A5074778052- melanin and skin pigmentation
- Biological and pharmacological studies of plants
- Bioactive natural compounds
- Diet, Metabolism, and Disease
- Alcohol Consumption and Health Effects
- Liver Disease Diagnosis and Treatment
Zhejiang University of Technology
2019
Objectives. Fatty liver disease (FLD) is a major cause of morbidity and mortality worldwide. Dietary cholesterol alcohol consumption are important risk factors for the progression FLD, but whether how induces more severe FLD with ingestion remain unclear. Herein, we mainly used Lieber-DeCarli diet to establish mouse model investigate synergistic effects metabolism on damage. The indices aspartate transaminase (AST), alanine (ALT), low-density lipoprotein (LDL-c), total (TC) levels,...
In order to establish the extraction technology of flavonoids from Dendrobium officinale leaves, a method combining Plackett–Burman design (PBD), steepest ascent design, and central composite was developed optimize flavonoids. addition, tyrosinase activity inhibition further tested in vitro. PBD results showed that ethanol concentration number extractions were key factors. Response surface methodology (RSM) indicated optimal conditions 78% concentration, six times, 2 h, 1:50 solid-liquid...