Reactive oxygen species have been implicated in the pathogenesis of contrast-induced nephropathy (CIN). We investigated relationship between CIN with paraoxonase 1 (PON-1) activity and oxidative stress markers (total antioxidant status [TAS], total oxidant [TOS], index [OSI]) patients anterior ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention; 289 consecutive STEMI were prospectively included. The divided into 2 groups: (n = 69) non-CIN...

The no-reflow phenomenon has a negative prognostic value in patients with acute ST-elevation myocardial infarction (STEMI). SYNTAX score (SS) quantifies the extent and complexity of angiographic disease predicts long-term mortality morbidity STEMI. We aimed to assess its possible relationships SS clinical characteristics STEMI treated primary percutaneous coronary intervention (PPCI).In this study, 880 PPCI were included prospectively (646 men 234 women, mean age 58.5±12.4 years). SS,...

It has been suggested that athero-thrombotic risk progressively increases as the glomerular filtration rate (GFR) declines. Mean platelet volume (MPV) is most commonly used measure of size, and higher MPV value independent factor for disease such myocardial infarction. We aimed to evaluate association between estimated GFR in patients with stable coronary artery showing normal mildly impaired renal function. A total 471 (288 males 183 females; mean age: 62.5 + 9.5 years) angiographically...

OBJECTIVE:Obstructive sleep apnea syndrome is associated with cardiovascular diseases and thromboembolic events.The mean platelet volume (MPV) a predictor of aim the present study to investigate association between MPV disease severity in patients obstructive syndrome.METHODS: We prospectively included 194 without (mean age 56.5 ± 12.5 years) who were undergoing tests.An overnight full laboratory polisomnography examination was conducted on each patient.The divided into 3 groups according...

We proposed a new technique for the treatment of coronary bifurcation lesions, called jailed semi-inflated balloon (JSBT).Currently, provisional approach is recommended to treat most lesions. However, it associated with risk side branch (SB) occlusion after main vessel (MV) stenting due plaque or carina shift into SB. The SB may cause peri-procedural myonecrosis hemodynamic compromise. Therefore, strategies are needed reduce during approach.Between September 2014 and April 2015, we selected...

Background. The high-sensitivity cardiac troponin T (hs-cTnT) assay provides important prognostic information on cardiovascular diseases. Although hs-cTnT is associated with left ventricle (LV) hypertrophy (LVH), it has not been investigated in different LV geometric patterns incorporating normal structure and concentric remodeling addition to LVH. Objectives. We aimed investigate the possible association between newly diagnosed hypertensive patients. Methods. studied 306 patients...

It has been demonstrated that the neutrophil/lymphocyte ratio (NLR) might be a useful marker to predict cardiovascular risk and events. We aimed investigate role of NLR ventricular remodeling (VR) in patients with anterior ST-elevation myocardial infarction (STEMI) who were treated primary percutaneous coronary intervention.We prospectively included 274 consecutive STEMI patients. Echocardiography was performed during admission at six months after infarction. VR defined as least 20% increase...

Vitamin D deficiency is an independent risk factor for cardiovascular mortality. The relationship between vitamin level and left ventricle (LV) myocardial performance index (MPI=Tei index), which incorporates both LV systolic function diastolic function, was not investigated in previous studies. We hypothesized that may be associated with geometry. aimed to investigate the association serum 25-hydroxyvitamin (25 [OH] D) levels MPI hypertrophy hypertensive patients newly diagnosed preserved...

Background: Compared to patients without a collateral supply, long-term cardiac mortality is reduced in with well-developed coronary circulation (CCC). Cardiovascular risk markers, such as N-terminal pro-brain natriuretic peptide (NT-proBNP), high-sensitive C-reactive protein (hs-CRP) and troponin T (hs-cTnT) are independent predictors for cardiovascular mortality. Objectives: The main goal of this study was examine the relationship between CCC markers. Methods: We prospectively enrolled 427...

