A5067304508- Coronary Interventions and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Acute Myocardial Infarction Research
- Ophthalmology and Visual Impairment Studies
- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Retinal Imaging and Analysis
- Cardiac Imaging and Diagnostics
- Retinal and Optic Conditions
- Intraocular Surgery and Lenses
- Lipoproteins and Cardiovascular Health
- Cardiac Valve Diseases and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Retinopathy of Prematurity Studies
- Retinal and Macular Surgery
- Peripheral Artery Disease Management
- Venous Thromboembolism Diagnosis and Management
- Cardiac and Coronary Surgery Techniques
- Mechanical Circulatory Support Devices
- Atrial Fibrillation Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Acute Kidney Injury Research
- Acute Ischemic Stroke Management
Shanghai Eye Disease Prevention & Treatment Center
2016-2025
Shanghai First People's Hospital
2015-2025
Shanghai Jiao Tong University
2015-2025
Tongji University
2023-2024
General Hospital of Shenyang Military Region
2009-2024
Shanghai Clinical Research Center
2024
National Clinical Research
2021-2023
University of Lusaka
2021-2023
Center for Visual Communication (United States)
2023
Dalian University
2022
Purpose: We assessed changes in age-specific prevalence of refractive error at the time starting school, by comparing preschool and school age cohorts Shanghai, China. Methods: A cross-sectional study was done Jiading District, Shanghai during November December 2013. randomly selected 7 kindergartens primary schools, with probability proportionate to size. Chinese children (n = 8398) aged 3 10 years were enumerated, 8267 (98.4%) included. Children underwent distance visual acuity assessment...
China contributes to a significant proportion of the myopia in world. The study aims investigate utilization various correction methods and health service urban China, estimate cost treatment prevention. In addition, we aimed productivity loss due myopia.The was cross-sectional investigation carried out areas three provinces located east (Shanghai), middle (Anhui) west part (Yunnan) 2016. A total 23819 people aged between 5 50 years were included. Health analyzed from patients'...
Background Community-based telemedicine screening for diabetic retinopathy (DR) has been highly recommended worldwide. However, evidence from low- and middle-income countries (LMICs) on the choice between artificial intelligence (AI)–based manual grading–based is inadequate policy making. Objective The aim of this study was to test whether AI model more worthwhile than grading in community-based DR context labor costs urban China. Methods We conducted cost-effectiveness cost-utility analyses...
Abstract Importance Cohort studies could not only reveal associations between change of refractive components and onset/progression myopia, but also risk factors, which is important for understanding mechanism providing strategies. Background Prevalence myopia high in Shanghai, being reported to be 52.2% children aged 10 years old. Design study. Participants A total 1856 students from six randomly selected primary schools Baoshan District, Shanghai. Methods Children underwent comprehensive...
To report on: (a) overall myopia and high prevalence, (b) the impact of education on spherical equivalent refractive error in children across Shanghai.Cross-sectional study.Across all 17 districts Shanghai.910 245 aged 4-14 years from a school-based survey conducted between 2012 2013.Data with non-cycloplegic autorefraction, visual acuity assessment questionnaire were analysed (67%, n=6 06 476). Prevalence (≤-1.0 D) (≤-5.0 was determined. We used regression discontinuity design to determine...
Visual impairments and blindness are major public health concerns globally. Effective eye disease screening aided by artificial intelligence (AI) is a promising countermeasure, although it challenged practical constraints such as poor image quality in community screening. The recently developed ophthalmic foundation model RETFound has shown higher accuracy retinal recognition tasks. This study an RETFound-enhanced deep learning (DL) for multiple-eye using real-world images from screenings....
To explore macular perfusion changes in patients with rhegmatogenous retinal detachment (RRD) involved the macula following successful surgery and to evaluate correlation between blood flow density visual outcomes using optical coherence tomography angiography (OCTA). This retrospective study included 14 eyes (14 patients) macular-off RRD that underwent a standard three-port 23-gauge pars plana vitrectomy (PPV) intraocular gas tamponade combined phacoemulsification, aspiration, lens...
Dopamine and polyethyleneimine (PEI) copolymerized nanodots (PDA–PEI nanodots) with both fluorescence emission quenching features were synthesized by a simple one-step reaction at room temperature. By adjusting the dopamine PEI ratio as well chain length of PEI, properties PDA–PEI can be controlled well. Under optimal conditions, showed strong green an absolute quantum yield 1–2% efficiency more than 99% to several fluorophores wavelengths ranging from blue red light regions. The large...
The gut microbiota has emerged as an independent risk factor for diabetes and its complications. This research aimed to delve into the intricate relationship between microbiome diabetic retinopathy (DR) through a dual approach of cross-sectional prospective cohort studies. In our study investigation involving ninety-nine individuals with diabetes, distinct microbial signatures associated DR were identified. Specifically, profiling revealed decreased levels Butyricicoccus Ruminococcus torques...
