Patrick Yousif

ORCID: 0000-0003-4277-6512
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About
Contact & Profiles
Research Areas
  • Systemic Lupus Erythematosus Research
  • Osteoarthritis Treatment and Mechanisms
  • Inflammatory Biomarkers in Disease Prognosis
  • Psoriasis: Treatment and Pathogenesis
  • Pregnancy and Medication Impact
  • Autoimmune and Inflammatory Disorders Research
  • MicroRNA in disease regulation
  • COVID-19 and healthcare impacts
  • Cardiac tumors and thrombi
  • Infective Endocarditis Diagnosis and Management
  • Eosinophilic Esophagitis
  • Peripheral Neuropathies and Disorders
  • Inflammasome and immune disorders
  • Pericarditis and Cardiac Tamponade
  • Reproductive System and Pregnancy
  • Kawasaki Disease and Coronary Complications
  • Cancer-related molecular mechanisms research
  • Parkinson's Disease and Spinal Disorders
  • Extracellular vesicles in disease
  • Lymphoma Diagnosis and Treatment
  • Viral-associated cancers and disorders
  • Hematological disorders and diagnostics
  • Pneumothorax, Barotrauma, Emphysema
  • Radiomics and Machine Learning in Medical Imaging
  • Spondyloarthritis Studies and Treatments

Henry Ford Health System
2024

Michigan United
2024

Case Western Reserve University
2022-2023

University Hospitals of Cleveland
2022-2023

University School
2022-2023

Wayne State University
2019-2020

Detroit Medical Center
2019-2020

Sinai Grace Hospital
2020

Objective Morbidity and mortality in rheumatoid arthritis (RA) is partly mitigated by maintaining immune hematologic homeostasis. Identification of those at risk challenging. Red cell distribution width (RDW) absolute lymphocyte count (ALC) associate with cardiovascular disease (CVD) the general population, activity RA. How these variables relate to inflammation RA was investigated. Methods In a retrospective single Veterans Affairs (VA) Rheumatology Clinic cohort 327 patients treated...

10.3899/jrheum.211411 article EN The Journal of Rheumatology 2022-11-01

BACKGROUND:Systemic lupus erythematosus (SLE) is a common autoimmune disorder in women of childbearing age. It can present during pregnancy and may lead to poor maternal fetal outcomes with higher risk preterm birth pre-eclampsia. Women are at flares pregnancy, especially if undiagnosed or disease poorly controlled. Cardiac tamponade rare complication SLE be fatal. CASE REPORT:A 21-year-old primigravida African-American female history asthma presented progressive pleuritic left shoulder...

10.12659/ajcr.936273 article EN American Journal of Case Reports 2022-05-26

BACKGROUND:Primary mediastinal diffuse large B cell lymphoma (DLBCL) presenting as a intracardiac tumor is extremely rare and has not been significantly reported in the literature. Cardiac consists of 2 subtypes: DLBCL invading heart primary cardiac lymphoma. Both subtypes have poor prognosis are treated similarly. Mediastinal life-threatening condition that, if diagnosed early, better survival rate. This case right atrium mass, causing partial obstruction tricuspid valve without hemodynamic...

10.12659/ajcr.917159 article EN American Journal of Case Reports 2019-12-06

Abstract Background Osteoarthritis (OA) and rheumatoid arthritis (RA) are prevalent forms of arthritis. Early detection OA RA is challenging with existing methods, which can delay effective management. MicroRNAs small molecules that have emerged as promising disease biomarkers the potential to improve early differentiation subtypes. In this study we aimed identify distinct circulating microRNAs in plasma from individuals RA, using an unbiased microRNA-sequencing approach. Methods Plasma...

10.1101/2024.12.10.24318813 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2024-12-11

[b]BACKGROUND[/b] Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by autoantibody production leading to inflammation in multiple organs; it commonly affects young women their child-bearing years. Clinical manifestations are diverse and range from mild arthritis diffuse alveolar hemorrhage (DAH). DAH a rare devastating complication of SLE that carries mortality rate up 50%, despite aggressive therapy. [b]CASE REPORT[/b] A 21-year-old primigravida at 16 weeks...

10.12659/ajcr.921299 article EN American Journal of Case Reports 2020-02-29

BACKGROUND:Sarcoidosis is a systemic inflammatory disorder characterized by classic pathologic feature of non-caseating granulomas involving any organ system. Hemophagocytic lymphohistiocytosis (HLH) catastrophic cytokine surge dysregulation the macrophage response, which can be rapidly fatal. Recognition HLH has been increasing over past decade. present with features sepsis that make diagnosis challenging and requires high clinical suspicion. CASE REPORT:We report case 48-year-old African...

10.12659/ajcr.921306 article EN American Journal of Case Reports 2020-04-21
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