscle-invasive cancer. project management performed...
Етиологията, патогенезата и лечението на злокачествените новообразувания пикочния мехур все още пораждат редица въпроси. Установени са биомаркери, показващи разлики в молекулния образ инвазивния неинвазивния уроепителен карцином, които част от факторите, отговорни за големите вариации дори при тумори с еднакъв хистологичен резултат. В момента стандартно прилаганата системна терапия включва различни цитотоксични химиотерапевтични схеми се основава главно хистологичната оценка стадирането...
Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a rare congenital disorder affecting female reproductive system (agenesis of uterus and upper part vagina) alone (type 1), or associated with abnormalities other organs systems 2). We report case 21-year-old woman diagnosed MRKH due to primary amenorrhea during puberty operated for formation neovagina. She was admitted the Department Urology abdominal pain oligoanuria, where physical examination imaging studies revealed malformation...