The proprotein convertase subtilisin/kexin type 9 inhibitor alirocumab significantly reduces low-density lipoprotein cholesterol (LDL-C).This study (ODYSSEY EAST) assessed the efficacy and safety of vs ezetimibe in high cardiovascular risk patients from Asia.Patients (n = 615) China, India, Thailand with hypercholesterolemia at on maximally tolerated statin were randomized (2:1) to (75 mg every 2 weeks [Q2W]; dose increase 150 Q2W week 12 if 8 LDL-C was >1.81 mmol/L [>70 mg/dL]) or (10...
Abstract Purpose To document one‐year changes in refraction and refractive components preschool children. Methods Children, 3– 5 years old, the Jiading District, Shanghai, were followed for one year. At each visit, axial length (AL), under cycloplegia (1% cyclopentolate), spherical dioptres (DS), cylinder (DC), equivalent (SER) corneal curvature radius (CR) measured. Results The study included 458 right eyes of mean DS, DC SER 0.02 ± 0.35 D, −0.02 0.33 D 0.01 0.37 while AL, CR lens power...
Pixel pitch calibration is an essential step to make the fundus structures in image quantitatively measurable, which important for diagnosis and treatment of many diseases, e.g., diabetes, arteriosclerosis, hereditary optic atrophy, etc. The conventional approaches require specific parameters camera or several specially shot images chess board, but these are generally not accessible, results cannot be generalized other cameras. Based on automated ROI (region interest) disc detection,...
Abstract Background The association between remnant cholesterol (RC) and diabetic retinopathy (DR) in type 2 diabetes mellitus (T2DM) remains unclear. Morphological changes retinal vessels have been reported to predict vascular complications of diabetes, including DR. Methods This cross-sectional study included 6535 individuals with T2DM. RC value was calculated using the recognized formula. parameters were measured fundus photography. independent relationship DR analyzed binary logistic...
It is unclear how exposure to different types of screen content associated with early development among preschool children. This study aims precisely evaluate the time across and explore associations Ages Stages Questionnaire, Third Edition (ASQ-3) score 5 capacity domains in children aged 34.5-66 months. monitoring used intelligent technology collect data on 7-day spent viewing each type. The participants were 2 groups Shanghai kindergarten kids. collected between March 2023 July 2023....
In this paper, the calculation results and properties of determinants under hyperbolic complex numbers are studied. The number is a commutative ring consisting two real with zero divisors. This paper overcomes difficulty that contains divisors, calculates decomposition determinant by its property. investigates operation proves any can be decomposed into through factors. Based on decomposition, necessary sufficient conditions for invertibility further derived. addition, property product...
We obtained retinal nerve fiber layer (RNFL) thickness measurements in normal Chinese students aged 6 to 17 years, and investigated the relationship between RNFL sex, eye laterality, age, axial length, refractive error.A total of 4648 eyes 2324 normal, randomly-selected years was examined this study. The measured by optical coherence tomography. effects laterality (left or right), error, length on were assessed.The average age subjects 12.82 ± 3.11 years. global (±SD) 106.89 12.84 μm....
Purpose To explore the effectiveness of combining uncorrected visual acuity (UCVA) and noncycloplegic autorefraction (NCAR) for large-scale myopia screening in schoolchildren with a high prevalence myopia. Methods A total 1687 children aged between 6 12 years, from five primary schools Baoshan district Shanghai participated study. We measured UCVA before after cycloplegia by Topcon KR-8800. drew receiver operating characteristic curves to achieve best cutoff points their corresponding...
Nearly half of children suffering vision impairment reside in China with myopia accounting for the vast majority.To describe design and methodology Shanghai Child Adolescent Large-scale Eye Study (SCALE).The SCALE was a city wide, school-based, prospective survey.Children adolescents aged 4-14 years from kindergarten (middle senior), primary schools junior high all 17 districts counties Shanghai, were examined 2012-2013.Each enrolled child underwent assessment (distance visual acuity;...
Background/aims We aim to explore the effect of sympathetic nervous system (SNS) on choroid thickness (ChT) and axial length (AL). Methods Students grade 2 3 from a primary school were included followed for 1 year. Visual acuity, refraction, AL ChT measured. Morning urine samples collected determining SNS activity by analysing concentrations epinephrine, norepinephrine dopamine using liquid chromatography-tandem mass spectrometry. The most important factor (factor 1) was calculated analysis...
To examine the benefit of cataract surgery on visual acuity and vision related quality life in patients with stabilized vision-threatening diabetic retinopathy. A total 126 (153 eyes) who were diagnosed combined retinopathy underwent phacoemulsification. Measurements included best-corrected (BCVA), which was converted into a weighted logarithm minimum angle resolution (logMAR) (VRQoL) using Chinese-version low questionnaire (CLVQOL). Three months after phacoemulsification, statistically...
Background Coronary chronic total occlusion (CTO) remains one of the most challenging lesion subsets in interventional cardiology, even with development medical device and operator expertise. This study was conducted to examine relationship between characteristics procedural success incidence in-hospital major adverse cardiac events (MACE) after percutaneous coronary intervention (PCI) for CTO. Methods Clinical angiographic data 1263 patients CTO who underwent PCI June 1995 December 2005...