A5037065993- Peripheral Neuropathies and Disorders
- Multiple Sclerosis Research Studies
- Autoimmune Neurological Disorders and Treatments
- Parkinson's Disease and Spinal Disorders
- Spatial Neglect and Hemispheric Dysfunction
- Epilepsy research and treatment
- Myasthenia Gravis and Thymoma
- Polyomavirus and related diseases
- RNA regulation and disease
- Neurobiology of Language and Bilingualism
- Alzheimer's disease research and treatments
- Cerebral Venous Sinus Thrombosis
- Action Observation and Synchronization
- Mitochondrial Function and Pathology
- Neurogenetic and Muscular Disorders Research
- Cerebrospinal fluid and hydrocephalus
- Botulinum Toxin and Related Neurological Disorders
- Hereditary Neurological Disorders
- Genetic Neurodegenerative Diseases
- Ophthalmology and Eye Disorders
- Peripheral Nerve Disorders
- Amyotrophic Lateral Sclerosis Research
- Meningioma and schwannoma management
- Migraine and Headache Studies
- Neurofibromatosis and Schwannoma Cases
AHEPA University Hospital
2015-2025
Aristotle University of Thessaloniki
2014-2025
The use of immune checkpoint inhibitors (ICIs) for the treatment various advanced and aggressive types malignancy has significantly increased both survival long-term remission rates. ICIs block crucial inhibitory pathways system, in order to trigger an aggravated response against tumor. However, this enhanced activation leads development numerous immune-related adverse events (irAEs), which may affect any system. Although severe neurological irAEs are relatively rare, they carry a high...
(Headache 2011;51:1285-1288) Background.— The association of headache with transient neurological deficits and cerebrospinal fluid lymphocytosis (HaNDL) is recognized as a distinct benign, self-limited syndrome. Aphasic, sensory motor disturbances predominate the clinical picture to our knowledge, only 2 detailed cases confusion agitation have been previously described. Case.— We present recent experience HaNDL syndrome who, in addition focal deficits, developed confusional state variable...
Choroid plexus (CP) can be seen as a watchtower of the central nervous system (CNS) that actively regulates CNS homeostasis. A growing body literature suggests CP alterations are involved in pathogenesis multiple sclerosis (MS) but underlying mechanisms remain elusive. CPs enlarged and inflamed relapsing-remitting (RRMS) also clinically isolated syndrome (CIS) radiologically (RIS) stages, far beyond MS diagnosis. Increases choroid plexus/total intracranial volume (CP/TIV) ratio have been...
Background: Natalizumab (NTZ) and fingolimod (FTY) are second-line disease modifying treatments (DMTs) approved for Relapsing – Remitting Multiple Sclerosis (RRMS). Few studies available on a direct comparison between NTZ FTY, based post-marketing experience, with conflicting results reporting relatively short follow-up period. Aim: We hereby report real-world experience of MS Center respect to vs. FTY in terms efficacy safety, referencing long-term follow-up. Methods: used retrospective...
Background and Objectives: Despite the increasing use of biomarkers, differentiation between Alzheimer’s disease (AD), behavioral variant Frontotemporal Dementia (bvFTD), Primary Progressive Aphasia (PPA) remains a challenge. Apraxia is supportive feature for diagnosing AD but underrepresented in other dementia types. Herein, we investigated presence characteristic profiles limb, verbal, non-verbal apraxia three major Materials Methods: Test Upper Limb (TULIA) Battery Adults—2 (ABA-2) were...
Background and Objectives: Rare diseases (RDs) are life-threatening or chronically impairing conditions that affect about 6% of the world's population. RDs often called 'orphan' diseases, since people suffering from them attract little support national health systems. Aim: The aim this study is to describe clinical characteristics of, available laboratory examinations for, patients who were hospitalized in a tertiary referral center finally received diagnosis associated with Neurological...
Objectives: Natalizumab (NTZ), a treatment indicated for patients with highly active Relapsing – Remitting Multiple Sclerosis (RRMS), is known to induce increased relative frequency of lymphocytes. Progressive Multifocal Leukoencephalitis (PML) rare but serious adverse event related NTZ. Moreover, reduced L-selectin (CD62L) expression in T-cells cryopreserved samples RRMS under NTZ has been proposed as biomarker pre-PML state. We explore the association between and hematological parameters...
X-linked Charcot-Marie-Tooth disease (CMT 1X) is the second most common form of inherited demyelinating neuropathy. It established that patients suffering from CMT 1X can have episodes hemiparesis, paraparesis, quadriparesis, ataxia, aphasia, and dysarthria, which be fully reversible, 'trigger' factors for these are usually febrile illness, high altitudes, hyperventilation, physical activity. We describe a 22-year-old patient with history viral infection sleep deprivation who presented to...
The development and further optimization of the diagnostic criteria for multiple sclerosis (MS) emphasize establishment an early accurate diagnosis. So far, numerous studies have revealed significance treatment administration MS its association with slower disease progression better late outcomes regards to disability accumulation. However, according current research results, both neuroinflammatory neurodegenerative processes may exist prior symptom initiation. Despite fact that a...