- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Valve Diseases and Treatments
- Cardiovascular Disease and Adiposity
- Cardiac and Coronary Surgery Techniques
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Health and Mental Health
- Aortic aneurysm repair treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Vascular Procedures and Complications
- Healthcare Regulation
- COVID-19 and healthcare impacts
- Medical Image Segmentation Techniques
- Healthcare during COVID-19 Pandemic
- Cardiac pacing and defibrillation studies
- Advanced MRI Techniques and Applications
- AI in cancer detection
- Advanced X-ray and CT Imaging
- Infective Endocarditis Diagnosis and Management
- COVID-19 and Mental Health
- Cardiovascular Issues in Pregnancy
- Peripheral Artery Disease Management
- COVID-19 Clinical Research Studies
Hospital de Messejana
2018-2025
Sociedade Brasileira de Cardiologia
2023
National Heart Institute
2020
Universidade Federal do Ceará
2018-2019
Associação Fundo de Incentivo à Pesquisa
2019
Universidade de São Paulo
2007-2018
Hospital Sírio-Libanês
2015-2018
Hospital São Paulo
2018
Universidade Estadual do Ceará
2018
Massachusetts Institute of Technology
2015
Oral mucositis is a frequent side‐effect of cancer therapy. A definitive method prophylaxis or treatment not yet available. As pentoxifylline (PTX) and thalidomide (TLD) have been shown to inhibit cytokine synthesis, we studied the effects these inhibitors in an experimental oral model. was induced Golden hamsters by administration 5‐fluorouracil (5‐FU) followed mechanical trauma cheek pouch. On days 4, 5, 10, 12, 14 16, lesions 5‐FU were examined macroscopically microscopically, presence...
The aim of this study is to present a new methodology for three-dimensional (3D) reconstruction coronary arteries and plaque morphology using Computed Tomography Angiography (CTA). summarized in six stages: 1) pre-processing the initial raw images, 2) rough estimation lumen outer vessel wall borders approximation vessel's centerline, 3) manual adaptation parameters, 4) accurate extraction luminal 5) detection - calcium region, 6) finally 3D surface construction. was compared estimations...
Abstract Objectives To report clinical, angiographic characteristics, outcomes, and predictors of unsuccessful procedures in patients who underwent chronic total occlusion (CTO) percutaneous coronary interventions (PCI) Latin America. Background CTO PCI has been increasingly performed worldwide, but there is a lack information this region. Methods An international multicenter registry was developed to collect data on centers Patient, angiographic, procedural outcome were evaluated....
We aimed to evaluate if the co-localisation of calcium and necrosis in intravascular ultrasound virtual histology (IVUS-VH) is due artefact, whether this effect can be mathematically estimated.We hypothesised that, case induces an artefactual coding necrosis, any addition content would generate artificial increment necrotic tissue. Stent struts were used simulate "added calcium". The change amount spatial localisation tissue was evaluated before after stenting (n=17 coronary lesions) by...
To evaluate the diagnostic performance of a novel computational algorithm based on three-dimensional intravascular ultrasound (IVUS) imaging in estimating fractional flow reserve (IVUSFR ), compared to gold-standard invasive measurements (FFRINVAS ).IVUS provides accurate anatomical evaluation lumen and vessel wall has been validated as useful tool guide percutaneous coronary intervention. However, IVUS poorly represents functional status (i.e., flow-related information) imaged...
Background Bioprosthetic mitral valve degeneration can be problematic as redo surgical replacement (Redo-SMVR) is associated with a high morbidity and mortality. Valve-in-valve transcatheter (TMVR) has emerged an alternative for high-risk patients, but comparative data lacking. Objectives We aimed to evaluate the outcomes of Redo-SMVR vs. TMVR, using either transapical (TA) or transseptal (TS) approach. Methods Results A total 415 patients (69% rheumatic) were included between January 2014...
