About
Contact & Profiles
A5084567783
Research Areas
- Pancreatic function and diabetes
- Diabetes and associated disorders
- Diet, Metabolism, and Disease
- Pancreatitis Pathology and Treatment
- Endoplasmic Reticulum Stress and Disease
Universidade de São Paulo
2021-2024
In type 1 diabetes (T1D) development, proinflammatory cytokines (PIC) released by immune cells lead to increased reactive oxygen species (ROS) production in β-cells. Nonetheless, the temporality of events triggered and role different ROS sources remain unclear. Isolated islets from C57BL/6J wild-type (WT), NOX1 KO NOX2 mice were exposed a PIC combination. We show that increase O2•− after 2 h WT but not islets. Using transgenic constitutively expressing genetically encoded compartment...
10.3390/antiox10081305
article
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Antioxidants
2021-08-18
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