A5068164550- Probiotics and Fermented Foods
- Gut microbiota and health
- Hepatitis C virus research
- Cancer Research and Treatments
- Hepatitis B Virus Studies
- Viral gastroenteritis research and epidemiology
- Immune Response and Inflammation
- Animal Diversity and Health Studies
- Polysaccharides and Plant Cell Walls
- Cancer, Hypoxia, and Metabolism
- Liver Disease Diagnosis and Treatment
- Protein Hydrolysis and Bioactive Peptides
- Pancreatic and Hepatic Oncology Research
- Seaweed-derived Bioactive Compounds
- Drug Solubulity and Delivery Systems
- Malaria Research and Control
- Nanoparticle-Based Drug Delivery
- Biological Activity of Diterpenoids and Biflavonoids
- Cancer Treatment and Pharmacology
- Microbial Metabolites in Food Biotechnology
- Diabetes and associated disorders
- Pneumonia and Respiratory Infections
- Cancer, Stress, Anesthesia, and Immune Response
- Cancer Mechanisms and Therapy
- Dengue and Mosquito Control Research
Agricultural Genetic Engineering Research Institute
2017-2024
King Abdulaziz University
2013-2021
Vacsera (Egypt)
2018
Probiotics are commensals with special characteristics that essential for the development of immune system, and may protect mucosal surfaces against pathogens. In this study, a total 40 lactic acid bacteria (LAB) were isolated from different raw fermented camel's milk samples collected Saudi Arabia (Makkah area) Egypt (Fayoum), tested probiotic properties. Among them, Pro 4 7 isolates exhibited excellent potential including bile salt (0.2-0.6%), phenol tolerance (0.2-0.4%) (0.0-10%)....
Little is known about the prevalence of HBV genotypes/sub-genotypes in Jeddah province, although hepatitis B virus (HBV) was identified as most predominant type Saudi Arabia. To characterize genotypes/sub-genotypes, serum samples from 15 patients with chronic were collected and subjected to HBsAg gene amplification sequence analysis. Phylogenetic analysis sequences revealed that 11 (48%) isolates belonged HBV/D while 4 (18%) associated HBV/C. Notably, a sub-genotype phylogenetic tree eight...
Numerous dietary products are supplemented with probiotics that may be beneficial for human health. Recently, bifidobacteria have received increasing attention as a genus of probiotic bacteria high efficiency and few side effects. To examine potential effects different concentrations on the mucosal immune response, we fed mice (a) 108 colony-forming units (CFU) (group 108B), (b) 1012 CFU 1012B) over 42 days assessed gene expression in intestinal mucosa marker serum samples; ten untreated...
Chronic hepatitis C virus (HCV) infection and its progression are major health problems that many countries including Saudi Arabia facing. Determination of HCV genotypes subgenotypes is critical for epidemiological clinical analysis aids in the determination ideal treatment strategy needs to be followed expected therapy response. Although has been identified as second most predominant type Arabia, little known about molecular epidemiology genetic variability circulating Jeddah province...
The objective was to explore the therapeutic potential of carrageenan and soy protein in treating colorectal cancer (CRC) by selectively targeting cells modulating chemokine receptor CXCR-4.The CXCR-4 plays a crucial role colon promoting tumor cell proliferation, metastasis, angiogenesis.Therefore, expression could be promising approach for treatment.We conducted experiments using two groups HCT-116 cells.The CS-HCT group treated with combination protein, while untreated Group UHCT served as...
5-Fluorouracil (5-FU) is the most common anticancer therapeutic, even though its response rate as a single agent usually less than 20%. Lactobacillus rhamnosus bacteria reduce severity of gastrointestinal tract infections, with additional functions in cancer prevention. This study investigated histological and immunological changes associated combination treatment L. 5-FU mice colon cancer.Five groups male were classified follows; Group A: Mice injected azoxymethane (AOM) to induce cancer,...
Probiotics have attracted considerable attention because of their ability to ameliorate disease and prevent cancer. In this study, we examined the immunomodulatory effects a Streptococcus thermophilus probiotic on intestinal mucosa azoxymethane-induced colon Sixty female mice were divided into four groups (n = 15 each). One group untreated was used as control (C group). Another mouse injected with azoxymethane once weekly for 8 weeks induce cancer (CC Finally, two continuously treated twice...
Since the discovery of Agarwood (Incense tree), many studies reported its characteristic effects and variable benefits, as either to produce Arabian Incense or a traditional medicine against diseases. Laboratory experiments were carried out on effect different concentrations smoke inhalation lung weight tissue in female mice. This researchderives importance from fact that is heavily used Saudi Arabia absence thorough health. Eighty animals areusedin this study, aredivided into four groups,...
A B S T R C Hepatitis virus (HBV) infection remains to be a worldwide health problem.In Saudi Arabia, HBV is the most predominant type of hepatitis followed by and while little known about molecular epidemiology prevalence genotype/subgenotype particularly in Jeddah.Serum samples were collected from chronic patients subjected HBsAg gene amplification.Sequencing phylogenetic analysis entire sequences revealed that 11 isolates belonged HBV/D 4 associated with HBV/C.Interestingly, subgenotypes...
Background and Objective: Dengue is the most important arthropod-borne viral disease which caused by four-dengue virus serotypes (1-4) its incidence has grown dramatically around world in recent decades.This study was conducted to determine molecular characterization of dengue genotypes spreading Jeddah province.Methodology: To distinguish genotypes, serum samples from 13 infected patients were subjected envelop non-structural 1 (E/NS1) gene amplification sequence analysis at nucleotide...
Meningitis is an inflammation of the meninges, which are three membranes that cover brain and spinal cord; occurs when fluid surrounding meninges becomes infected.Meningitis a life-threatening disease, particularly in older people immunocompromised cases.The estimated annual numbers meningitis cases industrialized countries about 4-6 per 100,000 people.Meningococcal disease caused by bacterium Neisseria meningitides, have A; C, Y, W-135 serogroups.Immunization helps to protect humans from...
Since the discovery of vitamin C many studies have illustrated its characteristic effect as a tumor prevention agent.Conversely: extracellular presence lactate dehydrogenase (LDH) is associated with cell necrosis and tissue breakdown therefore considered marker.In present study effects on levels oral LDH was estimated during development squamous carcinoma.Histological findings revealed changes in animals treated dimethyl benzanthracene (DMBA) alone or DMBA such moderate dysplasia basal...