A5080657992- Pharmacological Effects of Natural Compounds
- Traditional Chinese Medicine Analysis
- Natural product bioactivities and synthesis
- Signaling Pathways in Disease
- Cardiac Fibrosis and Remodeling
- Plant-based Medicinal Research
- Viral Infections and Immunology Research
Yunnan University
2025
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
2022-2024
Xuefu Zhuyu Capsule (XFZYC) plays a pivotal role in treating coronary heart disease (CHD) because of its potent clinical effects and fewer side effects. However, the possible pharmacological effect on CHD is limited. Thus, this research systematically analyzes XFZYC through network pharmacology technology. We identified 139 active compounds 127 overlapped target genes 11 herbs by using pharmacology, these regulated major signaling pathways related to CHD. The analysis protein-protein...
Objective. This study is aimed at exploring the molecular mechanism of Shufeiya recipe in treatment pulmonary hypertension (PH) using network pharmacology and docking analysis. Methods. Active components their target proteins were screened TCMSP database. PH-related core GeneCards, STRING database, Cytoscape-v3.8.2. Common obtained by intersection these active pH-related proteins. Rx64 4.0.2 software was used to perform GO functional enrichment analysis KEGG pathway on common obtain...
Abstract Background Optimized New Shengmai Powder (ONSMP) is a traditional Chinese medicine formula with significant anti-heart failure and myocardial fibrosis effects, but the specific molecular biological mechanisms are not fully understood. Methods In this study, we first used network pharmacology to analyze ONSMP's active ingredients, core signaling pathways, targets. Second, calculate affinity binding modes of ONSMP components targets using docking. Finally, heart rat model was...