A5037798333- Animal Ecology and Behavior Studies
- Genetics and Physical Performance
- Bat Biology and Ecology Studies
- Animal Behavior and Reproduction
- Genetic diversity and population structure
- Insect and Pesticide Research
- Physiological and biochemical adaptations
- Congenital limb and hand anomalies
- Genetic Mapping and Diversity in Plants and Animals
- Cryospheric studies and observations
- High Altitude and Hypoxia
- dental development and anomalies
- Genomics and Chromatin Dynamics
- Identification and Quantification in Food
- Congenital heart defects research
- Periodontal Regeneration and Treatments
- New Zealand Economic and Social Studies
- Adipose Tissue and Metabolism
- Marine animal studies overview
- Developmental Biology and Gene Regulation
- Folklore, Mythology, and Literature Studies
- Bone and Dental Protein Studies
- Evolution and Paleontology Studies
- Cephalopods and Marine Biology
- Pluripotent Stem Cells Research
University of Wisconsin–Madison
2020-2025
The University of Texas MD Anderson Cancer Center
2008-2014
Zero to Three
2008-2009
Brigham Young University
2007
Abstract Population structuring in species inhabiting marine environments such as the Northeast Atlantic Ocean (NEA) and Mediterranean Sea (MS) has usually been explained based on past present physical barriers to gene flow isolation by distance (IBD). Here, we examined relative importance of these factors population common cuttlefish Sepia officinalis using methods phylogenetic inference hypothesis testing coupled with coalescent classical genetic parameter estimation. Individuals from 10...
Island populations are hallmarks of extreme phenotypic evolution. Radical changes in resource availability and predation risk accompanying island colonization drive behavior, which Darwin likened to tameness domesticated animals. Although many examples animal boldness found on islands, the heritability observed behaviors, a requirement for evolution, remains largely unknown. To fill this gap, we profiled anxiety exploration mainland inbred strains house mice raised common laboratory...
Abstract Organismal body weight correlates with morphology, life history, physiology, and behavior, making it perhaps the most telling single indicator of an organism’s evolutionary ecological profile. Island populations provide exceptional opportunity to study evolution. In accord “island rule,” insular small-bodied vertebrates often evolve larger sizes, whereas large-bodied smaller sizes. To understand how island extreme we adopted a developmental perspective compared suite traits...
Abstract An embryonic staging system for Molossus rufus (also widely known as ater ) was devised using 17 reference specimens obtained during the postimplantation period of pregnancy from wild‐caught, captive‐bred females. This done in part by comparing embryos to a developmental that had been created another, relatively unrelated bat, Carollia perspicillata (family Phyllostomidae). Particular attention paid development species‐specific features, such wing and ear morphology, these are...
Abstract Organismal body weight correlates with morphology, life history, physiology, and behavior, making it perhaps the most telling single indicator of an organism’s evolutionary ecological profile. Island populations provide exceptional opportunity to study evolution. In accord “island rule,” insular small-bodied vertebrates often evolve larger sizes, whereas large-bodied smaller sizes. To understand how island extreme we adopted a developmental perspective compared suite traits...
SUMMARY Transcriptional enhancers are genomic sequences bound by transcription factors that act together with basal transcriptional machinery to regulate gene transcription. Several high‐throughput methods have generated large datasets of tissue‐specific enhancer putative roles in developmental processes. However, few been deleted from the genome determine their development. To understand two active mouse embryonic limb bud we them genome. Although genes regulated these unknown, they were...
The Transforming growth factor β (Tgf-β) pathway, by signaling via the activation of Smad transcription factors, induces expression many diverse downstream target genes thereby regulating a vast array cellular events essential for proper development and homeostasis. In order specific cell type to properly interpret Tgf-β signal elicit response, cell-specific transcriptional co-factors often cooperate with Smads activate discrete set in appropriate temporal spatial manner. Here, conditional...
The evolution of behaviour on islands is a pervasive phenomenon that contributed to Darwin's theory natural selection. Island populations frequently show increased boldness and exploration compared with their mainland counterparts. Despite the generality this pattern, genetic basis island-associated behaviours remains mystery. To address gap in knowledge, we genetically dissected 613 F2s generated by crossing inbred mouse strains from Gough (where they live without predators or human...
Abstract Island populations repeatedly evolve extreme body sizes, but the genomic basis of this pattern remains largely unknown. To understand how organisms on islands gigantism, we compared genome-wide patterns gene expression in Gough mice, largest wild house mice world, and mainland from WSB/EiJ wild-derived inbred strain. We used RNA-seq to quantify differential three key metabolic organs: gonadal adipose depot, hypothalamus, liver. Between 4,000 8,800 genes were significantly...
Abstract The helmeted appearance of the black mastiff bat, Molossus rufus , at embryonic stage 21 results from anterior margins ears being progressively situated near facial midline during development. Comparative bat embryology provides a foundation for understanding unique mammalian and chiropteran (bat) adaptations, such as marked ability M. to use its compactly folded wings terrestrial quadrupedal locomotion. See Nolte et al., on page 155, in this issue.
Abstract Island populations are hallmarks of extreme phenotypic evolution. Radical changes in resource availability and predation risk accompanying island colonization drive behavior, which Darwin likened to tameness domesticated animals. Although many examples animal boldness found on islands, the heritability observed behaviors, a requirement for evolution, remains largely unknown. To fill this gap, we profiled anxiety exploration mainland inbred strains house mice raised common laboratory...