In the pathogenesis of atherosclerosis, oxidative stress plays a major role in plaque instability, rupture, and erosion, which subsequently leads to thrombus formation causes total infarct-related artery (IRA) occlusion. We investigated relationship between spontaneous reperfusion (SR) IRA patients with anterior ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention. A 341 consecutive STEMI were prospectively included present study. Patients...

Vitamin D may modulate vascular inflammation, smooth muscle cell proliferation, the renin-angiotensin system, and cardiomyocyte myocardial fibrosis, proliferation. These mechanisms play a role on arterial stiffness left ventricle hypertrophy (LVH) in hypertensive patients. We aimed to evaluate association between serum vitamin with LVH patients hypertension.We studied 133 newly diagnosed hypertension [mean (SD) age, 62.9 (10.6) years]. Pulse wave velocity (PWV), which reflects stiffness, was...

Background. Gamma glutamyl transferase (GGT) is involved in the pathophysiologic process of coronary atherosclerosis. GGT activity plays a role catabolism glutathione which known as one major antioxidants. However, there lack research on direct examination relevance between serum with systemic oxidative stress. Objectives. We aimed to investigate relationship stress markers and extent complexity artery disease (CAD) assessed SYNTAX score stable CAD. Methods. Measurements were obtained from...

Obstructive sleep apnea (OSA) is an independent risk factor for cardiovascular morbidity and death. Little information available regarding the relationship between severity of OSA myocardial performance in patients who have normal ejection fractions. We prospectively investigated this relationship, using tissue-Doppler index (TD-MPI). conducted overnight, full-laboratory polysomnographic examinations 116 patients, calculated left right ventricular TD-MPIs. Patients were classified into 3...

We investigated the association between serum bilirubin level and thoracic aortic intima-media thickness (IMT). The study population consisted of 417 patients without coronary artery disease, who underwent transesophageal echocardiography examination for various indications. highest IMT values were observed in bilirubinlow group compared with bilirubinhigh (P < .001). Serum was associated high-density lipoprotein cholesterol (r = .162, P .001), high-sensitivity C-reactive protein (hsCRP; r...

Background There are limited number of studies about relationship between serum vitamin D level and presence severity coronary artery disease (CAD). We assessed the extent complexity CAD by SYNTAX score 25‐hydroxyvitamin in patients with stable CAD. Methods In study, 209 consecutive (age: 63.1 ± 10.0 years) 102 healthy control subjects (age 61.3 13.7 were included. Serum was measured using a direct competitive chemiluminescent immunoassay other biochemical markers all subjects. All underwent...

Existing evidence suggests that impaired vitamin D metabolism contribute to the development of atherosclerosis. Aortic intima-media thickness (IMT) is an earlier marker than carotid IMT preclinical However, there a lack researches on direct investigation relevance between serum 25-hydroxyvitamin (25(OH)D) and thoracic aortic IMT. In this study, we aimed assess relationship 25(OH)D.We studied 117 patients (mean age: 45.5 ± 8.4 years) who underwent transesophageal echocardiography (TEE) for...

Epicardial adipose tissue is related to coronary atherosclerosis, left ventricle hypertrophy, myocardial dysfunction, cardiomyopathy, and inflammation, which produces a variety of cytokines that influence key pathogenic mechanisms atherogenesis. The main goal this study examine the relationship between epicardial fat thickness (EFT) cardiovascular risk markers as well complexity artery disease (CAD) in patients with stable CAD.We prospectively included 439 CAD undergoing angiography present...

Background Left ventricular (LV) remodeling is an important pathophysiological event that develops following acute myocardial infarction and causes LV systolic dysfunction. Mechanisms such as apoptosis, necrosis, oxidative stress play role in remodeling. Objectives This study aimed to determine the relationship between development of apoptosis marker M30 patients with anterior ST-segment elevation (STEMI) who were treated primary percutaneous coronary intervention (PCI). Materials methods...