Pablo Billeke

ORCID: 0000-0003-4261-0678
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About
Contact & Profiles
Research Areas
  • Neural and Behavioral Psychology Studies
  • Functional Brain Connectivity Studies
  • Neural dynamics and brain function
  • Autism Spectrum Disorder Research
  • Memory and Neural Mechanisms
  • EEG and Brain-Computer Interfaces
  • Multiple Sclerosis Research Studies
  • Neuroendocrine regulation and behavior
  • Psychology of Moral and Emotional Judgment
  • Action Observation and Synchronization
  • Olfactory and Sensory Function Studies
  • Neuroscience and Neuropharmacology Research
  • Neuroscience and Music Perception
  • Mental Health Research Topics
  • Attention Deficit Hyperactivity Disorder
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Surgical Simulation and Training
  • Psychosomatic Disorders and Their Treatments
  • Experimental Behavioral Economics Studies
  • Neuroscience and Neural Engineering
  • Heart Rate Variability and Autonomic Control
  • Face Recognition and Perception
  • RNA regulation and disease
  • Child and Adolescent Psychosocial and Emotional Development
  • Music Therapy and Health

Universidad del Desarrollo
2016-2025

Universidad del Desarrollo del Estado de Puebla
2019-2024

Valparaiso University
2024

Clínica Las Condes
2024

Gobierno de Chile
2024

Pontificia Universidad Católica de Chile
2012-2015

Instituto de Neurociencia Biomédica
2015

Recursive social decision-making requires the use of flexible, context-sensitive long-term strategies for negotiation. To succeed in bargaining, participants' own perspectives must be dynamically integrated with those interactors to maximize self-benefits and adapt other's preferences, respectively. This is a prerequisite develop successful self-other integration strategy. While such form strategic interaction critical decision-making, little known about its neurocognitive correlates. bridge...

10.1093/brain/aww231 article EN Brain 2016-09-27

Social cognition consists of several skills which allow us to interact with other humans. These include social stimuli processing, drawing inferences about others' mental states, and engaging in interactions. In recent years, there has been growing evidence cognitive impairments patients schizophrenia. Apparently, these are separable from general neurocognitive impairments, such as attention, memory executive functioning. Moreover, seems be a main determinant functional outcome could used...

10.3389/fpsyt.2013.00004 article EN cc-by Frontiers in Psychiatry 2013-01-01

Abstract Whether maximizing rewards and minimizing punishments rely on distinct brain systems remains debated, given inconsistent results coming from human neuroimaging animal electrophysiology studies. Bridging the gap across techniques, we recorded intracerebral activity twenty participants while they performed an instrumental learning task. We found that both reward punishment prediction errors (PE), estimated computational modeling of choice behavior, correlate positively with broadband...

10.1038/s41467-021-23704-w article EN cc-by Nature Communications 2021-06-07

Humans often face the challenge of making decisions between ambiguous options. The level ambiguity in decision-making has been linked to activity parietal cortex, but its exact computational role remains elusive. To test hypothesis that cortex plays a causal computing probabilities, we conducted consecutive fMRI and TMS-EEG studies. We found participants assigned unknown probabilities objective elevating uncertainty their decisions. Parietal correlated with degree process underestimates...

10.1371/journal.pbio.3002452 article EN cc-by PLoS Biology 2024-01-10

Patients recovering from COVID-19 commonly exhibit cognitive and brain alterations, yet the specific neuropathological mechanisms risk factors underlying these alterations remain elusive. Given significant global incidence of COVID-19, identifying that can distinguish individuals at developing is crucial for prioritizing follow-up care. Here, we report findings a sample patients consisting 73 adults with mild to moderate SARS-CoV-2 infection without signs respiratory failure 27 infections...

10.1038/s41598-024-69772-y article EN cc-by-nc-nd Scientific Reports 2024-08-17

In social interactions, the perception of how risky our decisions are depends on we anticipate other people's behaviors. We used electroencephalography to study neurobiology risk, in subjects playing role proposers an iterated ultimatum game pairs. Based statistical modeling, previous behaviors both players separate high-risk [HR] offers from low-risk [LR] offers. The HR present higher rejection probability and entropy (variability possible outcome) than LR Rejections elicited a stronger...

10.1093/cercor/bhs269 article EN Cerebral Cortex 2012-08-31

Abstract A dysfunction in the excitatory–inhibitory (E/I) coordination neuronal assembly has been proposed as a possible neurobiological mechanism of Autistic Spectrum Disorder (ASD). However, potential impact this cognitive performance is not fully explored. Since main consequence E/I an impairment oscillatory activity and its underlying computations, we assessed electroencephalographic ASD typically developing (TD) subjects during working-memory task. We found that committed more errors...

10.1038/s41598-017-14744-8 article EN cc-by Scientific Reports 2017-10-24

During social bargain, one has to both figure out the others’ intentions and behave strategically in such a way that behaviors will be consistent with one’s expectations. To understand neurobiological mechanisms underlying these behaviors, we used electroencephalography while subjects played as proposers repeated ultimatum game. We found adapted their offers obtain more acceptances last round this adaptation correlated negatively prefrontal theta oscillations. People higher activity related...

