The association between subclinical hypothyroidism and cardiovascular disease the beneficial effect of levothyroxine replacement in are still under debate. present study was designed to determine whether is associated with an increase intima-media thickness common carotid artery (C-IMT) thyroid hormone can reverse this change C-IMT. Patients newly-diagnosed (n=36) overt (n=40) healthy euthyroid individuals (n=32) participated study. All patients were examined for clinical characteristics,...

The objectives of this study were to identify the clinical features and chest computed tomography (CT) findings coronavirus disease 2019 (COVID-19) patients compare characteristics diagnosed in Wuhan other areas China by integrating reported previous studies.We conducted a proportion meta-analysis integrate results studies identified online databases, subsequently compared overlapping 95% confidence intervals (CIs) between locations diagnosis. heterogeneity included was also...

The incidence of clinically undiagnosed obstructive sleep apnea (OSA) is high among the general population because limited access to polysomnography. Computed tomography (CT) craniofacial regions obtained for other purposes can be beneficial in predicting OSA and its severity.

Background and Objectives: Inconsistencies in nasal nitric oxide (nNO) values, due to anatomical variations comorbidities, challenge the accurate assessment of upper airway inflammation severity. We hypothesized that changes nNO levels following treatment for chronic rhinitis would be consistent provide relative value. This study aimed evaluate correlation between symptomatic improvements rhinitis.Methods: prospective observational included 46 participants diagnosed with December 2021...

The prevalence of type 2 diabetes in young adults and adolescents has increased the last decade according to increasing obese population. aim this study was examine clinical characteristics patients diagnosed with mellitus before age 40 years as compared at older ages.This a cross-sectional, retrospective using data from 350 diabetic who were an outpatient setting between January 2005 December 2007. Patients criteria set forth by American Diabetes Association. We examined laboratory through...

Although there have been many therapeutic options for allergic disease, the true allergen desensitization remains a challenging goal. The classic immunotherapy has limited efficacy, is inconvenient, and risk of anaphylaxis. Recent reports revealed that immunostimulatory DNA sequences (ISS-oligdeoxynucleotide [ODN], CpG motif) act as strong Th1 response-inducing adjuvants DNA-based vaccination might be an effective option. In this study, we investigate whether ISS-ODN/Dermatophagoides farinae...

Objectives Postulated etiologies for idiopathic sudden sensorineural hearing loss (SSNHL) include viral cochleitis, microvascular events. If SSNHL is caused by vascular compromise of common cochlear artery that supplies cochlea and posterior semicircular canal (PC), PC also can be damaged with cochlea. We aim to evaluate the prognostic value function in relation recovery SSNHL. Methods Seventy-six patients who were diagnosed treated underwent video head impulse test (vHIT) follow-ups more...

Glucocorticoids are considered the first-line therapy for sudden sensorineural hearing loss. But there is currently no consensus on administering them as a single dose versus multiple divided daily doses.We aim to evaluate treatment outcome of loss between single-dose and doses steroid treatment.A total 94 patients who were diagnosed treated followed up more than three months reviewed retrospectively. Patients into divided-dose groups, based their medication regimens. Hearing thresholds...

The olfactory epithelium is the main end organ for sense of smell in humans and vertebrates. Specially differenciated neuronal cells called receptor neurons (ORNs) play a key role by expressing receptors (ORs) on their apical surface membrane. ORs are G-protein coupled that transmit signals from odorants to ORNs molecular cascades using cyclic adenosine monophosphate, calcium ions other molecules, which result depolarization ORN. Unlike mammalian animals, only about 30% OR genes human genome...

Objectives. Human amniotic membrane extract (AME) is known to contain numerous bioactive factors and anti-inflammatory substances. However, the effects of AME on middle ear (ME) mucosa are unclear. This study assessed growth ME in response bacterially-induced otitis media (OM).Methods. OM was induced by inoculating nontypeable <i>Haemophilus influenzae</i> (NTHi) into cavity rats. mucosal explants were cultured concentrations 0, 5, 10, or 50 μg/mL. The area explant outgrowth...

Background/Aim: This study aimed to investigate changes in the tracheal mucosa after thyroidectomy, that can be a cause of post-thyroidectomy discomfort. Materials and Methods: Forty rats were divided into normal controls 3 surgical groups: (i) thyroid isthmectomy with cauterization, (ii) by cold instrument without hemostasis, (iii) sham (exposure trachea gland thyroidectomy dissection through pretracheal fascia). Animals euthanized at 1 4 weeks. Mucosal edema glandular hyperplasia measured....

본 연구에서는 열가소성 복합재료인 유리섬유/폴리프로필렌 복합재료를 이용한 복합재료 고정판의 적절한 성형조건을 찾기 위해 다양한 성형조건으로 제작된 시편의 인장실험과 굽힘실험을 수행하여 성형조건에 따른 기계적 거동을 비교하였다. 실험 결과 성형온도와 압력이 각각 <TEX>$230^{\circ}C$</TEX>, 3MPa일 때 가장 우수한 특성을 가짐을 확인하였다. 성형실험을 통해 결정된 성형방법으로는 스크류 구멍을 한번에 성형하는 정형성형방법과 후가공하는 방법을 사용하였으며, 성형실험과 굽힘실험 후가공 하는 경우 굽힘특성을 가지는 것을 논문에서는 성형을 복합재료의 기초 성형정보와 그에 고정판 성형에 대한 연구를 수행하였으며, 이 결과는 해당재료를 구조물 중요한 정보를 제공할 것으로 기대된다. In this paper, tensile and bending tests of glass/polypropylene composite (Twintex) specimens fabricated...

Transient receptor potential (TRP) protein is a superfamily of cation channels which have 6 trans-membrane domains and mainly pass calcium ion through themselves. There are seven types subfamilies in the TRP superfamily. can be activated by various kinds stimuli. Some polymodal receptors because two or more stimuli activate same type channels. proteins play roles living organism as for sensing outside inside local itself, signal conductors, trans-ducers. Especially, key thermosensation,...

혈관내 유두양 혈관내피세포 증식증(intravascular papillary endothelial hyperplasia, IPEH)은 혈관내피세포의 과도한 유 두양 증식을 특징으로 하는 혈관성 병변으로, Masson이 1923년 처음으로 보고할 당시 양성 종양으로 간주되어 Masson’s tumor 혹은 hemangioma 등으로도 불렸으나, 이후 여러 보 고들을 통해 종양이라기보다는 혈관 내에 발생하는 반 응성 병변으로 생각되고 있다. 혈관내피세 포 증식증은 신체 어느 부위에서나 발생할 수 있으나 매우 드 문 빈도를 보이며, 비과 영역에서 국내에 보고된 증례는 하비갑 개에 발생한 경우와 비강 측벽에 경우의 두 예에 불과 하다. 저자들은 비출혈로 내원한 환자에서 상악동에 증식증의 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. 증 례