Background Migraine and neck pain can be critical causes of disability. The contribution for the overall disability individuals with migraine remains unknown. Objective To contrast experienced by episodic chronic without as captured N eck D isability I ndex. Methods Disability due to was assessed using ndex in or seen at a university‐based headache center. Neck defined mild (score ranging from 5 14 points), moderate (15‐24 severe (25‐34 points) complete (35 points higher). compare...

Objectives This cross‐sectional study investigated potential differences in cervical musculature groups of migraine headaches vs. non‐headache controls. Differences muscle strength and antagonist coactivation during maximal isometric voluntary contraction (MIVC) were analyzed between individuals with subjects relationships force neck pain clinical aspects. Method A customized hand‐held dynamometer was used to assess flexion, extension, bilateral lateral flexion episodic ( n =31), chronic =...

To investigate the differences in pressure sensitivity cervical musculature including upper trapezius, sternocleidomastoid, suboccipital, levator scapulae, and anterior scalene muscles between women with migraine healthy controls.Cross-sectional study.Thirty 30 participated.Pressure pain thresholds (PPT) were bilaterally assessed over a blinded design. Mean values of both sides pooled for statistical analysis. Comparison groups was performed by unpaired Student t-test correlation headache...

To investigate the association between presence of self-reported neck pain in patients with migraine and clinical features, upper cervical mobility, muscle performance.A total 142 were recruited stratified by (n = 99) or absence 43). The examination included Migraine Disability Assessment, 12-item Allodynia Symptom Checklist, a flexion rotation test, Craniocervical Flexion Test.Migraine-related disability was reported more than 80% both groups (p 0.82). However, there greater prevalence...

Migraine patients have musculoskeletal disorders and pain in the cervical. And, despite pathophysiology demonstrating relationship between migraine cervical spine, effectiveness of craniocervical exercises these has not been verified. So, aimed this study was verify muscle-strengthening exercise (CMSE) reducing frequency intensity headache patients. METHODS: A two-armed, parallel-group randomized controlled trial with a 3-month follow-up performed. For eight weeks, volunteers intervention...

Objective To determine whether migraine interferes with health‐related quality of life ( HRQL ) and the degree disability caused by this condition in daily children both genders aged 6‐12 years. Background Migraine is a chronic disease recurrent symptoms that lead to reduction activity during crises intercritical periods, an impact on . Methods The sample consisted 50 without aura being treated at childhood headache outpatient clinic (study group) no history selected pediatric (control...

The role of musculoskeletal disorders the cervical spine in migraine is under debate.To investigate differences impairments neck including active global and upper mobility, presence symptomatic joints, cervicocephalic kinesthesia head/neck posture between women with episodic migraine, chronic controls.A cross-sectional study.Tertiary university-based hospital.Fifty-five 16 22 matched healthy women.Active range motion, mobility (i.e., flexion-rotation test), referred pain from (joint position...

ABSTRACT Objective To evaluate cutaneous allodynia among patients with chronic and episodic migraine in a tertiary headache clinic. Methods 80 subjects were assessed hospital. The 12-item Allodynia Symptom Checklist/Brazil questionnaire was applied to classify according the presence severity of allodynia. Results Cutaneous identified 81.3% group 92.5% (p = 0.03). No increased association could be attributed when adjusted by years disease (PR 1.12; 95%CI 0.99 1.27; p 0.06). groups also did...

The aim of this study was to assess kinesiophobia in patients with migraine and determine its association correlation cutaneous allodynia clinical manifestations migraine.A cross-sectional study.A headache clinic a university-based hospital.Eighty-nine diagnosed by neurologist specialized headache.Patients completed the Tampa Scale for Kinesiophobia (TSK) 12-item Allodynia Symptom Checklist (ASC-12) described frequency, duration, intensity attacks, as well number years migraine.The...

To assess the presence and handicap due to vestibular symptoms in three subgroups of patients with migraine controls.Women between 18-55 years old were diagnosed by headache specialists stratified as aura (n = 60), without chronic 60) controls 60). Information regarding demographics, collected this cross-sectional study. The self-perceived related was assessed through Dizziness Handicap Inventory questionnaire.A total 85% women had contrasted 70% group ( p < 0.05), 12% control reported...

This study examined the effect of GMP in two models depression mice. The immobility times forced swimming test (FST) and tail suspension (TST) were significantly reduced by (dose range: 5–50 mg/kg 5–100 mg/kg, i.p., respectively), without accompanying changes ambulation an open-field. I.c.v. injection (320-480 nmol/site) also FST affecting ambulation. mice treated with MK-801 (0.01 mg/kg) + (50 was not different from result obtained or alone, but (or MK-801) imipramine (15 treatment induced...

Migraine and temporomandibular disorders (TMDs) are reported to be associated. However, there no reports on the association among migraines, TMDs changes in body posture.To assess posture women suffering migraines with or without TMD compared a control group.Sixty-six mean age of 18 45 years participated this study. The groups were composed 22 volunteers migraine (MTMD), (MG) group (CG). Static was assessed by photogrammetry, 19 angles measured.Postural asymmetry observed face for 4 measured...

To investigate the relationship between presence of active trigger points (TrPs), craniocervical posture, and clinical features (frequency, intensity, duration) in patients with migraine.A cross-sectional study.Fifty migraine (90% women; age, 34.1 years) participated. Clinical data regarding were obtained. Trigger bilaterally explored following muscles: masseter, suboccipital, temporalis (anterior, medium, posterior fibers), sternocleidomastoid, upper trapezius, splenius capitis. Eight...

Since there was no Portuguese questionnaire to evaluate cutaneous allodynia, which has been pointed out as a risk factor of migraine, we aimed perform the cross-cultural adaptation 12 item Allodynia Symptom Checklist for Brazilian population and test its measurement properties. It consisted in six stages: translation, synthesis, back revision by specialist committee, pretest submission documents committee. In stage, applied 30 migraineurs both sexes, who had some difficulty understanding it....

Background Migraine, especially migraine with aura ( MA ), appears to be a risk factor for ischemic lesions in the posterior fossa. The clinical relevance of is uncertain. Accordingly, herein, we identified individuals , without MO and (controls) order investigate their balance mobility. Methods Participants were selected among patients seen an outpatient headache clinic. Controls had no history headache. Balance was assessed by measuring oscillation area using force plates mobility T imed U...

We compared the circulating levels of matrix metalloproteinase (MMP)-2, MMP-9, tissue inhibitors (TIMP)-1, TIMP-2, and MMP-9/TIMP-1 MMP-2/TIMP-2 ratios in migraine patients without aura (MWA) with (MA) those found healthy subjects (controls).We studied 80 (40 MWA 40 MA) women controls. Pro-MMP-2 were determined by zymography TIMP-1, TIMP-2 ELISA.While we similar levels, higher plasma pro-MMP-2 pro-MMP-2/TIMP-2 MA controls (P<0.05). Higher TIMP-1 lower MA, but not MWA, no significant...

Matrix metalloproteinases (MMP) are involved in the disruption of blood–brain barrier (BBB) during migraine attacks. In present study, we hypothesized that two functional polymorphisms (C− 1306T and C− 735T) MMP-2 gene haplotypes associated with modify tissue inhibitor MMP (TIMP)-2 levels migraine. Genotypes for were determined by real time-PCR using Taqman allele discrimination assays. Haplotypes inferred PHASE program. Plasma TIMP-2 concentrations measured gelatin zymography ELISA,...