Introduction: Hydatid disease, caused by Echinococcus granulosus , commonly affects the liver (80%) and lungs (15%). Muscular involvement is rare, with primary hydatid cysts in skeletal muscles comprising only 2–3% of cases. This report presents first documented case a cyst rectus abdominis muscle Nepal, 11th globally. Case presentation: A 38-year-old female presented progressively enlarging epigastric swelling localized pain over 1 year. On examination, firm, non-tender 5 × cm mass was...

Solvent abuse, as inhalant specially, in the form of low cost adhesives like dendrite is common income countries among children and teens. This habit often a stepping stone to harder drugs. The neurological neuropsychological effects solvent abuse are well explored. But respiratory overlooked. In this report, we present case 19 year old gentleman, with regular history sniffing commercial “glue” compounds. patient presented right sided chest pain x-ray showed pneumothorax. pulmonary...

Pleurodesis is a procedure to achieve symphysis between the two layers of pleura aimed at preventing accumulation either air or fluid in pleural space. In Nepal, intrapleural instillation chemical sclerosing agent more commonly done as thoracoscopy facility not easily available. However, iodopovidone rarely used for this purpose Nepal. The study aims find prevalence success using agent.The included cases undergoing pleurodesis over two-year period. clinicodemographic data, diagnosis,...

Background: Paragonimiasis presents with nonspecific symptoms and radiologic findings, allowing for the possibility of misdiagnosis. Diagnosis is generally delayed due to lack suspicion presentation similar pulmonary tuberculosis. Methods: A prospective observational study was carried out on 20 subjects at Civil Service Hospital Nepal from March 2015 June 2019 who presented eosinophilia symptoms, were treated empirically Anti-tubercular therapy Results: The median age patient 34 years. Mean...

Background and Objectives: Carbon Monoxide (CO) poisoning is a leading cause of injury death due to in many parts the world. Among numerous sources CO, gas water heater can be potential under looked source causing an accidental monoxide poisoning. In perspective Kathmandu valley, where there are houses with small bathrooms, inadequate ventilation absent CO detectors, heaters extremely dangerous even if it liberates amount gas. Herein, we present case increase awareness about use possible...

Background : Many patients attending routine respiratory clinical service in developing countries also present with complains of daytime sleepiness and sleep abnormalities. A large proportion them might have Sleep Related Breathing Disorders (SRBD) as such, it is underestimated. Within this background we conducted a study to explore the presence SRBD among presenting symptom complex diseases Routine Respiratory Clinical Service by use Epworth Sleepiness Scale (ESS).Material Methods:...

Introduction: The burden of Overlap Syndrome (coexistence sleep-related breathing disorders in patients with respiratory diseases) is high developing countries, and such a phenomenon implies higher morbidity. study was conducted to measure the prevalence Respiratory Symptom Complex identify factors associated severity disorders.Materials Methods: A hospital-based cross-sectional 50 symptom complex at BP Koirala Institute Health Sciences. Structured proforma Polysomnography were used for...

Background Spontaneous pneumothorax is not an uncommon medical emergency in pulmonary practice. Related data are available our setting. In departments, clinical presentation often confused with other cardiopulmonary problems. Follow up outcome important for better patient care.
 Objective To study profile and after non surgical intervention a tertiary care center.
 Method This was prospective observational carried out Nobel Medical College, Biratnagar over last 3 years. We enrolled...

Severe coronavirus disease 2019 can be associated with progressive respiratory failure. In addition to support and other supportive care, use of corticosteroids has shown improve outcome. Despite the steroids, a significant proportion patients progressively worsen. Adjunct immunomodulators have been studied in steroids these patients. Here we present successful tofacitinib, Janus Kinase inhibitor, conjunction dexamethasone for patient rapid worsening status high level serum inflammatory biomarkers.