10.1093/scan/nsu012 article EN Social Cognitive and Affective Neuroscience 2014-02-03

Abstract Attentional mechanisms have been studied mostly in specific sensory domains, such as auditory, visuospatial, or tactile modalities. In contrast, attention to internal interoceptive visceral targets has only recently begun be studied, despite its potential importance emotion, empathy, and self‐awareness. Here, we the effects of shifting heart using a cue‐target detection paradigm during continuous EEG recordings. Subjects were instructed count either series visual stimuli (visual...

10.1111/psyp.12894 article EN Psychophysiology 2017-05-31

Adaptive behavior requires the comparison of outcome predictions with actual outcomes (e.g., performance feedback). This process monitoring is computed by a distributed brain network comprising medial prefrontal cortex (mPFC) and anterior insular (AIC). Despite being consistently co-activated during different tasks, precise neuronal computations each region their interactions remain elusive. In order to assess neural mechanism which AIC processes feedback, we recorded electrophysiological...

10.1093/cercor/bhaa017 article EN Cerebral Cortex 2020-01-19

Abstract Social cognition refers to the brain mechanisms by which we process social information about other humans and ourselves. Alterations in interpersonal functioning are common major depressive disorder, though only poorly addressed current pharmacotherapies. Further standardized tests, such as depression ratings or neuropsychologic used routine practice provide very little on skills, schemas, attributions, stereotypes judgments related interactions. In this article, review recent...

10.2478/s13380-013-0147-9 article EN cc-by-nc-nd Translational Neuroscience 2013-12-01

Intra-individual variability of Response Times (RTisv) is considered as potential endophenotype for Attentional Deficit/Hyperactivity Disorder (ADHD). Traditional methods estimating RTisv lose information regarding (RTs) distribution along the task, with eventual effects on statistical power. Ex-Gaussian analysis captures dynamic nature RTisv, normal and exponential components RT distribution, specific phenomenological correlates. Here, we applied ex-Gaussian to explore whether...

10.3389/fpsyt.2014.00197 article EN cc-by Frontiers in Psychiatry 2015-01-12

Abstract Working Memory (WM) impairment is the most common cognitive deficit of patients with Multiple Sclerosis (MS). However, evidence its neurobiological mechanisms scarce. Here we recorded electroencephalographic activity twenty relapsing-remitting MS and minimal deficit, 20 healthy control (HC) subjects while they solved a WM task. In spite similar performance, HC group demonstrated both correlation between temporoparietal theta memory load, medial frontal successful performances. did...

10.1038/s41598-020-66279-0 article EN cc-by Scientific Reports 2020-06-09

Abstract Background The ageing population has increased the prevalence of disabling and high-cost diseases, such as dementia mild cognitive impairment (MCI). latter can be considered a prodromal phase some dementias critical stage for interventions to postpone functionality. Working memory (WM) is pivotal function, representing fundamental element executive functions. This project proposes an intervention protocol enhance WM in these users, combining training with transcranial electrical...

10.1186/s13063-024-07972-7 article EN cc-by Trials 2024-02-23

The capacity to inhibit prepotent and automatic responses is crucial for proper cognitive social development, inhibitory impairments have been considered be key some neuropsychiatric conditions. One of the most used paradigms analyze processes Go-Nogo task (GNG). This has widely in psychophysical EEG studies, more recently using fMRI. However, a technical limitation that time resolution fMRI poorer than technique. In order compensate these temporal constraints, it become common practice...

10.1371/journal.pone.0087232 article EN cc-by PLoS ONE 2014-01-29

Introduction Decision-making is a process that can be strongly affected by social factors. Evidence has shown how people deviate from traditional rational-choice predictions under different levels of interactions. The emergence prosocial decision-making, defined as any action addressed to benefit another individual even at the expense personal benefits, been reported an example such influence. Furthermore, brain evidence involvement structures prefrontal cortex, anterior insula, and...

10.3389/fpsyt.2023.1160209 article EN cc-by Frontiers in Psychiatry 2023-07-13

During childhood, schools are a crucial environment for social interactions, making them ideal forevaluating the inclusion of children with special educational needs (SEN). Children AutismSpectrum Disorder (ASD) often face challenges in peer relationships, yet how this condition impactsspecific dynamics and school coexistence is not well understood. To address issue, weexamined relationships within elementary schools. We hypothesized that,compared to their peers without ASD, ASD: (i) occupy...

10.31234/osf.io/qpg4k preprint EN 2025-01-14

Multiple sclerosis (MS) is a prevalent neurological disorder marked by inflammation and demyelination, with fatigue being one of the most reported debilitating symptoms. While occurs across various conditions even in healthy individuals, specific mechanisms contributing to each context remain unclear. In this study, we conducted cross-sectional analysis involving 32 people relapsing MS (PwRMS) 29 controls who fatigue. Participants underwent MRI scans, including T1-weighted diffusion-weighted...

10.1038/s41598-025-01465-6 article EN cc-by-nc-nd Scientific Reports 2025-05-12
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