A5089895351- Stroke Rehabilitation and Recovery
- Acute Ischemic Stroke Management
- Cerebral Palsy and Movement Disorders
- Motor Control and Adaptation
- Cerebrovascular and Carotid Artery Diseases
- Advanced Neuroimaging Techniques and Applications
- Botulinum Toxin and Related Neurological Disorders
- Transcranial Magnetic Stimulation Studies
- Muscle activation and electromyography studies
- Musculoskeletal pain and rehabilitation
- Spatial Neglect and Hemispheric Dysfunction
- Sport Psychology and Performance
- Spinal Cord Injury Research
- Laser Applications in Dentistry and Medicine
- Meta-analysis and systematic reviews
- Balance, Gait, and Falls Prevention
- EEG and Brain-Computer Interfaces
- Dementia and Cognitive Impairment Research
- Migraine and Headache Studies
- Hemispheric Asymmetry in Neuroscience
- Health Systems, Economic Evaluations, Quality of Life
- Neural and Behavioral Psychology Studies
- Dental Anxiety and Anesthesia Techniques
SUNY Upstate Medical University
2018-2024
University of Southern California
2016-2022
Maine Farmland Trust
2021
J.P. Morgan
2021
Fujifilm (Japan)
2020
The University of Melbourne
2020
Herman Miller (United States)
2018
Jeonju University
2018
Korea University
2012
Stroke is the leading cause of adult disability worldwide, with up to two-thirds individuals experiencing long-term disabilities. Large-scale neuroimaging studies have shown promise in identifying robust biomarkers (e.g., measures brain structure) stroke recovery following rehabilitation. However, analyzing large rehabilitation-related datasets problematic due barriers accurate lesion segmentation. Manually-traced lesions are currently gold standard for segmentation on T1-weighted MRIs, but...
Background and Purpose- For stroke rehabilitation, task-specific training in animal models human rehabilitation trials is considered important to modulate neuroplasticity, promote motor learning, functional recovery. Little known about what constitutes an effective dosage of therapy. Methods- This a parallel group, 4 arms, single-blind, phase IIb, randomized controlled trial dosages arm therapy delivered outpatient setting chronically after stroke. Participants were into groups that varied...
Abstract We developed a computer vision-based three-dimension (3D) motion capture system employing two action cameras to examine fine hand motor skill by tracking an object manipulated hand. This study aimed the accuracy and feasibility of this approach for detecting changes in skill. conducted three distinct experiments assess system's feasibility. employed high-resolution, high-frame-rate cameras. evaluated our calculating 3D locations moving various directions. also examined identifying...
Lesion load of the corticospinal tract (CST-LL), a measure overlap between stroke lesion and CST, is one strongest predictors motor outcomes following stroke. CST-LL typically calculated by using probabilistic map CST originating from primary cortex (M1). However, higher order areas also have projections that contribute to control. In this retrospective study, we examined whether evaluating additional origins more strongly associated with post-stroke severity than M1 only. We found both...
In neurotypical individuals, arm choice in reaching movements depends on expected biomechanical effort, success, and a handedness bias. Following stroke, does change to account for the decreased motor performance, or it follow preinjury habitual preference pattern? Participants with mild-to-moderate chronic stroke who were right-handed before performed both spontaneous forced-choice blocks, under no-time, medium-time, fast-time constraint conditions designed modulate success. Mixed-effects...
Abstract Stroke is the leading cause of adult disability worldwide, with up to two-thirds individuals experiencing long-term disabilities. Large-scale neuroimaging studies have shown promise in identifying robust biomarkers (e.g., measures brain structure) stroke recovery following rehabilitation. However, analyzing large rehabilitation-related datasets problematic due barriers accurate lesion segmentation. Manually-traced lesions are currently gold standard for segmentation on T1-weighted...
The corticospinal tract (CST) is a crucial brain pathway for distal arm and hand motor control. We aimed to determine whether diffusion tensor imaging (DTI)-derived CST metric predicts upper extremity (UE) improvements in chronic stroke survivors.We analyzed clinical neuroimaging data from randomized controlled rehabilitation trial. Participants completed assessments at baseline 4 months later, postintervention. Using univariate linear regression analysis, we determined the relationship...