Introduction: In the background of resource limited setting like Nepal, we set out to identify if specific clinical characteristics and basic lab parameters would guide differentiation Tuberculous from other causes exudative pleural effusion.Methodology: Retrospective study 109 consecutive patients with effusion.Results: Compared Tubercular effusions (41.3%), increased age, duration symptom pack years statistically favoured a diagnosis Malignant effusion(21.1%), whereas presence fever, cough...

Introduction: The management of Empyema Thoracis is challenging. It requires specialist medical and surgical care at the same time. There are lack data regarding clinical profile steps day to management, hence this study aims identify these parameters focus on gaps in that commonplace our setting representative other resource limited settings as well.
 Methods: Clinical profile, etiological agents, hospital course outcome 30 patients with empyema thoracis treated from 2012 2014 B.P....

investigated the role of on an model Ovalbumin (OVA) -sensitized and challenged allergic airway inflammation in both BALB/c C57BL/6 mice.Nrf2-/-and Nrf2+/+ mice were used mice.Allergic was generated by intraperitoneal sensitization with OVA/alum days 0, 6 7.The OVA intranasally day 21.After challenge twentyfour hours, we examined cell populations inflammatory cytokines bronchoalveolar lavage (BAL) fluid, IgE levels serum.The number neutrophils BAL fluid serum significantly increased...

investigated the role of on an model Ovalbumin (OVA) -sensitized and challenged allergic airway inflammation in both BALB/c C57BL/6 mice.Nrf2-/-and Nrf2+/+ mice were used mice.Allergic was generated by intraperitoneal sensitization with OVA/alum days 0, 6 7.The OVA intranasally day 21.After challenge twentyfour hours, we examined cell populations inflammatory cytokines bronchoalveolar lavage (BAL) fluid, IgE levels serum.The number neutrophils BAL fluid serum significantly increased...

Introduction: Critical Care management is an important issue in developing countries where Medical Intensive Units (MICU) patients have comorbidity or complications of multisystem involvement.
 Objectives: The objective study was to analyze clinical profiles Unit and identify applicable factors that prognosticate outcomes.
 Methodology: Study conducted at B. P. Koirala Institute Health Sciences, Dharan, Nepal. Records from July 31, 2013 August 1, 2014 were retrospectively studied....

Spontaneous pneumomediastinum is rare condition with free air in the mediastinum. There are some controversies to consider spontaneous patients predisposing factors like asthma, interstitial lung disease, illicit drug users and irritant inhalations. It generally occurs due sudden increase intrathoracic pressure causing rupture of alveoli movement Here we present a case 20 years old male patient few bouts cough as precipitating factor development subcutaneous emphysema.

Introduction: Hemoptysis is a common but distressing and alarming symptom in patient. Data related to detail clinical profile follow up study of hemoptysis are lacking.
 Objective: This was carried out see the patients with recurrences tertiary care centre province 1 within period.
 Methodology: prospective observational conducted at department Pulmonary, Critical Care Sleep Medicine Nobel Medical College Teaching Hospital, Biratnagar, Nepal. The between 30th January 2017 1st...

Background: Early diagnosis of pulmonary tuberculosis is difficult but dreaded complications like cavitations, abscess, disseminations and fibrosis lung parenchyma can be avoided. Sputum microscopy still the most available test for sustainable number active cases remains undiagnosed via this method alone. In strong clinico-radiological patients who are sputum scarce or Xpert MTB/Rif negative broncho-alveolar lavage may provide superior sample Gene in Pulmonary Tuberculosis.
 Materials...

Co-infection of COVID-19 with dengue infection is quite challenging to differentiate due it’s overlapping clinical and laboratory manifestations. We report a 22-year-old female presented Civil Service Hospital, emergency department complaints persistent fever multiple episodes vomiting, headache myalgia. On examination, she was ill-looking, dehydrated low blood. Reverse transcriptase – polymerase chain reaction nasopharyngeal swab detected SARS CoV-2, antibodies IgM detected. She...