Abstract Objectives We aimed to explore angiographic patterns and in‐hospital outcomes of patients with concomitant coronavirus disease‐19 (COVID‐19) myocardial infarction (MI). Background Patients COVID‐19 may experience MI during the course viral infection. However, this association is currently poorly understood. Methods This a multicenter prospective study consecutive who underwent coronary angiography. Quantitative qualitative angiography were analyzed by two observers in an independent...
To utilize telemedicine as a foundation platform for creating population-based STEMI networks.Disparate acute myocardial infarction (AMI) management occurs in developed and developing countries on account of differences infrastructure resources. As result, primary percutaneous coronary intervention (PCI) second- third-generation thrombolytic therapy, contrast to countries, which primarily rely earlier-generation therapy basic medical management. Reducing the vast gap AMI care between is an...
Background: The use of aortic counterpulsation therapy in advanced heart failure is controversial.Objectives: To evaluate the hemodynamic and metabolic effects intra-aortic balloon pump (IABP) its impact on 30-day mortality patients with failure.Methods: Historical prospective, unicentric study to all treated IABP betwen August/2008 July/2013, included an institutional registry named TBRIDGE (The Brazilian Registry Intra-aortic Decompensated -Global Evaluation).We analyzed changes oxygen...
The present study aimed to evaluate the clinical performance, in daily practice of a busy catheterization laboratory, novel drug-eluting stent (DES) built with an ultra-thin-strut metallic platform, eluting sirolimus at low doses, abluminal coated biodegradable polymers, and mounted low-compliant delivery system.Prospective, single-arm study, comprising all consecutive patients undergoing percutaneous coronary intervention (PCI) Inspiron™ sirolimus-eluting (SES) (Scitech, Aparecida de...
dos infectados tem apresentações clínicas brandas.
Background: The diagnostic accuracy of 64-slice MDCT in comparison with IVUS has been poorly described and is mainly restricted to reports analyzing segments documented atherosclerotic plaques.Objectives: We compared multidetector computed tomography (MDCT) gray scale intravascular ultrasound (IVUS) for the evaluation coronary lumen dimensions context a comprehensive analysis, including absent or mild disease.Methods: was performed within 72 h before imaging, which obtained at least one...
Virtual Histology (VH) is a new medical imaging technique that allows the assessment of atherosclerotic plaque composition, potential useful tool for evaluation individuals with coronary disease. Empirical observation has suggested areas adjacent to dense calcium (DC) are frequently coded as necrotic core (NC) in VH images. The main objective study was evaluate whether presence DC induces an artifactual coding NC structures. To test this effect, set 89 arteries segments have been analyzed...
Background Social isolation and marketing campaign to avoid "unnecessary" use of healthcare system fight against COVID-19 pandemic might impact on the decision seek medical care. The aim this study was evaluate effect social during trends in numbers visits emergency department, non-elective admissions, percutaneous coronary intervention procedures for treatment patients with acute myocardial infarction, at a reference cardiology hospital. Methods Daily [...]
Geralmente, a cardiomiopatia restritiva por deposição de desmina é caracterizada pela restrição ao enchimento diastólico ventricular e diferentes graus bloqueio atrioventricular (BAV). Neste relato, são descritas as alterações anatomopatológicas do sistema condução cardíaco relacionadas BAV. O nó sinusal, o compacto feixe penetrante (feixe His) não apresentavam anormalidades, entretanto, havia extensa fibrose das porções terminais ramificante início dos feixes esquerdo direito, no topo septo...
Aware of the new evidence and lessons on progress novel coronavirus pandemic (COVID-19) in Brazil all over world, its impact routine Interventional Cardiology, we have updated positioning Sociedade Brasileira de Hemodinâmica e Cardiologia Intervencionista to reinforce practical orientations detail some specific aspects related protection healthcare workers indication procedures cath lab. Update SBHCI about COVID-19
Coronary three-dimensional reconstruction with the combination of intravascular ultrasound and angiography offers advantages over computed tomography coronary arteries. The authors aimed to present pilot phase validation a new model This study used examinations already performed by clinical indication in individuals known or suspected stable artery disease. Image processing, segmentation, were conducted following specific methodology. For geometrical characterization purposes, tridimensional...