Up to two-thirds of stroke survivors experience persistent sensorimotor impairments. Recovery relies on the integrity spared brain areas compensate for damaged tissue. Deep grey matter structures play a critical role in control and regulation circuits. The goal this work is identify associations between volumes subcortical nuclei behaviour at different timepoints after stroke. We pooled high-resolution T1-weighted MRI scans behavioural data 828 individuals with unilateral from 28 cohorts...
Task conditions significantly impact human motor control. We investigated how task type, difficulty, and constraints influence the kinematics of goal-directed arm reaching. Non-disabled young adults performed two distinct reaching tasks: pointing picking up an object with chopsticks. These tasks were carried out under various conditions, including constrained unconstrained elbow extension different difficulties. collected kinematic data using a 3-D motion capture system analyzed effects on...
Motor performance and learning have distinct behavioral neural signatures can be uniquely modulated by various informational motivational factors. Contemporary frameworks describe four different motor mechanisms mapped onto specific regions which are key for skill acquisition: error-based (cerebellum), reinforcement (basal ganglia), cognitive strategies (prefrontal cortex), use-dependent (motor cortex). However, little is known about the circuits engaged during acquisition that specifically...
[Purpose] The aim of this study was to determine whether high frequency transcutaneous electrical nerve stimulation (HF-TENS) influences spasticity and motor function recovery after spinal cord injury (SCI). [Subjects] Thirty six male Sprague-Dawley rats (200-250 g) were received contusive SCI at T10 level. One week SCI, 20 with showed increased spasticity. Rats randomly assigned into two groups: the HF-TENS group (n=10) control (n=10). [Methods] (100 Hz, 200 μs) applied anterior tubercle...
The goal of the Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) Stroke Recovery working group is to understand brain and behavior relationships using well-powered meta- mega-analytic approaches. ENIGMA has data from over 1,800 stroke patients collected across 32 research sites 10 countries around world, comprising largest multi-site retrospective collaboration date. This paper outlines efforts taken by develop neuroinformatics protocols methods manage magnetic resonance...
Microstructural changes in the corpus callosum (CC) are associated with more severe motor impairment paretic hand, poor recovery, and general disability. The purpose of this study was to determine if CC microstructure predicts bimanual performance chronic stroke survivors.
ABSTRACT Background and Purpose Up to two-thirds of stroke survivors experience persistent sensorimotor impairments. Recovery relies on the integrity spared brain areas compensate for damaged tissue. Subcortical regions play critical roles in control regulation circuits. The goal this work is identify associations between volumes subcortical nuclei behavior at different timepoints after stroke. Methods We pooled high-resolution T1-weighted MRI scans behavioral data 828 individuals with...
Trunk compensation is the most common movement strategy to substitute for upper extremity (UE) motor deficits in chronic stroke survivors. There a lack of evidence examining how task conditions impact trunk and goal-directed arm reaching kinematics. This protocol aims investigate conditions, including difficulty complexity, on Two non-disabled young adults two survivors with mild UE impairment were recruited testing protocol. Each participant performed reaches four different (2 difficulties...
Abstract Background and Purpose For stroke rehabilitation, task-specific training in animal models human rehabilitation trials is considered important to trigger inherent neuroplasticity, promote motor learning, functional recovery. Little known, however, about what constitutes an effective dosage of therapy. Methods This a parallel group, four arm, single blind, phase I, randomized control trial dosages upper extremity therapy delivered outpatient setting during the chronic after stroke....
Abstract In non-disabled individuals, arm choice in pointing movements depends on expected biomechanical effort, success, and a handedness bias. Following stroke, is re-optimized to account for the decreased motor performance, or does it follow pre-injury habitual pattern? Because premorbidly right-handed individuals with left hemiparesis generally use their affected less than those right hemiparesis, we hypothesized that follows more pattern right-than left-hemiparetic individuals....
Trunk compensation is the most common movement strategy to substitute for upper extremity (UE) motor deficits in chronic stroke survivors. There a lack of evidence examining how task conditions impact trunk and goal-directed arm reaching kinematics. This protocol aims investigate conditions, including difficulty complexity, on Two non-disabled young adults two survivors with mild UE impairment were recruited testing protocol. Each participant performed reaches four different (2 difficulties...