Mariana Nepomuceno

ORCID: 0000-0003-4231-9215
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About
Contact & Profiles
Research Areas
  • Alzheimer's disease research and treatments
  • Diet and metabolism studies
  • Dementia and Cognitive Impairment Research
  • Sleep and Wakefulness Research
  • Vitamin C and Antioxidants Research
  • Sleep and related disorders
  • Trypanosoma species research and implications
  • Biochemical effects in animals
  • Research on Leishmaniasis Studies
  • Circadian rhythm and melatonin

Universitat de València
2019-2024

Centro de Investigación Biomédica en Red
2024

INCLIVA Health Research Institute
2019-2020

Estácio (Brazil)
2012

Universidade do Estado do Rio de Janeiro
2012

Carrying an allele 4 of the apolipoprotein E (ApoE) is best-established genetic risk factor to develop Alzheimer's disease (AD). Fifty percent ApoE4/4 individuals at 70 years age. ApoE3/4 carriers have a lower developing disease, still 50% them suffer AD around 80 years. In previous study we showed that healthy young individuals, who had parent with and were least one ApoE4 displayed reductive stress. This was evidenced as decrease in oxidative markers, such oxidized glutathione, p-p38, NADP

10.1016/j.freeradbiomed.2024.02.021 article EN cc-by-nc-nd Free Radical Biology and Medicine 2024-02-27

Summary For better efficiency in the establishment of American tegumentary leishmaniasis clinical cure, World Health Organization suggests that criteria are supported by serologic data. The present study aims to investigate dynamics IgG subclass production evolution post‐treatment cutaneous (CL). Paired sera from 23 subjects with CL resulting Leishmania braziliensis infection were studied during active lesion phase (aCL) and after cure post‐therapy (hCL), which included an alternative...

10.1111/j.1365-3024.2012.01379.x article EN Parasite Immunology 2012-06-28

(Appeared originally in Int J Mol Sci 2019, 20 5536).

10.1176/appi.focus.19305 article EN FOCUS The Journal of Lifelong Learning in Psychiatry 2021-07-01
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